What’s stopping you from trying a GLP / meds?

[Anonymous]

Anonymous wrote:

Anonymous wrote:I will say the majority of women I know using GLPs simply don't want to do the hard work of cleaning up their diets and exercising regularly. There are no particular obstacles there, they just don't want to. Some women were dealt a more challenging genetic hand, for sure, but I do believe prescription meds should always be the last resort. If you end up really needing them, fine, but why put any medication into your body unnecessarily? Especially when most will need to stay on it forever?

Cleaning up diet and exercising require a regimented life style, because you need sufficient sleep to recover from workouts. Which means workout can't be too early or too late. During the years where I was super lean, I made little progression in my career. During the years where I made moves good for my comp, I tend to gain a bit of weight. Not saying meds are the solution. But don't pretend we live in a upper middle class bubble where someone else took care of you.

Trading comp for feeling like dog shit is a bad exchange. The most effective people I know live regimented lifestyles and they don’t work all the time because high value thinking gets attenuated very quickly when you aren’t sleeping.

To each their own.

[Anonymous]

As someone who is taking a GLP-1 because I truly was obese (now I'm just overweight, woo), I take a lot of offense at some of what people are saying here. Most of us that are taking this medication for a real medical reason are doing it under medical supervision. I see a doctor or NP, as well as a dietician, monthly. I exercise and lift weights daily. I have completely overhauled my diet. This was a lifestyle change in addition to taking a MEDICATION. It is a MEDICINE. I'm so offended by you people who are out there saying I could have just eaten less, I'm just taking this for vanity, being skinny is so important to me. Nope, this is about my HEALTH. I am taking MEDICINE to IMPROVE MY HEALTH.

So many here think it's just about being thin. It's not, it's about being healthy.

Taking this MEDICINE is no different than you taking Synthroid for your thyroid issues or prozac for your depression or Lexapro for your high anxiety. Or your little boy taking Adderall for his ADHD. I'm not here telling your son to just calm down, he doesn't need ADHD medicine, am I?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:These posts are so dumb. So much hand wringing about how other women choose to lose weight. Why do you even care? It's like the same as those women who crow about how other women shouldn't have abortions. Like why do they even care? You're against abortion? Then don't have one. You're against GLP1s? Then don't take them. Who gives a flying F if someone else does? At least the abortion crazies have the whole "you're killing a baby" argument. What do the GLP1 crazies have?

You're calling the people who are recommending caution "the GLP crazies"? I think you have it backwards. There is constant proselytizing, really, like they are new converts to a religion.

DP but it seems to me more that people on GLP-1s are constantly having to defend their decisions. So what may seem like proselytizing to you is actually just defending themselves. Either way, people need to stop talking about this - it's a personal decision and it should stay personal. I'm not talking to people every day about any medication that I'm on!

Look at the first two pages on this diet forum. It’s overwhelmingly about GLP1. I think you underestimate how some folks really try and make this the baseline way to lose weight.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

[Anonymous]

Anonymous wrote:

Anonymous wrote:What’s stopping me is having success through diet and exercise. I’m mid-40s and have lost 20 pounds in the last year through a modest deficit (1850 calories a day), walking and strength training. I started this journey with the goal of longevity though. That really motivated me to show up and stay consistent. Losing weight was a great side effect.

I have been on 1200, strength train for over a decade and can't lose weight. I think the prime muscle development years was 14-24 and that boat sailed decades ago. Heavy weights can help you keep whatever you had but no woman is going to be the Rock in this life time.

1200 is terrible for weight loss. Also your window for muscle development is too narrow. Again some of you are really uneducated, geeze.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

Nonetheless, many people here are on GLPs and are perfectly happy with no mood issues whatsoever. Meanwhile, on this thread, the suggestion was given to regiment one's life much more, add 1+ hours of exercise per day and cut calories even more for a person who was already exercising plenty and eating only 1400 calories. Maybe you should be more worried about mental wellbeing of those who need to go to extreme lengths just to reach a healthy weight.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

Nonetheless, many people here are on GLPs and are perfectly happy with no mood issues whatsoever. Meanwhile, on this thread, the suggestion was given to regiment one's life much more, add 1+ hours of exercise per day and cut calories even more for a person who was already exercising plenty and eating only 1400 calories. Maybe you should be more worried about mental wellbeing of those who need to go to extreme lengths just to reach a healthy weight.

and taking glps isn't extreme?!

[Anonymous]

Especially in older adults, there are some concerns regarding sarcopenia, and even dementia:

Are we trading an obesity epidemic for a frailty epidemic?
Dr. Rostova: “We are certainly walking a tightrope. The cardiometabolic benefits of losing visceral fat are undeniable—we are reducing heart failure, liver disease, and systemic inflammation. However, the medical community initially viewed GLP-1s as a standalone cure. We now know they are merely a metabolic catalyst. If you prescribe these drugs without simultaneously prescribing physical movement, you are absolutely accelerating physical frailty, particularly in patients over 60.”
https://harvardsciencereview.org/2026/02/23/the-glp-1-aftermath-what-the-science-says-about-muscle-loss-and-cellular-aging/

Long-Term Risk of Cognitive Impairment with GLP-1 Analogues in Older Adults with Type 2 Diabetes Mellitus
Among older adults with type 2 diabetes, GLP-1 analogues were associated with an increased risk of cognitive impairment secondary to a larger, decreased risk of mortality. However, caution may be warranted in prescribing GLP-1 analogues to the oldest patients.
https://www.aan.com/msa/Public/Events/AbstractDetails/65026

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

Nonetheless, many people here are on GLPs and are perfectly happy with no mood issues whatsoever. Meanwhile, on this thread, the suggestion was given to regiment one's life much more, add 1+ hours of exercise per day and cut calories even more for a person who was already exercising plenty and eating only 1400 calories. Maybe you should be more worried about mental wellbeing of those who need to go to extreme lengths just to reach a healthy weight.

and taking glps isn't extreme?!

NP-It's one shot a week, tapering down over time to a very low dose. That's a lot less extreme than 3 hours of exercise a day (yes, someone recommended that) and massive calorie restriction. It's also a lot less extreme than all the meds one inevitably ends up having to take if staying obese for decades.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

Nonetheless, many people here are on GLPs and are perfectly happy with no mood issues whatsoever. Meanwhile, on this thread, the suggestion was given to regiment one's life much more, add 1+ hours of exercise per day and cut calories even more for a person who was already exercising plenty and eating only 1400 calories. Maybe you should be more worried about mental wellbeing of those who need to go to extreme lengths just to reach a healthy weight.

and taking glps isn't extreme?!

NP-It's one shot a week, tapering down over time to a very low dose. That's a lot less extreme than 3 hours of exercise a day (yes, someone recommended that) and massive calorie restriction. It's also a lot less extreme than all the meds one inevitably ends up having to take if staying obese for decades.

Every discussion I've read on here about it revolves around *increasing the amount. Any talk of tapering is from the vanity microdosers. Most discuss it being a lifelong drug like insulin or high blood pressure medicine. None of ya'll wants to find out what happens when you stop. And no one wants to discuss the, as yet unidentified, long term impacts or the weird short term impacts such as side effects and improper emptying of the stomach and bowels. How are you going to fast/clear out for surgery or colonoscopy?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

Nonetheless, many people here are on GLPs and are perfectly happy with no mood issues whatsoever. Meanwhile, on this thread, the suggestion was given to regiment one's life much more, add 1+ hours of exercise per day and cut calories even more for a person who was already exercising plenty and eating only 1400 calories. Maybe you should be more worried about mental wellbeing of those who need to go to extreme lengths just to reach a healthy weight.

and taking glps isn't extreme?!

NP-It's one shot a week, tapering down over time to a very low dose. That's a lot less extreme than 3 hours of exercise a day (yes, someone recommended that) and massive calorie restriction. It's also a lot less extreme than all the meds one inevitably ends up having to take if staying obese for decades.

Every discussion I've read on here about it revolves around *increasing the amount. Any talk of tapering is from the vanity microdosers. Most discuss it being a lifelong drug like insulin or high blood pressure medicine. None of ya'll wants to find out what happens when you stop. And no one wants to discuss the, as yet unidentified, long term impacts or the weird short term impacts such as side effects and improper emptying of the stomach and bowels. How are you going to fast/clear out for surgery or colonoscopy?

This forum is a pretty poor source for information. Increasing the amount is called for when the weight loss halts or the hunger isn't well managed. If you're losing at an acceptable rate, you don't increase. After you reach your goal weight and are in maintenance, you should decrease by quite a bit. Also, the doctors know how to handle dealing with emptying the bowels before surgery or colonoscopy. That's really not a concern.

FWIW, I tried calorie restriction and exercise for the last 3 or so years, but the weight kept creeping up. I tried IF. Still gained weight. I completely gave up alcohol (down from maybe 7 drinks per week). Still gained. 2 months into a GLP, and still on a "ramp up" dose, and I've already lost 10 lbs. I feel great, and my doctor is keeping me on the 0.5 mg dose since it's working. Maybe there are long term impacts that should concern me, but there are also pretty alarming long term impacts to being obese and prediabetic.

[Anonymous]

Anonymous wrote:I will say the majority of women I know using GLPs simply don't want to do the hard work of cleaning up their diets and exercising regularly. There are no particular obstacles there, they just don't want to. Some women were dealt a more challenging genetic hand, for sure, but I do believe prescription meds should always be the last resort. If you end up really needing them, fine, but why put any medication into your body unnecessarily? Especially when most will need to stay on it forever?

Three people in my life know both that I'm on this and how many hours I work, and I'm married to one of them. You don't know who is on it and you don't know what obstacles anyone is dealing with.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I think the talk of less enjoyment misses the fact that when you are overweight and feel like crap about yourself, you're not enjoying life either. "Ozempic personality"seems like a gross clickbait term to yet again stigmatize people around weight, as if now congrats, society won't judge you for being fat anymore, but your personality sure does suck!

One reason why glps work to stop overeating is because it diminishes the so called "food noise." This noise is also at work when you want to drink alcohol, have sex, basically the noise is a motivator of desire and enjoyment. Glps quiet the noise, resulting in anhedonia in many people. Anhedonia can lead to depression. At least you're thin.

Oh good grief! None of this is true whatsoever. Food noise has nothing to do with libido or ability to enjoy things in life, and you're obviously just trolling.

Many obese people are constantly hungry, are constantly depriving themselves and on diets, are working out a lot, and then have to deal with feeling like failures when the scale doesn't budge. We have to feel like pathetic slobs all of the time, even though we're often working twice as hard as the rest of you. Then, if we push ourselves much at the gym or hiking or whatever, we get sore knees or have other significant pain. If we try to do something fun, we have to worry about the knees crapping out mid hike or whatever. Many hobbies are less fun due to the extra weight. Being obese really sucks. Going from being obese to being a normal weight improves one's quality of life tremendously. Reducing food noise is just that and nothing more. Slowing the emptying of the stomach makes you feel more sated and less hungry. It is not mood altering.

Sheesh.

Some of you show your ignorance. It would be good for you to learn more about receptor activity.

Nonetheless, many people here are on GLPs and are perfectly happy with no mood issues whatsoever. Meanwhile, on this thread, the suggestion was given to regiment one's life much more, add 1+ hours of exercise per day and cut calories even more for a person who was already exercising plenty and eating only 1400 calories. Maybe you should be more worried about mental wellbeing of those who need to go to extreme lengths just to reach a healthy weight.

and taking glps isn't extreme?!

NP-It's one shot a week, tapering down over time to a very low dose. That's a lot less extreme than 3 hours of exercise a day (yes, someone recommended that) and massive calorie restriction. It's also a lot less extreme than all the meds one inevitably ends up having to take if staying obese for decades.

Every discussion I've read on here about it revolves around *increasing the amount. Any talk of tapering is from the vanity microdosers. Most discuss it being a lifelong drug like insulin or high blood pressure medicine. None of ya'll wants to find out what happens when you stop. And no one wants to discuss the, as yet unidentified, long term impacts or the weird short term impacts such as side effects and improper emptying of the stomach and bowels. How are you going to fast/clear out for surgery or colonoscopy?

You only increase dose as you are starting and then continuing to lose weight. Once you are losing weight steadily, you do not keep going up in dose. You remain at that dose unti the goal is achieved, and then you lower the dose for maintenance. That is how it is typically done. Personally I have completely normal bowel movements every day as I did before. But plenty of people taking GLP1s are having surgery and colonoscopies every day and discuss these concerns with their doctors.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I’m in healthcare and I keep up with the latest research on this. The fact is, we don’t know what all the long term impacts are at this point. Newer studies are now showing that there are potential serious adverse effects on the kidneys and pancreas- you don’t want to mess with that. There’s a reason that doctors don’t want people going on this to lose vanity weight.

"in healthcare" - are you a doctor?

Can you cite the studies?

I assume a lot of people here are very smart - do you really believe all of this stuff that "people say" about the drugs or are you all getting this information from doctors and peer reviewed studies? Just stop stop stop with the misinformation. People want so badly for the negative stuff to be true.

Anyone can say they're in healthcare. That person could work data processing for a payment system and work in healthcare.

Definitely not in data processing, lol. I have to stay on top of all the research because I work directly with patients. No one is spreading any misinformation, everyone has access to google and medical journals (I just subscribe to a lot and get them directly to my email). I can copy and paste articles, which is a waste of my time to gather all this information for internet strangers when you can easily find it for yourself.

Of course there are adverse reactions and side effects… that is pretty much any medication. Here’s what’s being discussed right now for GLP’s:

Risk for thyroid C cell tumors
Gastroparesis (which can be irreversible and trust me, you don’t want this).
Gallbladder issues.

And by the way, I never told anyone not to take them. You people get so oddly defensive about your life choices. I said doctors are not keen to prescribe these for vanity reasons and there is a good reason for that.

Here’s another Medscape article written by a (gasp) doctor and not someone working at a data center:
https://www.medscape.com/viewarticle/1003255

You’re oddly cagey about the area of healthcare you work in. Do you work for or with the insurance industry?

No response from the PP. Draw your own conclusions about why they’re trying to scare us away from GLP1s.

[Anonymous]

i started medicare this year. Have sleep apnea but HATE the cpap.

for next annual will talk to doctor about zepbound. Seems it is covered by medicare for sleep apnea if BMI is over 30. I go between 29 and 31 so easy to make BMI just to be covered.

curious of others on medicare have any experience with zepbound.