Mayim Bialik's horrific experience on GLP-1's

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

What is the link between GLP1 usage and increased cardiac risk, or increased gastric cancer risk?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

Not only the drugs but the gastric bypass and bands didn't work either. Bodies adapt and we'll likely see this with the drugs over time. Then we'll be on to the next craze.

My friend got a gastric sleeve in Tijuana. She lost 20 pounds in the first 3 months. She began consuming milk shakes, ice cream and other calorie laden foods which overrode her surgery. Within a year of her surgery, she basically stretched her stomach back out (or something), resumed her previous overeating habits, regained the weight lost and added 20 pounds more. Moral: people will do anything, other than address the core reasons for their overeating (which is evidenced by their relentless "food noise") to lose weight. Sadly, without significant habit changes, lifestyle changes and psychological growth, the WEIGHT ALWAYS COMES BACK.

Weight virtually always comes back regardless of lifestyle changes. 90-95% who have lost significant weight gain all or more than all of it back within 5 years.

Which is why this medication is so life changing for a subset of that chronically overweight/obese population- it keeps their weight down into a healthy range. Yes there are side effects and for some people, those are bothersome enough to not want the medication, even if it means they remain obese and have a shorter life expectancy. For many, the side effects are mild and they are finally able to keep their bodies at a healthy weight which lowers their risk of myriad diseases. It's an amazing medication, when used as intended in a population that would see medical benefits from it. I am not interested in stories of celebrities with BMIs of 23 who are taking it to bring their BMIs down to 19. Or stories of people using it because of body dysmorphia, or to augment their eating disorder. That's not a reason to pull it from the market or claim it's dangerous. It's literally out there saving millions of lives.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I find it fascinating how over the top the reactions are to this. Like OP has insulted your mother and you must come to her defense. So much anger and disdain. It's weird.

Oh hey OP. Glad to see you're back.

I consider it infinitely weirder to post for the 247th time about something that doesn't concern you at all. Thanks!

How does this concern you?

That's fire but I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE nor the NHS in UK. R

I have been taking Ozempic for five years now. Very few side effects, monitored by my doctor, brought my cholesterol, triglycerides, A1C and BP back down to normal. Any other questions I can answer for you?

How nice. But you're not the only one allowed to comment or discuss.

Did I preclude anyone from commenting? Comment away and I'll say what I want to say in response.

How does someone talking about Mayim's experience concern you? It doesn't. So get used to seeing posts like this.

No, I don't think I will. I will point out how dumb and idiotic it is each and every time I see posts like this. Get used to it.

Oh, I will. I enjoy these threads and how worked up you get.

I defend drugs with pesky facts. It doesn't matter if I've used them or not. Drugs are great. This one has extended and improved millions of lives world wide over two decades. #winning

I will still read about the negative experiences the way I read bad hotel or restaurant reviews. I take all the rave review with a grain of salt.

That's fine. I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE or the NHS in UK. Really whatever they think is a good source of info on meds.

I'm not looking at random posters to "defend drugs" I can do that on my own time what I am interested is other's experiences. It's a conversation and people can take it or leave it. But trying to halt the discussion and shut it down is weird. What are people so afraid of?

If you are not trolling I am happy to share my actual experience! I'm 5'5. My BMI was always around 22-23, until I hit 35 and had 3 kids in 5 years. Now, at 45, my BMI had hovered around 28-29 since that first pregnancy. I would diet, and lose 10 pounds here and there, but of course it always came back. Exercise didn't help with weight loss, which most of us know, but I did exercise religiously as well. I could bring my weight down to about 160 (only 10lb "overweight" per BMI calculator) with extreme effort but it always popped back up to 17-175. I thought about GLP1 for over a year, asked my doctor, my doctor said she doesnt like to prescribe it until BMI hits 30 PLUS either bad bloodwork or high blood pressure. Finally, about one year ago, I just went online and got it. The online company (Ro, if anyone is interested) was able to get my insurance to cover it because my bloodwork showed high cholesterol and my BP has always been borderline around 130/80 since having kids, so I did meet prescribing criteria even if my own personal physician didn't think things were bad enough to want to prescribe it to me.

I've been on it for a year at the lowest starting dose, never increased the dose never needed to (the 2.5 of zepbound). I've stretched it out to once every 2 weeks. I went from 175 to 135 in about 6 months and I did think my face looked a little sunken at first, but thankfully since i'm premenopausal and maybe because I hadn't been fat for super long, just 10 years, my face looks normal again now and I dont have any loose skin problems. I had nausea and low energy for the first 2 weeks on it, I got dizzy a few times which prompted me to check my blood sugar at home (and it was normal), and I remember thinking it was worth it because of the weight loss but that I didn't love how it made me feel, I was having to count calories and make sure I was hitting at least a thousand a day so that i wouldn't feel weak, but it was hard to get to a thousand. After a few weeks those problems went away (i never had GI problems or anything). Now on the days I do count calories, i'm getting between 1300-1700 most days, and my weight has been stable at 135 for about 6 months. I enjoy food, i just stop when Im full which is much sooner than it used to be. i have zero side effects. My BP is now 110s/70s and my cholesterol is normal. My PCP is aware i'm taking it and she says it seems like it's working well for me and has no problem with my being on it and has said she's started to loosen her own personal restrictions on prescribing it to people since seeing so many patients go on it and do well, and she's taken over prescribing for me so I dont have to pay Ro every month anymore.

Anyways that's my honest story.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

Of course not, I'm responding to your statement about not wanting to take the medication until it's been used safely on non diabetics for more years. You said, "Same. I'm not overweight nor diabetic and have no need to be a guinea pig." This was in response to someone saying, I quote, "I, who does not have diabetes, would rather wait until it's been used safely on people like me". You're basically discussing at what point you'd feel comfortable using the drug. And i'm saying, why on earth would you ever want to use a drug for weight loss if you're not overweight? Count your blessings and continue your non overweight life! I don't sit around wondering when I'd feel comfortable starting to take migraine medications when I don't suffer from migraines.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

Of course not, I'm responding to your statement about not wanting to take the medication until it's been used safely on non diabetics for more years. You said, "Same. I'm not overweight nor diabetic and have no need to be a guinea pig." This was in response to someone saying, I quote, "I, who does not have diabetes, would rather wait until it's been used safely on people like me". You're basically discussing at what point you'd feel comfortable using the drug. And i'm saying, why on earth would you ever want to use a drug for weight loss if you're not overweight? Count your blessings and continue your non overweight life! I don't sit around wondering when I'd feel comfortable starting to take migraine medications when I don't suffer from migraines.

Why would you think I care about what you do in your spare time? Run along now.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

Of course not, I'm responding to your statement about not wanting to take the medication until it's been used safely on non diabetics for more years. You said, "Same. I'm not overweight nor diabetic and have no need to be a guinea pig." This was in response to someone saying, I quote, "I, who does not have diabetes, would rather wait until it's been used safely on people like me". You're basically discussing at what point you'd feel comfortable using the drug. And i'm saying, why on earth would you ever want to use a drug for weight loss if you're not overweight? Count your blessings and continue your non overweight life! I don't sit around wondering when I'd feel comfortable starting to take migraine medications when I don't suffer from migraines.

Why would you think I care about what you do in your spare time? Run along now.

What are you even responding to? I swear, the number of trolls on this site has gotten exponentially worse

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

Of course not, I'm responding to your statement about not wanting to take the medication until it's been used safely on non diabetics for more years. You said, "Same. I'm not overweight nor diabetic and have no need to be a guinea pig." This was in response to someone saying, I quote, "I, who does not have diabetes, would rather wait until it's been used safely on people like me". You're basically discussing at what point you'd feel comfortable using the drug. And i'm saying, why on earth would you ever want to use a drug for weight loss if you're not overweight? Count your blessings and continue your non overweight life! I don't sit around wondering when I'd feel comfortable starting to take migraine medications when I don't suffer from migraines.

Why would you think I care about what you do in your spare time? Run along now.

What are you even responding to? I swear, the number of trolls on this site has gotten exponentially worse

The topic of this thread is Mayim Bialik. Everyone else's personal sob story and vendetta is just off topic.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

Of course not, I'm responding to your statement about not wanting to take the medication until it's been used safely on non diabetics for more years. You said, "Same. I'm not overweight nor diabetic and have no need to be a guinea pig." This was in response to someone saying, I quote, "I, who does not have diabetes, would rather wait until it's been used safely on people like me". You're basically discussing at what point you'd feel comfortable using the drug. And i'm saying, why on earth would you ever want to use a drug for weight loss if you're not overweight? Count your blessings and continue your non overweight life! I don't sit around wondering when I'd feel comfortable starting to take migraine medications when I don't suffer from migraines.

Why would you think I care about what you do in your spare time? Run along now.

What are you even responding to? I swear, the number of trolls on this site has gotten exponentially worse

The topic of this thread is Mayim Bialik. Everyone else's personal sob story and vendetta is just off topic.

Well, to be fair, the OP opened her post with the article and then immediately started talking about, in the very first post, how she didn't like how people were just getting prescribed this medication right and left these days and no one was educating them about the potential side effects like the ones Mayim had. Which is patently untrue, the side effects are well publicized, and horrific ones like the ones Mayim described are exceedingly rare. And people are sharing their own stories and opinions about the prescribing of the meds, and the side effects. So pretty much everything is on topic, except for people saying "I'm not overweight and I don't think I'd be interested in taking these drugs without more long term studies!" which sounds very stupid considering not being overweight would, theoretically, make you not interested in taking them even if there were 2435245 year longitudinal studies showing zero side effects and zero bad outcomes, because, you don't need to lose weight. It makes one wonder why you care to discuss these meds that have no bearing on your life. I don't go onto diabetes discussions and talk about how i don't like the fact that insulin drops your blood sugar so fast and I'd not personally be comfortable taking high doses of insulin, but you know, to each her own i guess, good luck with those fluctuating blood sugars, don't say I didn't warn you!!!!! And totally ignoring the fact that I don't have diabetes so, like, no sh** I wouldn't take insulin.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I find it fascinating how over the top the reactions are to this. Like OP has insulted your mother and you must come to her defense. So much anger and disdain. It's weird.

Oh hey OP. Glad to see you're back.

I consider it infinitely weirder to post for the 247th time about something that doesn't concern you at all. Thanks!

How does this concern you?

That's fire but I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE nor the NHS in UK. R

I have been taking Ozempic for five years now. Very few side effects, monitored by my doctor, brought my cholesterol, triglycerides, A1C and BP back down to normal. Any other questions I can answer for you?

How nice. But you're not the only one allowed to comment or discuss.

Did I preclude anyone from commenting? Comment away and I'll say what I want to say in response.

How does someone talking about Mayim's experience concern you? It doesn't. So get used to seeing posts like this.

No, I don't think I will. I will point out how dumb and idiotic it is each and every time I see posts like this. Get used to it.

Oh, I will. I enjoy these threads and how worked up you get.

I defend drugs with pesky facts. It doesn't matter if I've used them or not. Drugs are great. This one has extended and improved millions of lives world wide over two decades. #winning

I will still read about the negative experiences the way I read bad hotel or restaurant reviews. I take all the rave review with a grain of salt.

That's fine. I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE or the NHS in UK. Really whatever they think is a good source of info on meds.

I'm not looking at random posters to "defend drugs" I can do that on my own time what I am interested is other's experiences. It's a conversation and people can take it or leave it. But trying to halt the discussion and shut it down is weird. What are people so afraid of?

If you are not trolling I am happy to share my actual experience! I'm 5'5. My BMI was always around 22-23, until I hit 35 and had 3 kids in 5 years. Now, at 45, my BMI had hovered around 28-29 since that first pregnancy. I would diet, and lose 10 pounds here and there, but of course it always came back. Exercise didn't help with weight loss, which most of us know, but I did exercise religiously as well. I could bring my weight down to about 160 (only 10lb "overweight" per BMI calculator) with extreme effort but it always popped back up to 17-175. I thought about GLP1 for over a year, asked my doctor, my doctor said she doesnt like to prescribe it until BMI hits 30 PLUS either bad bloodwork or high blood pressure. Finally, about one year ago, I just went online and got it. The online company (Ro, if anyone is interested) was able to get my insurance to cover it because my bloodwork showed high cholesterol and my BP has always been borderline around 130/80 since having kids, so I did meet prescribing criteria even if my own personal physician didn't think things were bad enough to want to prescribe it to me.

I've been on it for a year at the lowest starting dose, never increased the dose never needed to (the 2.5 of zepbound). I've stretched it out to once every 2 weeks. I went from 175 to 135 in about 6 months and I did think my face looked a little sunken at first, but thankfully since i'm premenopausal and maybe because I hadn't been fat for super long, just 10 years, my face looks normal again now and I dont have any loose skin problems. I had nausea and low energy for the first 2 weeks on it, I got dizzy a few times which prompted me to check my blood sugar at home (and it was normal), and I remember thinking it was worth it because of the weight loss but that I didn't love how it made me feel, I was having to count calories and make sure I was hitting at least a thousand a day so that i wouldn't feel weak, but it was hard to get to a thousand. After a few weeks those problems went away (i never had GI problems or anything). Now on the days I do count calories, i'm getting between 1300-1700 most days, and my weight has been stable at 135 for about 6 months. I enjoy food, i just stop when Im full which is much sooner than it used to be. i have zero side effects. My BP is now 110s/70s and my cholesterol is normal. My PCP is aware i'm taking it and she says it seems like it's working well for me and has no problem with my being on it and has said she's started to loosen her own personal restrictions on prescribing it to people since seeing so many patients go on it and do well, and she's taken over prescribing for me so I dont have to pay Ro every month anymore.

Anyways that's my honest story.

Thank you. Can I ask how high your cholesterol was? Mine is highisr but not in the “very high” category. I’m very similar although gained the weight in my late 40s, not after pregnancy. It’s like my whole body reset at age 47.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I find it fascinating how over the top the reactions are to this. Like OP has insulted your mother and you must come to her defense. So much anger and disdain. It's weird.

Oh hey OP. Glad to see you're back.

I consider it infinitely weirder to post for the 247th time about something that doesn't concern you at all. Thanks!

How does this concern you?

That's fire but I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE nor the NHS in UK. R

I have been taking Ozempic for five years now. Very few side effects, monitored by my doctor, brought my cholesterol, triglycerides, A1C and BP back down to normal. Any other questions I can answer for you?

How nice. But you're not the only one allowed to comment or discuss.

Did I preclude anyone from commenting? Comment away and I'll say what I want to say in response.

How does someone talking about Mayim's experience concern you? It doesn't. So get used to seeing posts like this.

No, I don't think I will. I will point out how dumb and idiotic it is each and every time I see posts like this. Get used to it.

Oh, I will. I enjoy these threads and how worked up you get.

I defend drugs with pesky facts. It doesn't matter if I've used them or not. Drugs are great. This one has extended and improved millions of lives world wide over two decades. #winning

I will still read about the negative experiences the way I read bad hotel or restaurant reviews. I take all the rave review with a grain of salt.

That's fine. I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE or the NHS in UK. Really whatever they think is a good source of info on meds.

I'm not looking at random posters to "defend drugs" I can do that on my own time what I am interested is other's experiences. It's a conversation and people can take it or leave it. But trying to halt the discussion and shut it down is weird. What are people so afraid of?

If you are not trolling I am happy to share my actual experience! I'm 5'5. My BMI was always around 22-23, until I hit 35 and had 3 kids in 5 years. Now, at 45, my BMI had hovered around 28-29 since that first pregnancy. I would diet, and lose 10 pounds here and there, but of course it always came back. Exercise didn't help with weight loss, which most of us know, but I did exercise religiously as well. I could bring my weight down to about 160 (only 10lb "overweight" per BMI calculator) with extreme effort but it always popped back up to 17-175. I thought about GLP1 for over a year, asked my doctor, my doctor said she doesnt like to prescribe it until BMI hits 30 PLUS either bad bloodwork or high blood pressure. Finally, about one year ago, I just went online and got it. The online company (Ro, if anyone is interested) was able to get my insurance to cover it because my bloodwork showed high cholesterol and my BP has always been borderline around 130/80 since having kids, so I did meet prescribing criteria even if my own personal physician didn't think things were bad enough to want to prescribe it to me.

I've been on it for a year at the lowest starting dose, never increased the dose never needed to (the 2.5 of zepbound). I've stretched it out to once every 2 weeks. I went from 175 to 135 in about 6 months and I did think my face looked a little sunken at first, but thankfully since i'm premenopausal and maybe because I hadn't been fat for super long, just 10 years, my face looks normal again now and I dont have any loose skin problems. I had nausea and low energy for the first 2 weeks on it, I got dizzy a few times which prompted me to check my blood sugar at home (and it was normal), and I remember thinking it was worth it because of the weight loss but that I didn't love how it made me feel, I was having to count calories and make sure I was hitting at least a thousand a day so that i wouldn't feel weak, but it was hard to get to a thousand. After a few weeks those problems went away (i never had GI problems or anything). Now on the days I do count calories, i'm getting between 1300-1700 most days, and my weight has been stable at 135 for about 6 months. I enjoy food, i just stop when Im full which is much sooner than it used to be. i have zero side effects. My BP is now 110s/70s and my cholesterol is normal. My PCP is aware i'm taking it and she says it seems like it's working well for me and has no problem with my being on it and has said she's started to loosen her own personal restrictions on prescribing it to people since seeing so many patients go on it and do well, and she's taken over prescribing for me so I dont have to pay Ro every month anymore.

Anyways that's my honest story.

Thank you. Can I ask how high your cholesterol was? Mine is highisr but not in the “very high” category. I’m very similar although gained the weight in my late 40s, not after pregnancy. It’s like my whole body reset at age 47.

Sure, it was exactly 200 on my last bloodwork that I did before getting prescribed (and I think 200 was the magic number to qualify as too high). It was always super low like 150 before I had kids and now it's back to that range. Same with the BP (always was 110s/70s and only went up to 130/80 after gaining weight after kids, now is back to what it used to be). So for me, those changes/ mild elevations seemed clearly weight related.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

What is the link between GLP1 usage and increased cardiac risk, or increased gastric cancer risk?

There isn't one. Did you mean to insinuate otherwise?

[Anonymous]

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Anonymous wrote:Did any of you read "Mayim Bialik: My GLP-1 Nightmare" article? It's amazing and eye opening for those of us who have not jumped on this bandwagon of GLP-1's. I really think they're not preparing those for the possible massive side effects and of course no one really knows the long term side effects for those who abused the medication to lose those last 20 pesky pounds. So few doctors are speaking up but when I've questioned a new of mine they mostly all say the same those meds should be used when it's a life or death situation like severe obesity is going to end someone's life. Whatever your personal thoughts are I'm glad she put her voice out there.

Free article: https://www.thefp.com/p/mayim-bialik-glp1-side-effects

NP. I am supposed to take seriously a rabid anti-vaxxer published by Bari Weiss?

I don't care what you do but you seem to think if you just use the right insult you will shut the conversation down. There are loads of active threads on this so that doesn't seem to be going too well for you.

Uh, are you crazy or something? I haven’t posted in this thread at all, and questioning the source is something smart people should always do, not that you’d understand that.

What is your issue? I don’t care what people discuss but I’m not going to read some hot nonsense from someone who has no credibility as a writer and take it seriously. Come back when you have an article from an actual legitimate source and stop trying to pretend your slop article is science.

Are you crazy? I'm not the OP. we are all allowed to discuss any aspect of this without hall monitors trying to shut it down. I don't need to come back with anything to placate you, nutter.

Please quote exactly, word for word, where I tried to shut down the conversation in my post. I want a specific quote. Tell me exactly what words I used that — and I am quoting you directly here — “shut the conversation down.” Give me my exact words where I said that, you crazy loon. Because I know you can’t. You made that up in your fevered and clearly insane mind.

Hint: not fawning over someone with a known history of RFK-level false statements about science and health does not equate to “shutting down a conversation.” It is doing what anyone smart should do: evaluating the source.

I want, tell me, give me. Who do you think you are? Buffoon.

So you can’t answer because you have no evidence. Typical ignorant MAGA wellness grifter who is upset her fake supplement business is getting deservedly trashed by GLP-1s.

[Anonymous]

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Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

If you're not overweight or diabetic why do you want to take a GLP1??

I don't and I won't but I'm interested I the discussion about this new drug that is suddenly so popular. Is that a crime?

Of course not, I'm responding to your statement about not wanting to take the medication until it's been used safely on non diabetics for more years. You said, "Same. I'm not overweight nor diabetic and have no need to be a guinea pig." This was in response to someone saying, I quote, "I, who does not have diabetes, would rather wait until it's been used safely on people like me". You're basically discussing at what point you'd feel comfortable using the drug. And i'm saying, why on earth would you ever want to use a drug for weight loss if you're not overweight? Count your blessings and continue your non overweight life! I don't sit around wondering when I'd feel comfortable starting to take migraine medications when I don't suffer from migraines.

Why would you think I care about what you do in your spare time? Run along now.

What are you even responding to? I swear, the number of trolls on this site has gotten exponentially worse

The topic of this thread is Mayim Bialik. Everyone else's personal sob story and vendetta is just off topic.

Well, to be fair, the OP opened her post with the article and then immediately started talking about, in the very first post, how she didn't like how people were just getting prescribed this medication right and left these days and no one was educating them about the potential side effects like the ones Mayim had. Which is patently untrue, the side effects are well publicized, and horrific ones like the ones Mayim described are exceedingly rare. And people are sharing their own stories and opinions about the prescribing of the meds, and the side effects. So pretty much everything is on topic, except for people saying "I'm not overweight and I don't think I'd be interested in taking these drugs without more long term studies!" which sounds very stupid considering not being overweight would, theoretically, make you not interested in taking them even if there were 2435245 year longitudinal studies showing zero side effects and zero bad outcomes, because, you don't need to lose weight. It makes one wonder why you care to discuss these meds that have no bearing on your life. I don't go onto diabetes discussions and talk about how i don't like the fact that insulin drops your blood sugar so fast and I'd not personally be comfortable taking high doses of insulin, but you know, to each her own i guess, good luck with those fluctuating blood sugars, don't say I didn't warn you!!!!! And totally ignoring the fact that I don't have diabetes so, like, no sh** I wouldn't take insulin.

Valiant effort, but it won’t matter. OP is one of the fake health influencers big mad that her fake business has been severely undercut by the widespread use of GLP-1s. She posts here all the time, desperate to discredit the twenty-plus years of research and data on these drugs to try to revive her business, but isn’t scientifically literate to understand what she is posting. So, she just lashes out indiscriminately.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

What is the link between GLP1 usage and increased cardiac risk, or increased gastric cancer risk?

There isn't one. Did you mean to insinuate otherwise?

No, I'm literally asking the poster above me who says "The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. "