10 units, or .5 mg, sg through Willow. It affected me a lot so I lost weight quickly and to be honest too fast so I never made it anywhere near their suggested full dose. 10 seems to be enough and may reduce further. |
Pp is right, Captain Obvious. |
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I'm about to start compounded semaglutide, and will be interested to see what it does. Over a 10-year period I lost 80 lbs, getting to my lowest just when COVID started (dammit!). I've gained 15 lbs back slowly, to where I am near the top of the overweight category in my late 50s. I've used low carb, low fat, low eating and they've all worked, and really quieted the food noise for a long time. (also helps to be living solo) I don't ever really dream of being THIN, but even just getting back to where I was pre-COVID (which was only about 5 lbs above what I weighed in high school and the highest end of the "normal" category) would be amazing.
I am hoping that perhaps I can be one who can get by on a low dose. I'm not diabetic, cholesterol actually dropped this past year (though is still above normal), and my blood pressure is well controlled with just a diuretic. But it's easy for me to get lazy both in terms of eating and in terms of exercise, and then it's harder to just clean up my act for a bit and see a drop in weight enough to motivate me to keep pushing. I guess I shall see. |
| 144 is slightly overweight, how do you qualify for the prescription? |
You can always have a doctor prescribe it off-label and pay out of pocket (rather than using insurance). Cash prices are a lot better than they used to be. Starter doses of Zepbound are only $300. |
Not being fat is not an advantage anymore. You do sound rather jealous/ annoyed. |
This. All of it. +1 |
Thanks for the PSA |
30 pounds of fat that you keep on after perimenopause is 30 pounds of estrogen production, which can raise your risk of breast and other cancers that feed on estrogen (which is a lot). In women, fat tissue produces estrogen, and this estrogen production continues through perimenopause and menopause. It will be interesting to see if GLPs cause a decrease in hormone positive cancer over the longer term. There is evidence on this for some cancers -- https://pubmed.ncbi.nlm.nih.gov/40839273/ |
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I did not read through this thread so forgive me if this has already been posted, but has anyone been on semaglutide for over a year without having their hunger/cravings return?
I was on semaglutide for a few months and it worked great and then my cravings came back. I was on various semaglutide groups and this seems like the standard outcome. I hear so many people say when first starting that they plan on doing this long term, but from what I can tell that's impossible. It seems like it losses effectiveness after 1-2 years at best. |
| So I’ve been on compounded ozempic for 4 months and have lost 15 pounds. I spent a month at .25 mg, a month at .5 mg and have been on 1 mg since. I’ve steadily lost about a pound a week. The most interesting thing to me is that we were on vacation for the past two weeks and I ate pretty much what I wanted, though didn’t overeat because I do get full, and lost a pound on vacation. |
I'm almost at the 2 years mark. Occasionally I have "breakthrough" hunger - but it's short and rare. I cannot believe the difference it's made in my everyday life. |
I love this too! |
| Seriously, it's a miracle and my only regret is not starting compounded sooner. IMO, all insurance companies should be covering these drugs if they want to cut long-term health costs. I feel and look better than I have in years. |
| I did mounjaro for 9 months and lost 50 lbs. it was great, but 10mg stopped working. I gained it all back over 2 years. I tried again and drug didn’t work the second time, no help at all. I thought I could keep up the good habits, but when hunger and food noise came back I went back to my old ways. |