Excellent NYT piece about shaming people to take Ozempic, etc for weight loss

[Anonymous]

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Anonymous wrote:I’m not shaming anyone for taking these drugs! I’m just worried that we don’t know enough about the side effects long term.

They have been on the market for many years for diabetics. They’re pretty well understood at this point.

That’s the problem - for diabetes or serious obesity, yeah, the risk of long term side effects may be comparatively less important. The worry is when people start taking them to get down to a BMI of 19. And also the rebound for people who cannot tolerate them.

Okay. What long term side effects in the population are you referring to that are comparatively less important? Specifically

It’s a risk-benefit calculation obviously.

Yes. My question is which risks SPECIFICALLY are you worried about drawing from the data of populations that have already been on the drug many years.

Fen-phen was also on the market for years. Like all new medications, we won’t know until we know. The rebound effect seems pretty clearly established though.

The first Fen-Phen study was published in 1992. It never received FDA approval for obesity. It was banned by 1997.

A minute of googling yeilds a fen-phen paper from 1984: https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/604539

Obviously they are completely different drugs, but there is ample reason to be concerned.

There is whatever reasons to be concerned that you can identify in the copious high quality data we have. What are your specific reasons?

My specific reasons are that Ozempic already has a long list of known side effects and we have *no idea* what will happen with long term use in non-diabetics. You’d frankly have to be an idiot to pretend it’s all sunshine and roses.

But high BP. High cholesterol, diabetes and all of the other problems that come with being obese are? We know there are risks involved. You’d have to be an idiot to assume that we are so dumb as to not know that there are risks with everything you put in your body. Including food!!!!

[Anonymous]

Anonymous wrote:Everybody arguing about the safety of a drug when the article is about the moral superiority of people who are mad people are getting skinny.

Just can’t admit their moral superiority.

I know, right. But they are just so worried for us!! Puhhhleassee

[Anonymous]

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Anonymous wrote:Everybody arguing about the safety of a drug when the article is about the moral superiority of people who are mad people are getting skinny.

Just can’t admit their moral superiority.

I know, right. But they are just so worried for us!! Puhhhleassee

It’s incredibly pathetic. I wonder what happened to these people in their lives that they became this.

[Anonymous]

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Anonymous wrote:I’m not shaming anyone for taking these drugs! I’m just worried that we don’t know enough about the side effects long term.

They have been on the market for many years for diabetics. They’re pretty well understood at this point.

That’s the problem - for diabetes or serious obesity, yeah, the risk of long term side effects may be comparatively less important. The worry is when people start taking them to get down to a BMI of 19. And also the rebound for people who cannot tolerate them.

Okay. What long term side effects in the population are you referring to that are comparatively less important? Specifically

It’s a risk-benefit calculation obviously.

Yes. My question is which risks SPECIFICALLY are you worried about drawing from the data of populations that have already been on the drug many years.

Fen-phen was also on the market for years. Like all new medications, we won’t know until we know. The rebound effect seems pretty clearly established though.

The first Fen-Phen study was published in 1992. It never received FDA approval for obesity. It was banned by 1997.

A minute of googling yeilds a fen-phen paper from 1984: https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/604539

Obviously they are completely different drugs, but there is ample reason to be concerned.

There is whatever reasons to be concerned that you can identify in the copious high quality data we have. What are your specific reasons?

My specific reasons are that Ozempic already has a long list of known side effects and we have *no idea* what will happen with long term use in non-diabetics. You’d frankly have to be an idiot to pretend it’s all sunshine and roses.

Sure we do. The vast majority of Ozempic/Wegovy patients who are taking it for weight loss are obese and therefore on the same spectrum of insulin resistance and metabolic disorder as diabetics, just not as far progressed. Drugs in this class have been on the market for nearly 20 years. Stop fear-mongering.

[Anonymous]

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Anonymous wrote:Yes, some people are furious at the discovery that they aren’t thin because of their moral superiority. It is a blow to their sense of self.

They still haven’t truly accepted this. The drugs work by reducing disproportionate hunger that thinner people do not have. But they really believe it’s doing something else as some sort of cheat code.

It’s not that thinner people aren’t hungry, they just resist the hunger. I have nothing against people using Ozempic and don’t judge them for it, but doesn’t this just prove that it IS about willpower? There’s all this justification that has been used that obesity is due to genetics or hormones or some type of disorder, but a drug that is able to reduce hunger has basically cured all these issues. The problem all along, it seems, is that some people can’t resist the urge to eat. I do think a lot has to do with the American diet (e.g., eating a lot of simple carbs and not enough protein causes insulin crashes that makes people eat more, not enough protein and fiber to suppress hunger), but ultimately it’s all within a person’s control.

My husband and his family are so thin. They eat so much. He got lucky with genes.

[Anonymous]

Anonymous wrote:Who is lying? It’s not a secret that I take it. It is private. I happily tell friends who ask.

This drug is like a miracle to me, and I’ve been through all the diets and losing and gaining so I have some sense of how hard it is or isn’t. And you have to stay on everything “for life” to maintain weight loss so I don’t get the concern.

You’re shamed if you do and shamed if you don’t so whatever.

Good for you! And you don’t have to tell a soul if you don’t want. Screw everyone

[Anonymous]

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Anonymous wrote:

Anonymous wrote:I’m not shaming anyone for taking these drugs! I’m just worried that we don’t know enough about the side effects long term.

They have been on the market for many years for diabetics. They’re pretty well understood at this point.

That’s the problem - for diabetes or serious obesity, yeah, the risk of long term side effects may be comparatively less important. The worry is when people start taking them to get down to a BMI of 19. And also the rebound for people who cannot tolerate them.

Okay. What long term side effects in the population are you referring to that are comparatively less important? Specifically

It’s a risk-benefit calculation obviously.

Yes. My question is which risks SPECIFICALLY are you worried about drawing from the data of populations that have already been on the drug many years.

Fen-phen was also on the market for years. Like all new medications, we won’t know until we know. The rebound effect seems pretty clearly established though.

The first Fen-Phen study was published in 1992. It never received FDA approval for obesity. It was banned by 1997.

A minute of googling yeilds a fen-phen paper from 1984: https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/604539

Obviously they are completely different drugs, but there is ample reason to be concerned.

There is whatever reasons to be concerned that you can identify in the copious high quality data we have. What are your specific reasons?

My specific reasons are that Ozempic already has a long list of known side effects and we have *no idea* what will happen with long term use in non-diabetics. You’d frankly have to be an idiot to pretend it’s all sunshine and roses.

Sure we do. The vast majority of Ozempic/Wegovy patients who are taking it for weight loss are obese and therefore on the same spectrum of insulin resistance and metabolic disorder as diabetics, just not as far progressed. Drugs in this class have been on the market for nearly 20 years. Stop fear-mongering.

Amen!!!! So over the shaming campaign

[Anonymous]

Anonymous wrote:I’m surprised no one here has drawn the analogy to adhd meds. Loooootttsss of people hate on people who take stimulants for not just having the will power to organize their lives. But the medical community is pretty clear that it’s a neuro condition that often requires medication. Pretty similar situation.

This. I have a kid with ADD and I will never truly understand how his brain is wired and you’ll never understand how mine is wired. I have a biologic dysfunction affecting several systems and Mounjaro helps regulate my dysfunction.

The shamers can stay on their moral high ground if it makes them feel worthy and validated. I’ll keep getting healthier and happier.

[Anonymous]

I thought it was fascinating when studies showing thin people who got fecal transplants from heavier people got heavy. Shows that so much of this is biologically driven.

[Anonymous]

I have no problem with anyone taking Ozempic to lose weight. But for the love of God, please stop telling us you lost 75 pounds this last month doing yoga. Please, please stop.

It's ok to admit you have to take drugs to deal with your disorder. It's OKAY.

[Anonymous]

Anonymous wrote:I have no problem with anyone taking Ozempic to lose weight. But for the love of God, please stop telling us you lost 75 pounds this last month doing yoga. Please, please stop.

It's ok to admit you have to take drugs to deal with your disorder. It's OKAY.

This is the fifth time you’ve said the same hyperbolic thing.

Do you have an example of any saying any of this?

The answer is probably no. Because it doesn’t exist.

[Anonymous]

Im on Ozempic and this is truly the first time in my life I havent been controlled by food. I have always thought about food all of the time. What Im eating next, when Im eating. What I can eat to meet whatever calorie goal Im shooting for. I have been binging since elementary school. There was never a feeling of “full”. Diet pills of diff kinds would keep me from eating when I wanted to lose weight, but the obsession w food was always there.

But now, that noise is all gone. I can look at food as more of a bystander vs an addict and make healthy decisions. I can eat a normal amount and get full. I can (for example) eat one piece of candy vs the whole bag.

It is seriously life-changing and I envy those of you have never had a problem with food, and this think fat people just need to have willpower/not eat too much.

[Anonymous]

Who is even taking about this IRL? I could not care less how/why someone lost weight and I don’t ask and don’t want to hear about it. Why do you think thin people care how you lost weight? We don’t

[Anonymous]

Anonymous wrote:Who is even taking about this IRL? I could not care less how/why someone lost weight and I don’t ask and don’t want to hear about it. Why do you think thin people care how you lost weight? We don’t

Ok, do you not notice, with your eyes, your friend who has been fat for several decades, and now has lost 160 pounds???

[Anonymous]

Anonymous wrote:

Anonymous wrote:Who is even taking about this IRL? I could not care less how/why someone lost weight and I don’t ask and don’t want to hear about it. Why do you think thin people care how you lost weight? We don’t

Ok, do you not notice, with your eyes, your friend who has been fat for several decades, and now has lost 160 pounds???

Sometimes, sometimes not. Either way, I don’t inquire about it, and don’t care to know. It isn’t my business if they lost weight due to a drug, diet, cancer, stress, a bypass.