GLP1 Celebrity anorexia - are we going to see deaths?

Anonymous
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Anonymous wrote:No, OP we won't "crack down" on a miracle drug because a few celebrities abused it. Nor should we. You are sick and twisted to be hoping for their deaths so you can gloat that this drug is "bad."


We cracked down on pain killers, why not this? We will have to see the long term side effects before we declare victory over obesity.


Because much to your chagrin, these drugs are extremely helpful and people aren't ruining their lives because of addiction and overdoses. Any other extremely stupid questions?


I mean, you say it won't happen but it already is.

https://www.fda.gov/news-events/press-announcements/fda-intends-take-action-against-non-fda-approved-glp-1-drugs


That is quite different than what the title of this post is. Should FDA crack down on the black market? Maybe. Should the FDA crack down on the use of already approved drugs because a couple of celebrities took it too far? hell no!


The title is not inaccurate. Will we probably see deaths? Yes, we probably will.


Based on what? Your ignorant wishful thinking. You people make me sick.


Um, seeing skeletal people seems more like foregone conclusion. Do you suffer from body dysmorphia?


You're an idiot. I'm sure you're a prolific poster every time GLP drugs are mentioned. You aren't concerned. You wish that the people who need to use GLPs will die. You are the worst or the worst.


The more names you call people the more you invite conversation. People look ill and sick overdoing it on these drugs and calling everyone names who sees it is weird. We all see it whether you ignore it or not.


No one, and I mean NO ONE, gives one single shit about what you think about our use of GLP1s. Yet, you keep blabbing.


You care lots! So keep it up. I've got time.

These scary skinny celebs are ticking time bombs.


I know your parents probably told you that you're smart and special and people like you. They lied. You're just a moron picking fights with people you don't know and salivating over the fact that a celebrity might die. I hope you have the life you deserve.


So what did you weight at your heaviest?


Go back in the hole you came out of.


I'm quite comfy here.


Clearly, you're not. Comfy people don't wish death on strangers. You're a miserable, evil c8nt lashing out at people online because your life sucks.


No one is wishing death on anyone. Why are you overreacting so much?


Why are you incapable of reading? The PP is practically giddy with excitement that some people might die from anorexia (or in her dumb mind because they use GLP1). I’m so sick of pretending that there aren’t actual evil people posting on here.


I’m quite capable of reading and it really seems like you are projecting. You gotta stop taking things so personally. Instead of trying to force people to think the same as you, you need to work on owning your choices and feeling good about who you are.


Do eff off. I am going to call out evil every single time I see it.
Anonymous
Glps don't cause anorexia. People with anorexia shouldn't use them (I am not a dr). They don't cause anorexia.
Anonymous
Anonymous wrote:I can't wait to see what the long term effects of GLP1s are. So far they say there are ongoing nausea, constipation, and diarrhea, gallbladder problems, pancreatitis, and thyroid issues. Some mentioned muscle wasting and neurological problems like anhedonia. Sound fun!


But the thing is these side effects need to be balanced against the well known negative effects on your body of obesity. It’s not appropriate for a normal weight celebrity or average person to be on weight loss drugs (but people are still doing it obviously). But for a person who is morbidly obese or just regular obese … the benefits of losing weight outweigh the risks of constipation/diarrhea, muscle wasting, and gallbladder issues that might pop up. Because obese people tend to struggle with those things more than normal weight people anyway so you might as well be normal weight while you have those problems.
Anonymous
Anonymous wrote:
Anonymous wrote:I can't wait to see what the long term effects of GLP1s are. So far they say there are ongoing nausea, constipation, and diarrhea, gallbladder problems, pancreatitis, and thyroid issues. Some mentioned muscle wasting and neurological problems like anhedonia. Sound fun!


But the thing is these side effects need to be balanced against the well known negative effects on your body of obesity. It’s not appropriate for a normal weight celebrity or average person to be on weight loss drugs (but people are still doing it obviously). But for a person who is morbidly obese or just regular obese … the benefits of losing weight outweigh the risks of constipation/diarrhea, muscle wasting, and gallbladder issues that might pop up. Because obese people tend to struggle with those things more than normal weight people anyway so you might as well be normal weight while you have those problems.


+1

With any medication the risks and benefits are both weighed. Always. Not sure why people are so beyond confused about this, aside from being blinded by hatred of people in larger bodies.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:I can't wait to see what the long term effects of GLP1s are. So far they say there are ongoing nausea, constipation, and diarrhea, gallbladder problems, pancreatitis, and thyroid issues. Some mentioned muscle wasting and neurological problems like anhedonia. Sound fun!


But the thing is these side effects need to be balanced against the well known negative effects on your body of obesity. It’s not appropriate for a normal weight celebrity or average person to be on weight loss drugs (but people are still doing it obviously). But for a person who is morbidly obese or just regular obese … the benefits of losing weight outweigh the risks of constipation/diarrhea, muscle wasting, and gallbladder issues that might pop up. Because obese people tend to struggle with those things more than normal weight people anyway so you might as well be normal weight while you have those problems.


+1

With any medication the risks and benefits are both weighed. Always. Not sure why people are so beyond confused about this, aside from being blinded by hatred of people in larger bodies.


Totally agree.
Anonymous
Then there are studies like this, much to OP's chagrin.

GLP-1 drugs may reduce the risk of cancer progressing, study suggests:

https://www.nbcnews.com/health/cancer/glp-1-drugs-may-reduce-risk-cancer-progressing-study-suggests-rcna346364
Anonymous
Anonymous wrote:
Anonymous wrote:I can't wait to see what the long term effects of GLP1s are. So far they say there are ongoing nausea, constipation, and diarrhea, gallbladder problems, pancreatitis, and thyroid issues. Some mentioned muscle wasting and neurological problems like anhedonia. Sound fun!


But the thing is these side effects need to be balanced against the well known negative effects on your body of obesity. It’s not appropriate for a normal weight celebrity or average person to be on weight loss drugs (but people are still doing it obviously). But for a person who is morbidly obese or just regular obese … the benefits of losing weight outweigh the risks of constipation/diarrhea, muscle wasting, and gallbladder issues that might pop up. Because obese people tend to struggle with those things more than normal weight people anyway so you might as well be normal weight while you have those problems.


Why are you bringing up obesity in a conversation about anorexia?
Anonymous
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Anonymous wrote:There are a number of people in my neighborhood and my office who started ozempic/mounjaro/etc. within the last few years. Here’s what I’ve observed:

The ones who were very overweight and older (50+) are now skeletal and saggy. It’s jarring to see someone lose 100+ pounds. I’ve observed others asking “what’s wrong” or if they have cancer, etc.

The ones who were not very overweight and were just a bit pudgy/flabby got skinny and tighter. They look healthy and just don’t eat much anymore.

I’ve observed most obsessing about their weight and complaining how they just can’t eat much anymore. They seem to struggle to eat half a sandwich.

Every time I go to the GYN the practice asks if I want a consult for a GLP1. I’m 5’9” and hover between 175-180. I’m a size 12/14. I gained 30 pounds when perimenopause started. While I’m tempted to take the magic shot, I can’t get past the feeling that it’s damaging to one’s health.


There's been research, study and testing on these drugs going back as far as the '80's. Trials mandated by the FDA to assess cardiovascular risk showed that the drugs actually have a protective effect against cardiovascular disease.

I'm not saying you should consider using a GLP 1 or not, but through science we already know that a healthy BMI reduces disease risk factors and that these drugs have a positive effect on cardiovascular health. Things like muscle loss can be counteracted with weight lifting, which is recommended for women as part of a healthy lifestyle anyway.


These studies haven’t been done in people without diabetes. What I think we will see is a good deal of osteoporosis, malnutrition and possibly some unexpected outcome regarding pancreatic function in those populations. I don’t have faith in a lot of people to have the discipline necessary to eat that much less and make sure their nutritional needs are being properly met. I hope I’m wrong but I’ve lived long enough and seen enough “miracles” be adopted quickly only to see lots of poor, unexpected and often deadly outcomes.


Are people with diabetes not susceptible to osteoporosis and malnutrition (which seems like an absurd claim)?


No one "claimed" that.

And the dosing is different -- any first year med or pharmacy student can tell you that the only difference between medicine and poison is dose.


The PP claimed exactly that - “ What I think we will see is a good deal of osteoporosis, malnutrition…”

As far as the dose - nice quip, but do you have any evidence that short term higher doses of these medications are poison? Or just vibes?
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:I can't wait to see what the long term effects of GLP1s are. So far they say there are ongoing nausea, constipation, and diarrhea, gallbladder problems, pancreatitis, and thyroid issues. Some mentioned muscle wasting and neurological problems like anhedonia. Sound fun!


But the thing is these side effects need to be balanced against the well known negative effects on your body of obesity. It’s not appropriate for a normal weight celebrity or average person to be on weight loss drugs (but people are still doing it obviously). But for a person who is morbidly obese or just regular obese … the benefits of losing weight outweigh the risks of constipation/diarrhea, muscle wasting, and gallbladder issues that might pop up. Because obese people tend to struggle with those things more than normal weight people anyway so you might as well be normal weight while you have those problems.


Why are you bringing up obesity in a conversation about anorexia?


Because the conversation is about GLP1 medications, which are a treatment for obesity? Not PP, but that seems pretty obvious.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:There are a number of people in my neighborhood and my office who started ozempic/mounjaro/etc. within the last few years. Here’s what I’ve observed:

The ones who were very overweight and older (50+) are now skeletal and saggy. It’s jarring to see someone lose 100+ pounds. I’ve observed others asking “what’s wrong” or if they have cancer, etc.

The ones who were not very overweight and were just a bit pudgy/flabby got skinny and tighter. They look healthy and just don’t eat much anymore.

I’ve observed most obsessing about their weight and complaining how they just can’t eat much anymore. They seem to struggle to eat half a sandwich.

Every time I go to the GYN the practice asks if I want a consult for a GLP1. I’m 5’9” and hover between 175-180. I’m a size 12/14. I gained 30 pounds when perimenopause started. While I’m tempted to take the magic shot, I can’t get past the feeling that it’s damaging to one’s health.


There's been research, study and testing on these drugs going back as far as the '80's. Trials mandated by the FDA to assess cardiovascular risk showed that the drugs actually have a protective effect against cardiovascular disease.

I'm not saying you should consider using a GLP 1 or not, but through science we already know that a healthy BMI reduces disease risk factors and that these drugs have a positive effect on cardiovascular health. Things like muscle loss can be counteracted with weight lifting, which is recommended for women as part of a healthy lifestyle anyway.


These studies haven’t been done in people without diabetes. What I think we will see is a good deal of osteoporosis, malnutrition and possibly some unexpected outcome regarding pancreatic function in those populations. I don’t have faith in a lot of people to have the discipline necessary to eat that much less and make sure their nutritional needs are being properly met. I hope I’m wrong but I’ve lived long enough and seen enough “miracles” be adopted quickly only to see lots of poor, unexpected and often deadly outcomes.


Are people with diabetes not susceptible to osteoporosis and malnutrition (which seems like an absurd claim)?


No one "claimed" that.

And the dosing is different -- any first year med or pharmacy student can tell you that the only difference between medicine and poison is dose.


The PP claimed exactly that - “ What I think we will see is a good deal of osteoporosis, malnutrition…”

As far as the dose - nice quip, but do you have any evidence that short term higher doses of these medications are poison? Or just vibes?


It's more than a nice "quip." And none of it was "vibes." Move along.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:There are a number of people in my neighborhood and my office who started ozempic/mounjaro/etc. within the last few years. Here’s what I’ve observed:

The ones who were very overweight and older (50+) are now skeletal and saggy. It’s jarring to see someone lose 100+ pounds. I’ve observed others asking “what’s wrong” or if they have cancer, etc.

The ones who were not very overweight and were just a bit pudgy/flabby got skinny and tighter. They look healthy and just don’t eat much anymore.

I’ve observed most obsessing about their weight and complaining how they just can’t eat much anymore. They seem to struggle to eat half a sandwich.

Every time I go to the GYN the practice asks if I want a consult for a GLP1. I’m 5’9” and hover between 175-180. I’m a size 12/14. I gained 30 pounds when perimenopause started. While I’m tempted to take the magic shot, I can’t get past the feeling that it’s damaging to one’s health.


There's been research, study and testing on these drugs going back as far as the '80's. Trials mandated by the FDA to assess cardiovascular risk showed that the drugs actually have a protective effect against cardiovascular disease.

I'm not saying you should consider using a GLP 1 or not, but through science we already know that a healthy BMI reduces disease risk factors and that these drugs have a positive effect on cardiovascular health. Things like muscle loss can be counteracted with weight lifting, which is recommended for women as part of a healthy lifestyle anyway.


These studies haven’t been done in people without diabetes. What I think we will see is a good deal of osteoporosis, malnutrition and possibly some unexpected outcome regarding pancreatic function in those populations. I don’t have faith in a lot of people to have the discipline necessary to eat that much less and make sure their nutritional needs are being properly met. I hope I’m wrong but I’ve lived long enough and seen enough “miracles” be adopted quickly only to see lots of poor, unexpected and often deadly outcomes.


Are people with diabetes not susceptible to osteoporosis and malnutrition (which seems like an absurd claim)?


No one "claimed" that.

And the dosing is different -- any first year med or pharmacy student can tell you that the only difference between medicine and poison is dose.


The PP claimed exactly that - “ What I think we will see is a good deal of osteoporosis, malnutrition…”

As far as the dose - nice quip, but do you have any evidence that short term higher doses of these medications are poison? Or just vibes?


It's more than a nice "quip." And none of it was "vibes." Move along.


DP. So you can’t support your dumb claims. That tracks.
Anonymous
Anonymous wrote:Then there are studies like this, much to OP's chagrin.

GLP-1 drugs may reduce the risk of cancer progressing, study suggests:

https://www.nbcnews.com/health/cancer/glp-1-drugs-may-reduce-risk-cancer-progressing-study-suggests-rcna346364


Why would that bother Op? You seem to be super defensive. I think everyone would be glad about that. Celebrities misusing a medication is a real thing. It is a bad thing because it influences others. Urging caution when talking about using a drug in a new way for life is a real thing that should be considered. It’s like this board is filled with teenagers .
Anonymous
Anonymous wrote:
Anonymous wrote:Ryan Seacrest looks horrible.


I'm sure he will be devastated that you think so.


He sure will.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:There are a number of people in my neighborhood and my office who started ozempic/mounjaro/etc. within the last few years. Here’s what I’ve observed:

The ones who were very overweight and older (50+) are now skeletal and saggy. It’s jarring to see someone lose 100+ pounds. I’ve observed others asking “what’s wrong” or if they have cancer, etc.

The ones who were not very overweight and were just a bit pudgy/flabby got skinny and tighter. They look healthy and just don’t eat much anymore.

I’ve observed most obsessing about their weight and complaining how they just can’t eat much anymore. They seem to struggle to eat half a sandwich.

Every time I go to the GYN the practice asks if I want a consult for a GLP1. I’m 5’9” and hover between 175-180. I’m a size 12/14. I gained 30 pounds when perimenopause started. While I’m tempted to take the magic shot, I can’t get past the feeling that it’s damaging to one’s health.


There's been research, study and testing on these drugs going back as far as the '80's. Trials mandated by the FDA to assess cardiovascular risk showed that the drugs actually have a protective effect against cardiovascular disease.

I'm not saying you should consider using a GLP 1 or not, but through science we already know that a healthy BMI reduces disease risk factors and that these drugs have a positive effect on cardiovascular health. Things like muscle loss can be counteracted with weight lifting, which is recommended for women as part of a healthy lifestyle anyway.


These studies haven’t been done in people without diabetes. What I think we will see is a good deal of osteoporosis, malnutrition and possibly some unexpected outcome regarding pancreatic function in those populations. I don’t have faith in a lot of people to have the discipline necessary to eat that much less and make sure their nutritional needs are being properly met. I hope I’m wrong but I’ve lived long enough and seen enough “miracles” be adopted quickly only to see lots of poor, unexpected and often deadly outcomes.


Are people with diabetes not susceptible to osteoporosis and malnutrition (which seems like an absurd claim)?


No one "claimed" that.

And the dosing is different -- any first year med or pharmacy student can tell you that the only difference between medicine and poison is dose.


The PP claimed exactly that - “ What I think we will see is a good deal of osteoporosis, malnutrition…”

As far as the dose - nice quip, but do you have any evidence that short term higher doses of these medications are poison? Or just vibes?


It's more than a nice "quip." And none of it was "vibes." Move along.


DP. So you can’t support your dumb claims. That tracks.


You aren't one for logic. That tracks.
Anonymous
I am an eating disorder therapist. I haven't read through every comment, but have a few thoughts.

Simple weight loss (whether from a GLP-1, dieting or inadvertent) can trigger an eating disorder in *some* people. Most people who lose weight do not develop anorexia, but some do and it's usually because of a number of biological, psychological and social factors. So while lots of people are using GLP-1s for weight loss, only some will go on to develop an ED. So without knowing Kelly Osbourne or Demi Moore, I'd venture to guess that they both had some history of disordered eating that was re-triggered by their weight loss and now things have spun out of control

I have had patients with anorexia use GLP-1s because they think that it will quiet the constant food noise that they experience. My dream is one day for there to be a GLP-1 type of med that has the psychological benefits without the appetite suppressant.

Before I did this work, I was so flippant about eating disorders, but anorexia is a horrible disease. It is no way to live and the quality of life is abysmal. It can rob a person of everything they care about. I truly hope that these celebrities, and anyone else suffering, can get good treatment. People can recover with good treatment, but it takes a lot of work and it's not an easy road.
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