Covid vaccine and menstruation

Anonymous
Another article on this phenomenon, and this one poses two potential hypotheses that explain why this could be happening:

https://tarahaelle.medium.com/lack-of-data-on-covid-19-vaccines-and-periods-inspired-two-feminist-scientists-to-learn-more-b4c29395fb5

“ Exploring possible mechanisms
Jen Gunther, an OBGYN who writes The Vajenda at Substack, took a deep dive into the possible mechanisms that might explain a link between Covid-19 vaccination and menstruation if it does turn out that there’s an association — something that hasn’t yet been shown conclusively. She also expressed frustration at how women’s issues are often ignored, and her discussion of biology is well worth the read.
Clancy mentioned two potential biological mechanisms that she’s aware of. One came from her discussions with Anirban Sen Gupta, PhD, a platelet researcher at Case Western Reserve University who will be collaborating with Lee and Clancy.
Sen Gupta told Clancy that some research has a possible link between the nanoparticles used in the mRNA vaccines and a temporary reduction in platelets count. Platelets are the blood cells that help blood clot, so it’s possible that fewer platelets could lead to heavier bleeding — less clotting — in someone having a period, Clancy said.
“If you’re a menstruator and your period is due soon anyway, then you might kind of have some kind of bleeding event that is much more powerful than what you would normally have just because your body is not quite as effective as at coagulating your blood,” she said.
The phenomenon of lower platelet counts is called thrombocytopenia, and it is already a known rare side effect of the measles-mumps-rubella (MMR) vaccine. The condition is not life-threatening and resolves on its own without any long-term side effects. Clancy emphasized that it’s important that people don’t worry that heavier bleeding after a vaccine suggests any concerns about fertility or other systemic issues.
Another possible mechanism is the normal immune activation that occurs as a result of a vaccine,” Clancy said. Her lab has previously studied how systematic inflammation can be associated with changes in hormone concentrations and other temporary effects on the reproductive system. Inflammation essentially refers to the immune system taking notice of a perceived threat and responding to it. Clancy’s lab has found that people with higher levels of C-reactive protein (CRP), a biomarker for inflammation, tend to have lower levels of estradiol and progesterone concentrations.
“What we could be seeing here is, again, another transient response to your immune system getting a pretty good kick,” Clancy said. “A vaccine is activating your immune system. It’s going to create some inflammation.”
The uterus might be particularly sensitive to temporary inflammation because it’s such a dynamic environment.
“The thing that’s so cool about the uterus is that it’s a site for where tons and tons of tissue remodeling is happening all the time,” Clancy said. “It’s constantly making new tissue and constantly differentiating tissue. So if you have some other major inflammatory thing happening in the body, you can imagine it might mess with some with some tissue remodeling.””
Anonymous
Anonymous wrote:
Anonymous wrote:Did the trials not include many pre-menopausal women? I've heard so many stories about period-related side effects.


Only those on birth control, so nobody on natural cycles. I assume it's because they didn't want women in the trial to get pregnant, but it sure is a major flaw in the trial.




Understatement of the year.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:Did the trials not include many pre-menopausal women? I've heard so many stories about period-related side effects.


Only those on birth control, so nobody on natural cycles. I assume it's because they didn't want women in the trial to get pregnant, but it sure is a major flaw in the trial.




Understatement of the year.


Well, it’s apparently standard protocol for vaccine trials
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:Did the trials not include many pre-menopausal women? I've heard so many stories about period-related side effects.


Only those on birth control, so nobody on natural cycles. I assume it's because they didn't want women in the trial to get pregnant, but it sure is a major flaw in the trial.




Understatement of the year.


Well, it’s apparently standard protocol for vaccine trials


Which is maybe kind of a problem, no? I mean, it was only in the 1990’s that women were required to be included in clinical trials at all. The 90’s!
Anonymous
Anonymous wrote:Another article on this phenomenon, and this one poses two potential hypotheses that explain why this could be happening:

https://tarahaelle.medium.com/lack-of-data-on-covid-19-vaccines-and-periods-inspired-two-feminist-scientists-to-learn-more-b4c29395fb5



Thank you for this article. It's helpful and reassuring.
Anonymous
is this serious enough that we shouldn’t be getting the vaccine?
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:Did the trials not include many pre-menopausal women? I've heard so many stories about period-related side effects.


Only those on birth control, so nobody on natural cycles. I assume it's because they didn't want women in the trial to get pregnant, but it sure is a major flaw in the trial.




Understatement of the year.


Well, it’s apparently standard protocol for vaccine trials


Which is maybe kind of a problem, no? I mean, it was only in the 1990’s that women were required to be included in clinical trials at all. The 90’s!

Oh, I 100% agree. I was one of the people screaming from the rafters trying to get attention to this issue and someone to finally look into it. I couldn’t be more thrilled that it is now getting the attention it deserves but agree that this shouldn’t be the default rule for female participation in studies precisely to avoid these types of surprises (potentially - who knows if it would’ve come up in the trial had they not had this rule but it would certainly make me feel better about things had they not had this limitation!). I simply meant that there wasn’t anything unique about these trials to make them less trustworthy. This is just (unfortunately) how such trials are done
Anonymous
I had terrible back cramps a week before my period post first dose of the vaccine. I mean terrible. I could barely walk. I usually have back cramps but these were significantly worse. After a few days- back to normal. And normal period otherwise. No other explanation for such a significant deviation from my normal period. (I am not on birth control)
Anonymous
I have no idea to link to it here, but there’s a good article in The Verge on this issue and the Kate Clancy study. Personally, I’ve had both doses of Pfizer with no incident and I’m a huge proponent of these vaccines BUT 1) I do think that women’s issues and menstrual issues are often overlooked by medicine in general and 2) if I had really weird symptoms it would freak me out so I understand the concern.

I do think we need to remember that millions and millions have received these vaccines and done number of women are going to coincidentally have weird cycles or other underlying issues crop up so they likely aren’t all related.

The Verge article raises two possibilities, immune system response and that the nanoparticles in the vaccine are affecting clotting function. The good new is that there doesn’t seem to be any indication that fertility is impacted which is what a lot of people seem worried about.
Anonymous
Anonymous wrote:Another article on this phenomenon, and this one poses two potential hypotheses that explain why this could be happening:

https://tarahaelle.medium.com/lack-of-data-on-covid-19-vaccines-and-periods-inspired-two-feminist-scientists-to-learn-more-b4c29395fb5


The Jen Gunter article that's referenced in this one is definitely worth a read. Very thorough, level-headed assessment of possible causes.

https://vajenda.substack.com/p/the-covid-19-vaccine-and-menstrual

I just got my first Pfizer dose today and am planning to participate in the Clancy study (linked at the end of Gunter's article, also). I'm so glad this issue is gaining some attention!
Anonymous
I got Pfizer and my period started like clockwork (30 day cycle). It did seem heavier than usual and a day longer.
Anonymous
Dr. Michael Yeadon (scientist and former Pfizer VP), along with a coalition of other scientists, filed legal petitions with the FDA and EMA (European equivalent) in December urging them not to approve the vaccines until further research was done w/r/t several issues. One of the issues was how the vaccine mechanism would adversely affect a woman's ability to form and maintain a placenta. He went into detail regarding the scientific basis for his concern. While I'm not a scientist, it seemed like sound reasoning to me, but obviously his warning was not heeded by either agency. He also warned about the anaphylaxis and blood clotting issues, so it seems like he knows enough to be taken seriously at least.
Hearing all of the accounts on this thread makes me think of Dr. Yeadon's concerns because menstruation is essentially the shedding of the uterine lining (a potential placenta). It would be interesting to find out the difference between the rate of miscarriages pre-Dec2020 vs post-Dec2020.
Anonymous
Anonymous wrote:Dr. Michael Yeadon (scientist and former Pfizer VP), along with a coalition of other scientists, filed legal petitions with the FDA and EMA (European equivalent) in December urging them not to approve the vaccines until further research was done w/r/t several issues. One of the issues was how the vaccine mechanism would adversely affect a woman's ability to form and maintain a placenta. He went into detail regarding the scientific basis for his concern. While I'm not a scientist, it seemed like sound reasoning to me, but obviously his warning was not heeded by either agency. He also warned about the anaphylaxis and blood clotting issues, so it seems like he knows enough to be taken seriously at least.
Hearing all of the accounts on this thread makes me think of Dr. Yeadon's concerns because menstruation is essentially the shedding of the uterine lining (a potential placenta). It would be interesting to find out the difference between the rate of miscarriages pre-Dec2020 vs post-Dec2020.


There's absolutely zero difference in miscarriages. Stop trying to scare people into becoming an anti-vaxxer like you!
Anonymous
I'm not trying to scare anyone, and I'm not an anti-vaxxer. My family and I are up-to-date on all of our shots. My husband and I even got the pfizer covid vaccine. Why can't people talk about real, rational concerns about the vaccine without being ostracized? I feel like I'm living in the twilight zone. Also, how could you possibly know there's zero change in miscarriage rates?
Anonymous
Anonymous wrote:is this serious enough that we shouldn’t be getting the vaccine?




Only you can determined the risk/benefit of getting it. Long term outcomes are not known, but that isn't stopping millions of people from getting the shot. The m rnas were never an option for me and now J&J is off the table, too.
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