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Reply to "Covid vaccine and menstruation"
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[quote=Anonymous]Another article on this phenomenon, and this one poses two potential hypotheses that explain why this could be happening: https://tarahaelle.medium.com/lack-of-data-on-covid-19-vaccines-and-periods-inspired-two-feminist-scientists-to-learn-more-b4c29395fb5 “ Exploring possible mechanisms Jen Gunther, an OBGYN who writes The Vajenda at Substack, took a deep dive into the possible mechanisms that might explain a link between Covid-19 vaccination and menstruation if it does turn out that there’s an association — something that hasn’t yet been shown conclusively. She also expressed frustration at how women’s issues are often ignored, and her discussion of biology is well worth the read. Clancy mentioned two potential biological mechanisms that she’s aware of. One came from her discussions with Anirban Sen Gupta, PhD, a platelet researcher at Case Western Reserve University who will be collaborating with Lee and Clancy. Sen Gupta told Clancy that some research has a possible link between the nanoparticles used in the mRNA vaccines and a temporary reduction in platelets count. Platelets are the blood cells that help blood clot, so it’s possible that fewer platelets could lead to heavier bleeding — less clotting — in someone having a period, Clancy said. “If you’re a menstruator and your period is due soon anyway, then you might kind of have some kind of bleeding event that is much more powerful than what you would normally have just because your body is not quite as effective as at coagulating your blood,” she said. The phenomenon of lower platelet counts is called thrombocytopenia, and it is already a known rare side effect of the measles-mumps-rubella (MMR) vaccine. The condition is not life-threatening and resolves on its own without any long-term side effects. Clancy emphasized that it’s important that people don’t worry that heavier bleeding after a vaccine suggests any concerns about fertility or other systemic issues. Another possible mechanism is the normal immune activation that occurs as a result of a vaccine,” Clancy said. Her lab has previously studied how systematic inflammation can be associated with changes in hormone concentrations and other temporary effects on the reproductive system. Inflammation essentially refers to the immune system taking notice of a perceived threat and responding to it. Clancy’s lab has found that people with higher levels of C-reactive protein (CRP), a biomarker for inflammation, tend to have lower levels of estradiol and progesterone concentrations. “What we could be seeing here is, again, another transient response to your immune system getting a pretty good kick,” Clancy said. “A vaccine is activating your immune system. It’s going to create some inflammation.” The uterus might be particularly sensitive to temporary inflammation because it’s such a dynamic environment. “The thing that’s so cool about the uterus is that it’s a site for where tons and tons of tissue remodeling is happening all the time,” Clancy said. “It’s constantly making new tissue and constantly differentiating tissue. So if you have some other major inflammatory thing happening in the body, you can imagine it might mess with some with some tissue remodeling.””[/quote]
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