Mayim Bialik's horrific experience on GLP-1's

[Anonymous]

Anonymous wrote:

Anonymous wrote:Mayim Biyalik is a nut job.

She has a PhD in neuroscience from UCLA.

DP. She was touting a supplement for "brain health." So, yeah, I think I will consider her ethics and science questionable.

https://sciencebasedmedicine.org/mayim-bialiks-neuriva-commercials-make-questionable-claims/

[Anonymous]

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Anonymous wrote:

Anonymous wrote:I find it fascinating how over the top the reactions are to this. Like OP has insulted your mother and you must come to her defense. So much anger and disdain. It's weird.

Oh hey OP. Glad to see you're back.

I consider it infinitely weirder to post for the 247th time about something that doesn't concern you at all. Thanks!

How does this concern you?

I have been taking Ozempic for five years now. Very few side effects, monitored by my doctor, brought my cholesterol, triglycerides, A1C and BP back down to normal. Any other questions I can answer for you?

How nice. But you're not the only one allowed to comment or discuss.

Did I preclude anyone from commenting? Comment away and I'll say what I want to say in response.

How does someone talking about Mayim's experience concern you? It doesn't. So get used to seeing posts like this.

No, I don't think I will. I will point out how dumb and idiotic it is each and every time I see posts like this. Get used to it.

Oh, I will. I enjoy these threads and how worked up you get.

I defend drugs with pesky facts. It doesn't matter if I've used them or not. Drugs are great. This one has extended and improved millions of lives world wide over two decades. #winning

I will still read about the negative experiences the way I read bad hotel or restaurant reviews. I take all the rave review with a grain of salt.

[Anonymous]

Anonymous wrote:Ugh. I already have bowel incontinence from ibs when I’m about to get my period and if I drink coffee or eat too much fiber. Like fruit or veg. It’s no fun. It has happened at work. I practically had to make a stealthy escape with no underwear. No fun. I do have prediabetes but only take metformin. I can’t imagine getting worse in the bowels department.

I had similarly bad IBS-D. Been on Zepbound for 4 months and I have had much much more normal bowel movements. Far fewer instances of extreme urgency and diarrhea. My doc has seen similar changes in others with severe IBS-D because of how GLP-1s slow digestion.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Ugh. I already have bowel incontinence from ibs when I’m about to get my period and if I drink coffee or eat too much fiber. Like fruit or veg. It’s no fun. It has happened at work. I practically had to make a stealthy escape with no underwear. No fun. I do have prediabetes but only take metformin. I can’t imagine getting worse in the bowels department.

I had similarly bad IBS-D. Been on Zepbound for 4 months and I have had much much more normal bowel movements. Far fewer instances of extreme urgency and diarrhea. My doc has seen similar changes in others with severe IBS-D because of how GLP-1s slow digestion.

Metformin is known for causing bowel issues- you were counseled about that correct? ER form still causes issues but is better tolerated.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

Not only the drugs but the gastric bypass and bands didn't work either. Bodies adapt and we'll likely see this with the drugs over time. Then we'll be on to the next craze.

My friend got a gastric sleeve in Tijuana. She lost 20 pounds in the first 3 months. She began consuming milk shakes, ice cream and other calorie laden foods which overrode her surgery. Within a year of her surgery, she basically stretched her stomach back out (or something), resumed her previous overeating habits, regained the weight lost and added 20 pounds more. Moral: people will do anything, other than address the core reasons for their overeating (which is evidenced by their relentless "food noise") to lose weight. Sadly, without significant habit changes, lifestyle changes and psychological growth, the WEIGHT ALWAYS COMES BACK.

Weight virtually always comes back regardless of lifestyle changes. 90-95% who have lost significant weight gain all or more than all of it back within 5 years.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I find it fascinating how over the top the reactions are to this. Like OP has insulted your mother and you must come to her defense. So much anger and disdain. It's weird.

Oh hey OP. Glad to see you're back.

I consider it infinitely weirder to post for the 247th time about something that doesn't concern you at all. Thanks!

How does this concern you?

That's fire but I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE nor the NHS in UK. R

I have been taking Ozempic for five years now. Very few side effects, monitored by my doctor, brought my cholesterol, triglycerides, A1C and BP back down to normal. Any other questions I can answer for you?

How nice. But you're not the only one allowed to comment or discuss.

Did I preclude anyone from commenting? Comment away and I'll say what I want to say in response.

How does someone talking about Mayim's experience concern you? It doesn't. So get used to seeing posts like this.

No, I don't think I will. I will point out how dumb and idiotic it is each and every time I see posts like this. Get used to it.

Oh, I will. I enjoy these threads and how worked up you get.

I defend drugs with pesky facts. It doesn't matter if I've used them or not. Drugs are great. This one has extended and improved millions of lives world wide over two decades. #winning

I will still read about the negative experiences the way I read bad hotel or restaurant reviews. I take all the rave review with a grain of salt.

That's fine. I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE or the NHS in UK. Really whatever they think is a good source of info on meds.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I find it fascinating how over the top the reactions are to this. Like OP has insulted your mother and you must come to her defense. So much anger and disdain. It's weird.

Oh hey OP. Glad to see you're back.

I consider it infinitely weirder to post for the 247th time about something that doesn't concern you at all. Thanks!

How does this concern you?

That's fire but I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE nor the NHS in UK. R

I have been taking Ozempic for five years now. Very few side effects, monitored by my doctor, brought my cholesterol, triglycerides, A1C and BP back down to normal. Any other questions I can answer for you?

How nice. But you're not the only one allowed to comment or discuss.

Did I preclude anyone from commenting? Comment away and I'll say what I want to say in response.

How does someone talking about Mayim's experience concern you? It doesn't. So get used to seeing posts like this.

No, I don't think I will. I will point out how dumb and idiotic it is each and every time I see posts like this. Get used to it.

Oh, I will. I enjoy these threads and how worked up you get.

I defend drugs with pesky facts. It doesn't matter if I've used them or not. Drugs are great. This one has extended and improved millions of lives world wide over two decades. #winning

I will still read about the negative experiences the way I read bad hotel or restaurant reviews. I take all the rave review with a grain of salt.

That's fine. I usually use citations when defending drugs but this one is so old they can just wiki it. Or look at NICE or the NHS in UK. Really whatever they think is a good source of info on meds.

I'm not looking at random posters to "defend drugs" I can do that on my own time what I am interested is other's experiences. It's a conversation and people can take it or leave it. But trying to halt the discussion and shut it down is weird. What are people so afraid of?

[Anonymous]

Anonymous wrote:

Anonymous wrote:It is not surprising that some people have a severe reaction to GLP-1 medication, especially someone like Mayim Bialik who reports a very long list of autoimmune conditions. My feeling is that if I get a severe reaction to GLP-1, then I'll stop taking it.

But I was surprised to read her say that a single shot of the lowest dose GLP-1 caused "a full month of alternating diarrhea and constipation". I am skeptical of how much drug could still be present in her body after a month. I suspect that she already had an autoimmune gastrointestinal illness.

Where did you get your medical degree from? I bet you take this and have no clue as to the very long half life of this medication. So ignorant. But at least you're skinny now right? That's all that matters.

What do you think is the half-life of GLP-1 medication? Hint: Why do you think people take weekly doses?

[Anonymous]

Anonymous wrote:

Anonymous wrote:Mayim Biyalik is a nut job.

She has a PhD in neuroscience from UCLA.

And Dr. Oz is a heart surgeon.

I take a GLP-1 and took it to lose 15-20 lbs. zero side effects, but I “microdose.” I get it from midi. My dr knows and is fine with it. I feel amazing on it. I plan to take it indefinitely.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Mayim Biyalik is a nut job.

She has a PhD in neuroscience from UCLA.

And Dr. Oz is a heart surgeon.

I take a GLP-1 and took it to lose 15-20 lbs. zero side effects, but I “microdose.” I get it from midi. My dr knows and is fine with it. I feel amazing on it. I plan to take it indefinitely.

If doctor is ok with it, why are they not the prescriber?

[Anonymous]

Anonymous wrote:

Anonymous wrote:Mayim Biyalik is a nut job.

She has a PhD in neuroscience from UCLA.

So what? The NIH director is an MD/PhD yet here we are.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

Not only the drugs but the gastric bypass and bands didn't work either. Bodies adapt and we'll likely see this with the drugs over time. Then we'll be on to the next craze.

My friend got a gastric sleeve in Tijuana. She lost 20 pounds in the first 3 months. She began consuming milk shakes, ice cream and other calorie laden foods which overrode her surgery. Within a year of her surgery, she basically stretched her stomach back out (or something), resumed her previous overeating habits, regained the weight lost and added 20 pounds more. Moral: people will do anything, other than address the core reasons for their overeating (which is evidenced by their relentless "food noise") to lose weight. Sadly, without significant habit changes, lifestyle changes and psychological growth, the WEIGHT ALWAYS COMES BACK.

Weight virtually always comes back regardless of lifestyle changes. 90-95% who have lost significant weight gain all or more than all of it back within 5 years.

This. If I'm going to lose and regain all my weight, I'd rather do it through healthy eating than deal with the side effects and mess up my GI system.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

Not only the drugs but the gastric bypass and bands didn't work either. Bodies adapt and we'll likely see this with the drugs over time. Then we'll be on to the next craze.

My friend got a gastric sleeve in Tijuana. She lost 20 pounds in the first 3 months. She began consuming milk shakes, ice cream and other calorie laden foods which overrode her surgery. Within a year of her surgery, she basically stretched her stomach back out (or something), resumed her previous overeating habits, regained the weight lost and added 20 pounds more. Moral: people will do anything, other than address the core reasons for their overeating (which is evidenced by their relentless "food noise") to lose weight. Sadly, without significant habit changes, lifestyle changes and psychological growth, the WEIGHT ALWAYS COMES BACK.

Weight virtually always comes back regardless of lifestyle changes. 90-95% who have lost significant weight gain all or more than all of it back within 5 years.

This. If I'm going to lose and regain all my weight, I'd rather do it through healthy eating than deal with the side effects and mess up my GI system.

Or you could do it in a more effective way that takes less effort, has a way higher level of success, and for 50% of people has 0 side effects. I’m not pushing GLP-1s at all (I don’t care how you do or don’t lose weight), but most people experience no side effects at all, and the vast majority experience only mild side effects. I for one have experienced plenty of side effects from natural weight loss, including dizziness, brain fog, fatigue, coldness, and decreased sex drive.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs.

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight.

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.

Same. I'm not overweight nor diabetic and have no need to be a guinea pig. Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.

Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.

Not only the drugs but the gastric bypass and bands didn't work either. Bodies adapt and we'll likely see this with the drugs over time. Then we'll be on to the next craze.

My friend got a gastric sleeve in Tijuana. She lost 20 pounds in the first 3 months. She began consuming milk shakes, ice cream and other calorie laden foods which overrode her surgery. Within a year of her surgery, she basically stretched her stomach back out (or something), resumed her previous overeating habits, regained the weight lost and added 20 pounds more. Moral: people will do anything, other than address the core reasons for their overeating (which is evidenced by their relentless "food noise") to lose weight. Sadly, without significant habit changes, lifestyle changes and psychological growth, the WEIGHT ALWAYS COMES BACK.

Weight virtually always comes back regardless of lifestyle changes. 90-95% who have lost significant weight gain all or more than all of it back within 5 years.

This. If I'm going to lose and regain all my weight, I'd rather do it through healthy eating than deal with the side effects and mess up my GI system.

Or you could do it in a more effective way that takes less effort, has a way higher level of success, and for 50% of people has 0 side effects. I’m not pushing GLP-1s at all (I don’t care how you do or don’t lose weight), but most people experience no side effects at all, and the vast majority experience only mild side effects. I for one have experienced plenty of side effects from natural weight loss, including dizziness, brain fog, fatigue, coldness, and decreased sex drive.

PP. I don't begrudge you or anyone else taking them. I am just not comfortable with the potential of messing with the GI system and the fact that I will gain it all back if I stop taking them (which I have done before, without drugs). I feel like the world judges me for not taking them just like it judges other people for taking them.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:First she's a nut job and second this is true of all meds. Some people don't tolerate certain drugs. Nothing to see here.

Exactly. The page of small prints comes with every medication? It lists every bad reaction happened to someone, even if it was less than one in a million. Should we ban all medications?

I don't think anyone is saying ban, just weigh the risks.

So, you mean, consult with your physician before starting a medication (which has to be prescribed by a doctor)?

Well yeah, if it's a real consult, where if your doctor tells you that your labs are good and you don't need the medication, you're willing to accept that.

Interestingly, it was my NP who brought it up to me at 2 different annual physicals 1 year apart. My bmi was like 25.5 and only going up.

This didn’t happen. No medical professional is going to push these on you for a BMI of 25 unless your labs are horrible. The people using it at that BMI are using compounded versions that contain - well who the hell knows - in them. That should be the bigger concern, not using the actual prescriptions, but the compounded versions that aren’t as regulated.