Friend who works in pharma went on a rant about how bad Ozempic etc is for people. ?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

PP you replied to. I say this very seriously. No drug is a miracle drug. Even penicillin, which saved millions of lives immediately when it put on the market before WWII.

Of course antibiotics have side effects but to act like penicillin was not a miracle drug, insanity. Cuts used to be potentially life threatening!

[Anonymous]

Anonymous wrote:self-control. People like people that have self-control and self-regulation.

But apparently can't write.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

This won't play out for many, many reasons...
1) we are not treating the root of the problem which is our sedentary lifestyle and our food supply
2) corporations and the people who get rich running them have a vested interest in keeping cheetohs and coke as part of our diet
3) human nature is to want this "quick fix" because we have evolved to conserve energy and consume as much energy as we can
4) we are more disconnected than ever because of social media and letting our "leaders" divide us in the interest of lining their own pockets
5) cars and Americans' obsession with big, plastic houses and big, dangerous cars
6) we still need to sell our soul to the company store just for health insurance
7) legalization and cultural acceptance of more and more recreational drugs

I lost 70 lbs on Ozmepic and completely changed what I ate and also exercised like crazy. It just allowed me to do those things without feeling completely deprived all the time. Stop spewing nonsense about quick fixes. Nothing quick or easy about it. I did the work but Ozempic helped greatly.

[Anonymous]

Ozempic is not without risks. Specifically, it dramatically slows digestion, which can cause dangerous constipation that can lead to necrosis. It should be used with caution for anyone with a compromised GI system. This has been slow-rolled by the pharma companies and kind of buried.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

The verdict is in. The lab rats have already been under scrutiny for many many years as this drug has already been in use. The fact that it is being used more widely now is really the only difference – most of the people going on it are already verging close enough to being Diabetic that the difference is almost negligible. Stop hating people because they’re fat and wish them luck on their journey.

[Anonymous]

Anonymous wrote:Ozempic is not without risks. Specifically, it dramatically slows digestion, which can cause dangerous constipation that can lead to necrosis. It should be used with caution for anyone with a compromised GI system. This has been slow-rolled by the pharma companies and kind of buried.

No one hasn’t. It’s on literally every chat board and it is the biggest wording that they give you about taking these drugs. I’ve been taking them since August and take daily fiber, I tracked my fiber intake through food, I eat several small meals a day there are a mix of grains veggies, and very lean protein, and I have had zero problems. I’m on an extremely low dose and it is finally helping me see results of all my workouts and healthy eating. You have no idea what so many of us have gone through to get to this point.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

Not all people are the same.
You can be fit and fat.
Fat also increases some risks like diabetes.

Everyone including ops friend should myob

There is not a single objective health measure that improves by carrying excessive body fat other than being dramatically underweight. That's reality.

Reality is that you and the rest of the fatphobes on this forum/in this culture don't give a rat's behind about a fat stranger's health. Fat bodies are an acceptable target for your concern trolling, othering, and ableism. That's it. You hide behind "health concerns" but if you really gave a damn about a stranger's health, you wouldn't lead by insulting their intelligence, framing yourself as superior because you wear a smaller size, and then treating them like a hapless idiot who needs your help or your opinion.

Being judged for existing in the body you've got isn't good for anyone's health, doesn't motivate people to change their body shape, and can actively harm people to the point of suicidal ideation and self-harm.

There's not a single objective health measure that improves by being judged by a stranger. THAT is reality, so STFU.

You might consider that when you quote a post, the prior discussion was included.

If you bothered reading, you would find I was responding to the notion that fitness and being fat can coexist. That’s just not true. In extremely rare cases people with an obese BMI may not be carrying around significant body fat far in excess of what’s healthy. That’s not the 99.9% of Americans in the obese category. That’s what I was responding to that caused you to get all butt hurt.

So no, there is not a single objective health measure that improves by carrying around excess body fat. Maybe go work on that instead of being butt hurt by people pointing out facts. Facts aren’t judgement - you just turn them into something about you because you don’t like general facts. Maybe also work on that while you are at it.

So you're an idiot, as well as an ass? Cool. Thanks for the information.

You are free to explain how there IS a single objective health measure that improves by carrying around excess body fat.

YES!!!! End of story!!

[Anonymous]

Anonymous wrote:Ozempic is not without risks. Specifically, it dramatically slows digestion, which can cause dangerous constipation that can lead to necrosis. It should be used with caution for anyone with a compromised GI system. This has been slow-rolled by the pharma companies and kind of buried.

I normally have the best transit system (perfect poops, every am, zero GI issues ever) and thought I was going to die from constipation on Ozempic. It was the worst pain of my life.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Ozempic is not without risks. Specifically, it dramatically slows digestion, which can cause dangerous constipation that can lead to necrosis. It should be used with caution for anyone with a compromised GI system. This has been slow-rolled by the pharma companies and kind of buried.

I normally have the best transit system (perfect poops, every am, zero GI issues ever) and thought I was going to die from constipation on Ozempic. It was the worst pain of my life.

I've had IBS my whole life basically and love that I don't have constant diarrhea on Ozempic. To each their own I guess.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

Not all people are the same.
You can be fit and fat.
Fat also increases some risks like diabetes.

Everyone including ops friend should myob

There is not a single objective health measure that improves by carrying excessive body fat other than being dramatically underweight. That's reality.

Reality is that you and the rest of the fatphobes on this forum/in this culture don't give a rat's behind about a fat stranger's health. Fat bodies are an acceptable target for your concern trolling, othering, and ableism. That's it. You hide behind "health concerns" but if you really gave a damn about a stranger's health, you wouldn't lead by insulting their intelligence, framing yourself as superior because you wear a smaller size, and then treating them like a hapless idiot who needs your help or your opinion.

Being judged for existing in the body you've got isn't good for anyone's health, doesn't motivate people to change their body shape, and can actively harm people to the point of suicidal ideation and self-harm.

There's not a single objective health measure that improves by being judged by a stranger. THAT is reality, so STFU.

You might consider that when you quote a post, the prior discussion was included.

If you bothered reading, you would find I was responding to the notion that fitness and being fat can coexist. That’s just not true. In extremely rare cases people with an obese BMI may not be carrying around significant body fat far in excess of what’s healthy. That’s not the 99.9% of Americans in the obese category. That’s what I was responding to that caused you to get all butt hurt.

So no, there is not a single objective health measure that improves by carrying around excess body fat. Maybe go work on that instead of being butt hurt by people pointing out facts. Facts aren’t judgement - you just turn them into something about you because you don’t like general facts. Maybe also work on that while you are at it.

So you're an idiot, as well as an ass? Cool. Thanks for the information.

You are free to explain how there IS a single objective health measure that improves by carrying around excess body fat.

YES!!!! End of story!!

You are both free to explain how there is a single piece of data suggesting that shaming people helps facilitate behavior change.

We’ll wait.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

Not all people are the same.
You can be fit and fat.
Fat also increases some risks like diabetes.

Everyone including ops friend should myob

There is not a single objective health measure that improves by carrying excessive body fat other than being dramatically underweight. That's reality.

Reality is that you and the rest of the fatphobes on this forum/in this culture don't give a rat's behind about a fat stranger's health. Fat bodies are an acceptable target for your concern trolling, othering, and ableism. That's it. You hide behind "health concerns" but if you really gave a damn about a stranger's health, you wouldn't lead by insulting their intelligence, framing yourself as superior because you wear a smaller size, and then treating them like a hapless idiot who needs your help or your opinion.

Being judged for existing in the body you've got isn't good for anyone's health, doesn't motivate people to change their body shape, and can actively harm people to the point of suicidal ideation and self-harm.

There's not a single objective health measure that improves by being judged by a stranger. THAT is reality, so STFU.

You might consider that when you quote a post, the prior discussion was included.

If you bothered reading, you would find I was responding to the notion that fitness and being fat can coexist. That’s just not true. In extremely rare cases people with an obese BMI may not be carrying around significant body fat far in excess of what’s healthy. That’s not the 99.9% of Americans in the obese category. That’s what I was responding to that caused you to get all butt hurt.

So no, there is not a single objective health measure that improves by carrying around excess body fat. Maybe go work on that instead of being butt hurt by people pointing out facts. Facts aren’t judgement - you just turn them into something about you because you don’t like general facts. Maybe also work on that while you are at it.

So you're an idiot, as well as an ass? Cool. Thanks for the information.

You are free to explain how there IS a single objective health measure that improves by carrying around excess body fat.

YES!!!! End of story!!

The end of the story was back when you forgot to mind your own business, revealing your entire ass (however slender/flat).

[Anonymous]

Anonymous wrote:self-control. People like people that have self-control and self-regulation.

This. I am embarrased for anyone using these drugs for weightloss. How about you learn to exercise and not stuff your mouth full of processed garbage?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

This won't play out for many, many reasons...
1) we are not treating the root of the problem which is our sedentary lifestyle and our food supply
2) corporations and the people who get rich running them have a vested interest in keeping cheetohs and coke as part of our diet
3) human nature is to want this "quick fix" because we have evolved to conserve energy and consume as much energy as we can
4) we are more disconnected than ever because of social media and letting our "leaders" divide us in the interest of lining their own pockets
5) cars and Americans' obsession with big, plastic houses and big, dangerous cars
6) we still need to sell our soul to the company store just for health insurance
7) legalization and cultural acceptance of more and more recreational drugs

I lost 70 lbs on Ozmepic and completely changed what I ate and also exercised like crazy. It just allowed me to do those things without feeling completely deprived all the time. Stop spewing nonsense about quick fixes. Nothing quick or easy about it. I did the work but Ozempic helped greatly.

+1 Yes! Slow and steady!

I’m loosing about 1.3 lbs a week which is comparable to how it was when I was fanatically and obsessively focused on WW. Wegovy just helps balance everything out. It’s easier to make good food choices in rough situations and it makes day to day eating less fraught overall, which is nice. I’m actually enjoying my food because I know I won’t overeat. I eat and enjoy my portion and then I’m done!

I’ve had minimal side effects and as long as I keep my fiber up, there’s been no constipation. I don’t know if I’d call it a miracle, but it’s defined a game changer for me and my health.

[Anonymous]

A study just came out showing that Ozempic shrinks the heart muscle. That’s incredibly bad.

[Anonymous]

Anonymous wrote:

It's why people on these drugs are reporting that they also don't want to drink. It turns off a need. I have been taking one of the meds for almost a year. It gets rid of food obsession. That's as big a piece as is the appetite suppressant. I have OCD and I think this is probably related as well.

Can you expand on the OCD connection? Are you saying it stops OCD obsessive thoughts about food, or OCD obsessive thoughts in general? Has it decreased your anxiety?

PP. Yes, I think OCD may be connected to addiction--just my opinion and I'm not an expert. It stops obsessive thoughts about food which I now wonder if that I'd connected to OCD.

I do not think about food as often and I am incredibly calm about it. It sounds weird to say that I was anxious about food but I was. I thought about trying not to eat, what to eat, how much to eat, etc., pretty much all day. As a teen I veered into extreme dieting and occasional bulimia. I felt like I had overcome a lot of my issues before taking the med but really I had not. It has been a constant mental battle but in a way I don't think I even realized how much I thought about food until I wasn't doing it anymore.

I think it works on dopamine and many disorders like OCD, ADHD, depression, etc. involve
dopamine and serotonin. My family has OCD, addictions, ADHD, some diagnosed, some not. I think all these things are related. I'm just speculating but there have been other unexpected effects from these drugs and I don't think we understand addiction very well. As I said, I think this is about addiction which is different than needing to lose a few pounds via diet and exercise. Addiction medicine needs to be respected and studied or it's just all about 12 step programs. There is much more to learn.

Another thing I'll add us that it's taken me about a year to lose 30 pounds and I'm at my goal weight, though I couldn't get it for three months. Here's what the drug helped me do: sustain the progress for long enough to see results. I had a very hard time with that. It's hard to diet for a year. (I have also increased my exercise).