Friend who works in pharma went on a rant about how bad Ozempic etc is for people. ?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

Not all people are the same.
You can be fit and fat.
Fat also increases some risks like diabetes.

Everyone including ops friend should myob

There is not a single objective health measure that improves by carrying excessive body fat other than being dramatically underweight. That's reality.

Reality is that you and the rest of the fatphobes on this forum/in this culture don't give a rat's behind about a fat stranger's health. Fat bodies are an acceptable target for your concern trolling, othering, and ableism. That's it. You hide behind "health concerns" but if you really gave a damn about a stranger's health, you wouldn't lead by insulting their intelligence, framing yourself as superior because you wear a smaller size, and then treating them like a hapless idiot who needs your help or your opinion.

Being judged for existing in the body you've got isn't good for anyone's health, doesn't motivate people to change their body shape, and can actively harm people to the point of suicidal ideation and self-harm.

There's not a single objective health measure that improves by being judged by a stranger. THAT is reality, so STFU.

You might consider that when you quote a post, the prior discussion was included.

If you bothered reading, you would find I was responding to the notion that fitness and being fat can coexist. That’s just not true. In extremely rare cases people with an obese BMI may not be carrying around significant body fat far in excess of what’s healthy. That’s not the 99.9% of Americans in the obese category. That’s what I was responding to that caused you to get all butt hurt.

So no, there is not a single objective health measure that improves by carrying around excess body fat. Maybe go work on that instead of being butt hurt by people pointing out facts. Facts aren’t judgement - you just turn them into something about you because you don’t like general facts. Maybe also work on that while you are at it.

So you're an idiot, as well as an ass? Cool. Thanks for the information.

You are free to explain how there IS a single objective health measure that improves by carrying around excess body fat.

[Anonymous]

It's why people on these drugs are reporting that they also don't want to drink. It turns off a need. I have been taking one of the meds for almost a year. It gets rid of food obsession. That's as big a piece as is the appetite suppressant. I have OCD and I think this is probably related as well.

Can you expand on the OCD connection? Are you saying it stops OCD obsessive thoughts about food, or OCD obsessive thoughts in general? Has it decreased your anxiety?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

This won't play out for many, many reasons...
1) we are not treating the root of the problem which is our sedentary lifestyle and our food supply
2) corporations and the people who get rich running them have a vested interest in keeping cheetohs and coke as part of our diet
3) human nature is to want this "quick fix" because we have evolved to conserve energy and consume as much energy as we can
4) we are more disconnected than ever because of social media and letting our "leaders" divide us in the interest of lining their own pockets
5) cars and Americans' obsession with big, plastic houses and big, dangerous cars
6) we still need to sell our soul to the company store just for health insurance
7) legalization and cultural acceptance of more and more recreational drugs

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

This won't play out for many, many reasons...
1) we are not treating the root of the problem which is our sedentary lifestyle and our food supply
2) corporations and the people who get rich running them have a vested interest in keeping cheetohs and coke as part of our diet
3) human nature is to want this "quick fix" because we have evolved to conserve energy and consume as much energy as we can
4) we are more disconnected than ever because of social media and letting our "leaders" divide us in the interest of lining their own pockets
5) cars and Americans' obsession with big, plastic houses and big, dangerous cars
6) we still need to sell our soul to the company store just for health insurance
7) legalization and cultural acceptance of more and more recreational drugs

And I forgot the biggest one is that more children are obese than ever before and they pretty much physiologically CANNOT become normal weight adults if they come of age obese

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

Not all people are the same.
You can be fit and fat.
Fat also increases some risks like diabetes.

Everyone including ops friend should myob

There is not a single objective health measure that improves by carrying excessive body fat other than being dramatically underweight. That's reality.

Reality is that you and the rest of the fatphobes on this forum/in this culture don't give a rat's behind about a fat stranger's health. Fat bodies are an acceptable target for your concern trolling, othering, and ableism. That's it. You hide behind "health concerns" but if you really gave a damn about a stranger's health, you wouldn't lead by insulting their intelligence, framing yourself as superior because you wear a smaller size, and then treating them like a hapless idiot who needs your help or your opinion.

Being judged for existing in the body you've got isn't good for anyone's health, doesn't motivate people to change their body shape, and can actively harm people to the point of suicidal ideation and self-harm.

There's not a single objective health measure that improves by being judged by a stranger. THAT is reality, so STFU.

You might consider that when you quote a post, the prior discussion was included.

If you bothered reading, you would find I was responding to the notion that fitness and being fat can coexist. That’s just not true. In extremely rare cases people with an obese BMI may not be carrying around significant body fat far in excess of what’s healthy. That’s not the 99.9% of Americans in the obese category. That’s what I was responding to that caused you to get all butt hurt.

So no, there is not a single objective health measure that improves by carrying around excess body fat. Maybe go work on that instead of being butt hurt by people pointing out facts. Facts aren’t judgement - you just turn them into something about you because you don’t like general facts. Maybe also work on that while you are at it.

So you're an idiot, as well as an ass? Cool. Thanks for the information.

You are free to explain how there IS a single objective health measure that improves by carrying around excess body fat.

And you are free to scroll back up and re-read the bit about how concern trolling other people's health reveals nothing more than your own backside.

I don't have to justify my body to you. Nobody does. You need to learn to MYOB.

[Anonymous]

Anonymous wrote:No we didn’t. We just made more excuses. “Food noise” lol. You mean lack of discipline and a lifetime of yo yo dieting. Now you need to shove a pill in your face to not eat.

Another clown with no neuroscience knowledge. Please touch grass and heal.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I just worry that it’s new and long term issues with it cannot be known.

Nothing can ever be entirely known, but it's been used by diabetics for decades - it's not a new drug, it's newly approved for weight loss.

Meanwhile, the long term issues with being obese are well known.

Still, it’s scary to be putting a tween/young teen on a relatively new (it’s still not that well understood) drug indefinitely. And yet people are lining up to do this! It’s kind of crazy.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

Not all people are the same.
You can be fit and fat.
Fat also increases some risks like diabetes.

Everyone including ops friend should myob

There is not a single objective health measure that improves by carrying excessive body fat other than being dramatically underweight. That's reality.

Reality is that you and the rest of the fatphobes on this forum/in this culture don't give a rat's behind about a fat stranger's health. Fat bodies are an acceptable target for your concern trolling, othering, and ableism. That's it. You hide behind "health concerns" but if you really gave a damn about a stranger's health, you wouldn't lead by insulting their intelligence, framing yourself as superior because you wear a smaller size, and then treating them like a hapless idiot who needs your help or your opinion.

Being judged for existing in the body you've got isn't good for anyone's health, doesn't motivate people to change their body shape, and can actively harm people to the point of suicidal ideation and self-harm.

There's not a single objective health measure that improves by being judged by a stranger. THAT is reality, so STFU.

You might consider that when you quote a post, the prior discussion was included.

If you bothered reading, you would find I was responding to the notion that fitness and being fat can coexist. That’s just not true. In extremely rare cases people with an obese BMI may not be carrying around significant body fat far in excess of what’s healthy. That’s not the 99.9% of Americans in the obese category. That’s what I was responding to that caused you to get all butt hurt.

So no, there is not a single objective health measure that improves by carrying around excess body fat. Maybe go work on that instead of being butt hurt by people pointing out facts. Facts aren’t judgement - you just turn them into something about you because you don’t like general facts. Maybe also work on that while you are at it.

So you're an idiot, as well as an ass? Cool. Thanks for the information.

You are free to explain how there IS a single objective health measure that improves by carrying around excess body fat.

Not the person you are replying to and I have no dog in this fight and no strong opinion about ozempic.

But! Just to be difficult and since you posed this challenge - bone density tends to be better in patients who carry a bit of weight. And fractures - especially hip fractures - are no joke.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

This won't play out for many, many reasons...
1) we are not treating the root of the problem which is our sedentary lifestyle and our food supply
2) corporations and the people who get rich running them have a vested interest in keeping cheetohs and coke as part of our diet
3) human nature is to want this "quick fix" because we have evolved to conserve energy and consume as much energy as we can
4) we are more disconnected than ever because of social media and letting our "leaders" divide us in the interest of lining their own pockets
5) cars and Americans' obsession with big, plastic houses and big, dangerous cars
6) we still need to sell our soul to the company store just for health insurance
7) legalization and cultural acceptance of more and more recreational drugs

I can't fix any of that. If I wasn't on Wegovy, all of the above would still be true and also I'd be obese.
However, now that I'm on meds I move more (because I can), eat better and less, and drink zero alcohol. Those are wins for my health and if they bear out statistically they are wins for public health.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I was absolutely addicted to food and gained 150 pounds over my ideal healthy weight - severe morbid obesity on my 5’2” frame. I experienced joint pain, high BP, high cholesterol, and prediabetes. I ate and ate and ate and couldn’t ever stop thinking about my next meal and FOOD.

I did all the pre-op testing for bariatric surgery but balked at going forward with it because of the potentially fatal side effects and the research that informed me of the long term very high failure rate in terms of keeping the weight off, and the very high rate of transfer addictions to other substances and high risk behaviors.

I didn’t consider the weight loss drugs because gut health is a bit of an obsession for me after suffering years of post-cholecystectomy syndrome that led to a vitamin deficiency and much of the weight gain.

Over the last year I cured my food addiction and began steadily losing weight by ditching most sugar and ultra processed foods, cutting way back on animal products, and building my diet around high fiber nutrient dense foods that provide a variety of plants to my trillions of gut bacteria. I eat for my microbiome and to protect my liver.

I have never felt better in my adult life. Fiber is nature’s semaglutide - getting the RDA of fiber from a variety of whole natural foods mostly colorful vegetables and fruits and legumes, nuts seeds and whole grains naturally stimulates production of glp1 and regulates hunger and food cravings. Eating fiber is the only way to produce short chain fatty acids which are critical to improving and maintaining health.

It wasn’t easy at first. Food cravings for the food addicted are intense. I slipped back many times. I still let myself have a cheat day once a week but find I am less interested in those foods with each passing week. I pay close attention to have foods make me feel and I crave bad stuff less and less often because I love how my body sings on plant foods. My palate is more sensitive and I crave the taste of clean and healthy flavors and am overwhelmed by sugar and high fat foods. I hate how fried foods make me feel and almost never indulge in those anymore.

It’s harder, but it is definitely cheaper and healthier and the results will be greater and the side effects are limited to a short period of excessive flatulence until the gut stabilizes and begins to thrive on bean and veggies and fruits - the things we evolved to eat.

Down over 50 pounds, fully expect to reach goal weight on time - slow and steady loss while lifting weights and building fitness so skin issues are minimal. Skin and hair much improved - SCFAs transform health from inside out.

Also I am really proud of the journey I’ve been on.

Try it. A fiber fueled life is a great life.

Thank you for this. It’s inspiring. Truly.

No this is the lady who has been going around posting about her gas and “beautiful bms”. I recognize the writing style and the overly long post. I eat a similar diet of unprocessed foods but this lady just seems insufferable to me.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

PP you replied to. I say this very seriously. No drug is a miracle drug. Even penicillin, which saved millions of lives immediately when it put on the market before WWII.

Of course antibiotics have side effects but to act like penicillin was not a miracle drug, insanity. Cuts used to be potentially life threatening!

[Anonymous]

Anonymous wrote:self-control. People like people that have self-control and self-regulation.

But apparently can't write.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

This won't play out for many, many reasons...
1) we are not treating the root of the problem which is our sedentary lifestyle and our food supply
2) corporations and the people who get rich running them have a vested interest in keeping cheetohs and coke as part of our diet
3) human nature is to want this "quick fix" because we have evolved to conserve energy and consume as much energy as we can
4) we are more disconnected than ever because of social media and letting our "leaders" divide us in the interest of lining their own pockets
5) cars and Americans' obsession with big, plastic houses and big, dangerous cars
6) we still need to sell our soul to the company store just for health insurance
7) legalization and cultural acceptance of more and more recreational drugs

I lost 70 lbs on Ozmepic and completely changed what I ate and also exercised like crazy. It just allowed me to do those things without feeling completely deprived all the time. Stop spewing nonsense about quick fixes. Nothing quick or easy about it. I did the work but Ozempic helped greatly.

[Anonymous]

Ozempic is not without risks. Specifically, it dramatically slows digestion, which can cause dangerous constipation that can lead to necrosis. It should be used with caution for anyone with a compromised GI system. This has been slow-rolled by the pharma companies and kind of buried.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

The verdict is in. The lab rats have already been under scrutiny for many many years as this drug has already been in use. The fact that it is being used more widely now is really the only difference – most of the people going on it are already verging close enough to being Diabetic that the difference is almost negligible. Stop hating people because they’re fat and wish them luck on their journey.