Friend who works in pharma went on a rant about how bad Ozempic etc is for people. ?

[Anonymous]

I think we still don't know the true rates yet for GLP1s potentially causing suicides and blindness.

How much risk are you willing to take for losing weight if a potential side effect is losing your eyesight? 1/100? 1/1000? 1/1,000,000? Many people wouldn't want to risk their eyesight at all. We will see.

[Anonymous]

Anonymous wrote:I didn’t have the nerve to tell her my dh is on it, as is my sibling, and both look and feel great.

Why do people who’ve never been on it trash these drugs? Interestingly this friend needs to lose weight related to a very serious health condition that is affected by weight. The issue seemed very sensitive so I didn’t want to argue, but I don’t understand the rigidity.

My sister is on one of these drugs. She was obese and is now very skinny. Got face lift and neck lift. Loose skin on body tightened up. Hair extensions. The works. She looks amazing. But can’t stop taking it even though she’s lost way too much muscle. She drinks protein shakes and can barely choke down food. But wants to be skinny. It’s her new obsession. Used to be food and now it’s this.

I find this very alarming and I’ve told her so. She just gets angry and says I just can’t understand. She has no disease. She was a gymnast that became an emotional eater; she needed therapy, not a drug. She’s still emotionally unhealthy. All of this is unnerving.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

NP

What’s truly short sighted is to use drugs to fix the *symptom* rather than address the underlying problem.

(i.e. why are 75 percent of Americans overweight in the first place?)

I don’t think any of us would disagree with that. But it will take a generation or more to accomplish. I’m living now and need a solution now. Having lost and regained 30-50 pounds 5 different times during my life, this medicine is giving me hope that I can hit a normal weight and cut back to a small maintenance dose and be healthy for the long term.

These drugs are essentially appetite suppressants? Is that right?

It’s not that. It does something to the inflammatory response and one side effect is appetite suppression, but it’s more than that. My close friend who went on it had her lifelong severe rosacea clear up within a month of starting, before any serious weight was lost. Her dermatologist told her that she’s seeing the same thing with other patients.

I don’t know what is going on but weight is just one piece of the puzzle here.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

What could fatness be a side effect of?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

What could fatness be a side effect of?

Many things. For me it was a thyroid issue. The weight issue resolved easily when medicated for hypothyroidism.

[Anonymous]

[twitter]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

What could fatness be a side effect of?

Gluttony? Laziness?

[Anonymous]

Anonymous wrote:I think we still don't know the true rates yet for GLP1s potentially causing suicides and blindness.

How much risk are you willing to take for losing weight if a potential side effect is losing your eyesight? 1/100? 1/1000? 1/1,000,000? Many people wouldn't want to risk their eyesight at all. We will see.

Glp-1s are a natural hormone that regulates hunger and is created in the small intestine when consuming a proper, high fiber diet. Glp-1s don’t cause blindness or any other serious health issues.

Glp-1 receptor agonists are the diet drugs like Ozempic which mimic the natural hormone that regulates hunger.

Eating a high FIBER nutrient dense diet naturally increases production of Glp-1s.

That’s the thing peeps. You CAN get the same results and be much healthier overall if you change the way you eat - not by taking a drug that makes food stay in your gut for many hours if not days, that can cause deadly blockages or blindness or whatever other adverse side effects that no matter how rare are not as rare as the zero side effects of eating a healthy high fiber diet. Oh sorry, you might fart a bit at the start while your gut biome rebalances.

Taking Ozempic et al. doesn’t produce short chain fatty acids which are critical to maintaining optimal health.

Yes it’s hard to kick addiction to sugar and additives after years of eating crap, but it can be done and the results will last longer promote better health and not require you to mess with your gut for the rest of your life by taking a very expensive drug. Just eat beans, fruits, veggies, whole grains nuts and seeds. Repeat every day. Live long and prosper.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

What could fatness be a side effect of?

Inflammation, or addiction.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

What could fatness be a side effect of?

Addiction. Food addiction.

[Anonymous]

Anonymous wrote:I agree with your friend, OP. What does him being fat have to do with anything? He's not allowed to have an opinion about anything because he's fat? Also, what illness are completely dependent upon weight? Because I know of people with type 2 diabetes, HTN, hypercholesterolemia, etc who are thin. Just FYI, it's not always about the weight (unless it's in extreme cases). Often times, it's genetics and environment. Obviously, lifestyle factors in but that doesn't always guarantee significant weight loss. People can still be fat and see significant changes in biochemical markers with exercise and realistic diet changes. Sure, if they want to lose weight to breathe better or get around better, that's fair. But in order to do that they have to practice breathing and getting around while fat first. We live in a world where it's still acceptable to abuse fat people out in the open and think it's okay. That's what's happening in this thread. Fat people can have opinions. I wish people on these meds all the best.

You struggle with logic, I can see.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I didn’t have the nerve to tell her my dh is on it, as is my sibling, and both look and feel great.

Why do people who’ve never been on it trash these drugs? Interestingly this friend needs to lose weight related to a very serious health condition that is affected by weight. The issue seemed very sensitive so I didn’t want to argue, but I don’t understand the rigidity.

My sister is on one of these drugs. She was obese and is now very skinny. Got face lift and neck lift. Loose skin on body tightened up. Hair extensions. The works. She looks amazing. But can’t stop taking it even though she’s lost way too much muscle. She drinks protein shakes and can barely choke down food. But wants to be skinny. It’s her new obsession. Used to be food and now it’s this.

I find this very alarming and I’ve told her so. She just gets angry and says I just can’t understand. She has no disease. She was a gymnast that became an emotional eater; she needed therapy, not a drug. She’s still emotionally unhealthy. All of this is unnerving.

Your sister is an edge example. Just like saying no one should try to be a healthy weight because some people lose too much and become anorexic

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Your friend is probably very insecure about his own weight, and also anxious about trying this drug himself because he's in a position to read about the clinical trial dossiers and post-commercialization reports on severe side effects.

I have to say, as a biologist working in pharma, he's not wrong: some people have died due to complications from slow-moving bowels, and a lot of people taking this drug will realize they can't stop taking it, otherwise the weight will come back. If I had weight issues, I would hesitate to try it too, because I've read some research articles about it that are quite disturbing!

Let's just say it's not the miracle drug people think it is. I hope your husband and sibling are very educated about it and know the limitations of their medication.

I totally disagree. I think it is a miracle drug. 75 percent of Americans are overweight. This drug helps tremendously, with relatively manageable side effects. To ignore that is so short sighted.

But people will argue vehemently that you can be fit and fat. Why are we suddenly rushing to use drugs to control weight if it doesn’t matter? Also, let’s see how these lab rats fare in a few years after continued use.

You do know it has been studied in lab rats for years, right? It was used for diabetes control

Cool. Let’s still check back in a few years and see how everyone is doing.

We’ll come back in a few years and see obesity is way down, along with cancers, heart disease, alcohol and drug abuse. Once fully understood these drugs will have big impacts and be widely used.

Maybe but again people have been arguing for years that fat isn’t really a problem. I guess that was a big lie.

It is possible that fat is a side effect of something else that is a big issue. We are so ignorant about what is going on here.

What could fatness be a side effect of?

Many things. For me it was a thyroid issue. The weight issue resolved easily when medicated for hypothyroidism.

But a lot of people aren’t that lucky and never lose the weight