Semaglutide FOMO

[Anonymous]

Anonymous wrote:

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

Mid-50s and work out 3-5 days a week (cardio and weights). Lost 54 pounds over an entire year, and kept working out. No bad side effects (only side effect is I had to buy all new clothes as everything was hanging off me), no muscle loss.

Yup, I just had to order some size 8 pants for work since the 10's I ordered in the summer (to replace the 12's I had) were baggy. I haven't been a size 8 for decades so am pretty excited about it. People on DCUM may consider size 8 obese but I have moved my BMI from the 28's to the 22's so well within normal range.

[Anonymous]

Anonymous wrote:

Anonymous wrote:My BMI is 34, and I am wanting it. I have a new concierge doc and we have our first appt in January and will talk about it then.

It's hard to get your hands on now, though, isn't it?

Yes. I have been on it for almost a year (though I didn’t lose as much as I had hoped). I haven’t been able to get it for two months, during which time I have regained most of the weight I had lost.

I was on it for 11 months and only lost 15 lbs, so I have FOMO of the people who have lost 30+. I haven’t been able to get it for 2 months either but have only gained back 3lbs. I’ve been working out like a fiend and trying to maintain the non-drinking I did while on it.

[Anonymous]

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

I'm on Wegovy. My weight loss has been steady and modest. 1-2 lbs per week. I was and am active so I have not lost any muscle. I don't know if it would be different with a rapid weight loss, but I'm super happy with my slower steady loss.

[Anonymous]

Anonymous wrote:

Anonymous wrote:My BMI is 34, and I am wanting it. I have a new concierge doc and we have our first appt in January and will talk about it then.

It's hard to get your hands on now, though, isn't it?

Yes. I have been on it for almost a year (though I didn’t lose as much as I had hoped). I haven’t been able to get it for two months, during which time I have regained most of the weight I had lost.

This is why I had no desire to try it. It's lifelong, which I would be ok with if I had diabetes, but not ok with otherwise. And I'm a good 50 pounds overweight.

Doing it the long slow way, and I've found the only way I can lose is to eliminate all sugar except fruit.

[Anonymous]

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

It’s fear mongering. All weight loss comes with varying amounts of muscle loss. You can’t lose just fat and no lean mass with a calorie deficit. You can preserve as much lean mass as possible with strength training and proper macronutrients.

If you restricted your calories enough to lose 1-3 pounds a week without Ozempic you’d lose just as much muscle.

[Anonymous]

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

I had Ozempic FOMO too. That prune look from the muscle loss and the dramatic thinning hair make it a no for me.

[Anonymous]

Anonymous wrote:

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

It’s fear mongering. All weight loss comes with varying amounts of muscle loss. You can’t lose just fat and no lean mass with a calorie deficit. You can preserve as much lean mass as possible with strength training and proper macronutrients.

If you restricted your calories enough to lose 1-3 pounds a week without Ozempic you’d lose just as much muscle.

It’s all about the degree of muscle loss, PP. Studies are showing significantly more muscle loss with GLP1s than other methods.

That’s why people gain so much weight once they stop taking these meds.

[Anonymous]

[code]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

It’s fear mongering. All weight loss comes with varying amounts of muscle loss. You can’t lose just fat and no lean mass with a calorie deficit. You can preserve as much lean mass as possible with strength training and proper macronutrients.

If you restricted your calories enough to lose 1-3 pounds a week without Ozempic you’d lose just as much muscle.

It’s all about the degree of muscle loss, PP. Studies are showing significantly more muscle loss with GLP1s than other methods.

That’s why people gain so much weight once they stop taking these meds.

This is silly. I’ve lost 50lbs. It’s not muscle loss, it’s eating a lot less.


That said, OP, it’s still great but I definitely reached a place where it doesn’t control my appetite nearly as much, and I don’t have side effects nearly as much. What is that? Is it tolerance? Or metabolism? I think it’s metabolism, personally. I’ve always felt like the idea of “set points” rang true. So I just think they have a lot more to learn about who loses how much and why.

It’s a miracle drug though for me. My diabetes and obesity are in remission or whatever. I don’t know. My numbers look phenomenal and I feel amazing.

[Anonymous]

Anonymous wrote:

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

I'm on Wegovy. My weight loss has been steady and modest. 1-2 lbs per week. I was and am active so I have not lost any muscle. I don't know if it would be different with a rapid weight loss, but I'm super happy with my slower steady loss.

I think this is key. I lost a lot the first 3 months (25 lbs in 3 months) but it’s slowed down since then and I’ve rebuilt any muscles I lost. I’ve lost 11 lbs in the last 6 months. Still have a few more lbs to go but am tapering off ozempic now to see how that goes.

[Anonymous]

I’m on the .5 dose and have two more weeks of it left. I’m worried about where to get it refilled. I feel like I got lucky before.

[Anonymous]

My insurance company just stopped covering it in January. Out of pocket is $1500 a month. $900 with a manufacturer’s coupon so I guess I won’t be on it anymore. Oh well.

[Anonymous]

Anonymous wrote:[code]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:For those of you in Ozempic etc, how are you dealing with the muscle loss. I keep reading that the weight loss experienced by most people on these drugs includes much more muscle loss than other methods (with the exception of bariatric surgery). I don’t want to lose muscle and end up “skinny fat”.

It’s fear mongering. All weight loss comes with varying amounts of muscle loss. You can’t lose just fat and no lean mass with a calorie deficit. You can preserve as much lean mass as possible with strength training and proper macronutrients.

If you restricted your calories enough to lose 1-3 pounds a week without Ozempic you’d lose just as much muscle.

It’s all about the degree of muscle loss, PP. Studies are showing significantly more muscle loss with GLP1s than other methods.

That’s why people gain so much weight once they stop taking these meds.

This is silly. I’ve lost 50lbs. It’s not muscle loss, it’s eating a lot less.


That said, OP, it’s still great but I definitely reached a place where it doesn’t control my appetite nearly as much, and I don’t have side effects nearly as much. What is that? Is it tolerance? Or metabolism? I think it’s metabolism, personally. I’ve always felt like the idea of “set points” rang true. So I just think they have a lot more to learn about who loses how much and why.

It’s a miracle drug though for me. My diabetes and obesity are in remission or whatever. I don’t know. My numbers look phenomenal and I feel amazing.

Your response makes no sense, PP. Are you denying that more muscle is lost with GLP1s than with other weight loss modalities?

[Anonymous]

Anonymous wrote:My insurance company just stopped covering it in January. Out of pocket is $1500 a month. $900 with a manufacturer’s coupon so I guess I won’t be on it anymore. Oh well.

Bum

[Anonymous]

Anonymous wrote:

Anonymous wrote:My insurance company just stopped covering it in January. Out of pocket is $1500 a month. $900 with a manufacturer’s coupon so I guess I won’t be on it anymore. Oh well.

Bum

I suspect the pendulum will go one of two ways (1) more insurance companies will stop covering and will require pre-authorization for those already on it, which presumably many won’t get unless they are still obese or (2) it will become more readily available and cheaper for everyone. For those currently on it, I wouldn’t get too used to it. Zero chance insurance companies are going to just cover people at this cost forever. They will wise up and you will likely get kicked off once your weight reaches normal bringing everyone back to where they started.

[Anonymous]

The compounded stuff works great and is inexpensive. No need to pay $900.