Anyone changing behavior due to the latest uptick in Covid?
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Anonymous
Note the phrase “without *documented* prior SARS-CoV-2 infection.” Given the large percentage of asymptomatic cases, and the even larger number of symptomatic cases so mild no one would have thought to test, many people had undocumented cases. It’s entirely plausible that Omicron is inherently less virulent, too, but no doubt immunity played a large role in less severe outcomes. |
Anonymous
As my family has several people who take immunosuppressants, I’ll admit I was a bit worried until I heard some anecdotal information on outcomes from local transplant surgeons. By late May, though, it was definitely clear the actual risk, even to us, was grossly overblown. And the quasi-lockdown never made any sense. Several of my coworkers thought I was nuts for packing up nearly my whole office as it began. I wasn’t particularly worried about covid, even then, but I said the two weeks to “flatten the curve” was nonsense, and there was no realistic path back without simply a change in mindset. |
Anonymous
| I’m shocked that the school systems are not considering virtual options for at least the beginning of school. It’s going to be brutal and then it’s going to spread rapidly. I wish I could keep them home |
Anonymous
They address this in the study and conclude that immunity from prior infections was not the reason for Omicron's milder effects relative to Delta. They point to the fact that participants with a documented prior infection had a much less severe case if they subsequently contracted Omicron rather than Delta. From the article: https://www.medrxiv.org/content/10.1101/2022.01.11.22269045v1.full.pdf "Although ascertainment of SARS-CoV-2 infection history is imperfect because many infections may have gone untested or may not have been documented in a patient’s EHR, prior infection among individuals with a history of a positive SARS-CoV-2 test result should be accurately coded and false positive PCR tests are rare. Thus, the finding of a reduction in severity of Omicron in patients with known prior infection is compelling evidence of an intrinsically less severe infection, rather than only different (more immune) persons becoming infected with the Omicron variant." |
Anonymous
PP again. Studies with mice and hamsters (with no immunity) yield similar results, indicating Omicron is milder than earlier strains. https://pubmed.ncbi.nlm.nih.gov/35062015/ "we observed less infection by B.1.1.529 [Omicron] in ... mice than by previous SARS-CoV-2 variants, with limited weight loss and lower viral burden in the upper and lower respiratory tracts. In ... hamsters, lung infection, clinical disease and pathology with B.1.1.529 were also milder than with historical isolates or other SARS-CoV-2 variants of concern. Overall, experiments from the SAVE/NIAID network with several B.1.1.529 isolates demonstrate attenuated lung disease in rodents, which parallels preliminary human clinical data. |
Anonymous
I honestly can’t tell if this post is serious… Can someone help my sarcastic detector? |
Anonymous
is this a parody? |
Anonymous
It’s not going to be brutal. |
Anonymous
If I’m reading the data from the study correctly, that’s a ridiculously improper argument to make based on the data. Look at Table S4, in the Prior Infection Status row. That claim appears to be based on 1 out of 43 non-Omicron patients having symptomatic hospitalization, versus 1 out of 508 Omicron patients (in both cases having a prior documented infection). You obviously can't draw any conclusions from that. There's just not enough data. Any suggestion otherwise is completely irresponsible. Am I misinterpreting that? |
Anonymous
I think so. Or a troll. |
Anonymous
Lucky you, not knowing anyone who died in 2020, when people with pre-existing conditions, and not a few young adults with no pre-existing conditions, were dying because the viral load of the initial, virulent strain overwhelmed their systems. But you probably also think that those deaths didn't happen at all. Conspiracy theory, right, PP? You can debate about the current variants and how bad they are or aren't, but your attitude indicates you don't give a s**t about potentially infecting others even back when the virus was clearly killing people, and too little was known yet to do much about it at that time. |
Anonymous
+1 I don't know about "back with a vengeance," but yes, coming back, because people like that PP are all about themselves. They have zero concept of public health and zero concern for people they don't know, who are more vulnerable than they themselves are. They prefer to fantasize that anyone still concerned or taking any measures is paranoid and living locked in a basement because that makes them feel superior and vindicated. Their self-centeredness is sad. |
Anonymous
Not paranoid. Just out-of-touch. Covid is here to stay, and, basically, since the introduction of the vaccine, it’s as good as it's going to get. |
Anonymous
We need the government to ban travel, or at least shutdown the airlines. |
Anonymous
And bars! Unless they also have live music, then it's fine. As Marc Elrich always knew, the covid virus hates live music. |