For young men, the risk of myocarditis from the Moderna vaccine specifically is higher than the risk of myocarditis from covid itself. Not true for young women, older men, older women, or any vaccine other than Moderna. |
Science and facts for you: https://pubmed.ncbi.nlm.nih.gov/35993236/ "In men younger than 40 years old, the number of excess myocarditis events per million people was higher after a second dose of mRNA-1273 than after a positive SARS-CoV-2 test (97 [95% CI, 91-99] versus 16 [95% CI, 12-18]). " |
DP Yes, agree with your earlier points. And from Pfizer's own product disclosures: "Authorized or approved mRNA COVID-19 vaccines show increased risks of myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining outside the heart), particularly within the first week following vaccination. For COMIRNATY, the observed risk is highest in males 12 through 17 years of age. Seek medical attention right away if you have any of the following symptoms after receiving the vaccine, particularly during the 2 weeks after receiving a dose of the vaccine: chest pain, shortness of breath, feelings of having a fast-beating, fluttering, or pounding heart. Additional symptoms, particularly in children, may include: Fainting, Unusual and persistent fatigue or lack of energy, Persistent vomiting, Persistent pain in the abdomen, Unusual and persistent cool, pale skin " https://www.pfizer.com/news/press-release/press-release-detail/pfizer-amends-us-government-paxlovid-supply-agreement-and |
Yeah, no. |
right, that’s acute myocarditis. we don’t know if there could be longer term or cumulative heart risks for other populations if they get an annual mRNA vax. |
Duh. I was being sarcastic. See the eye roll? |
DP Agree that young men face an elevated risk. The picture is even starker for all ages if you look at actual hospitalization data. In the Nordic nations and the UK, there have been 3x to 5x as many hospital admissions for covid vaccine-related myocarditis for all ages as from covid-related myocardititis; 10x for young males in Nordic nations. |
Yes, this exactly. There have been a few studies in Thailand and Switzerland where they actively monitored recipients of mRNA vaccines before/after receipt. The Swiss study found that 1 in 35 persons had mild myocardial injury from one mRNA vaccine as evidenced by high troponin levels post-vaccination. The injuries were transient and no case rose to the full level of a myocarditis diagnosis, although two participants with chest pain were deemed to have probable myocarditis. https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejhf.2978 However, as you note, we have no idea what risks these mild cardiac injuries might pose, particularly if combined with subsequent stressors like future covid/other illnesses and/or additional covid vaccines. |
+1. I have friends and family in the UK, Germany, Norway, and Japan. Annual boosters are recommended only for at-risk populations in ALL of those countries. The US recommendation really is the outlier and I have a hard time believing that all of those countries are wrong and we're right. Most likely, the actual science doesn't show a clear benefit, but also no clear risks, so countries with a more robust public health system can be more nuanced than in the US. This is from Germany and is the most logical and concise explanation of the advice I've seen. I've had three rounds of COVID vaccines and it's been in our house three times (only once did the kids and I test positive during the initial Omicron wave). We all get our flu shots and I'm sure we have plenty of immune-boosting environmental exposure to COVID, but until there's clear enough evidence that makes everywhere else change their guidelines, I don't feel the need to put my needle-phobic kids and myself through more boosters. Basic knowledge Who is recommended a vaccination? Since the beginning of the COVID-19 pandemic, infection trends have changed greatly. At this point in time, it can be assumed that SARS-CoV-2 is transitioning to an endemic wave-like event. This means that while the virus will continue to circulate within the population, the milder disease progressions of Omicron virus variants and the high immunity within the population on account of vaccination and past infection have resulted in there now being significantly fewer instances of severe illness. In contrast with earlier virus variants, infections with the Omicron variant also appear to result in fewer cases of long COVID. Furthermore, various studies indicate that full vaccination may provide a certain level of protection against long COVID (Useful information for patients and interested parties). The Standing Committee on Vaccination (STIKO) has entered its COVID-19 vaccination recommendations in the immunisation schedule for recommended standard vaccinations. Healthy people aged between 18 and 59 years (including pregnant people) are recommended a basic immunisation as well as a booster to build up a basic immunity. It is important that the immune system is exposed to pathogen components (through vaccination) or the pathogen itself (through infection) three times. At least two such exposures should occur through vaccination. Groups of people who are at increased risk are recommended an additional booster vaccination once a year. The vaccination should be administered with a variant-adapted vaccine and generally at least 12 months after the previous vaccination or infection. Preferably vaccinations should be administered in autumn, so that in case of growing infection rates, vulnerable people still have the best-possible protection in autumn and winter. This applies to: All people aged 60 or over Residents of long-term care facilities Anyone over the age of 6 months with an underlying condition People of all ages with an increased infection risk on account of their occupation in medical or long-term care Family members and close contacts of people for whom the COVID-19 vaccination is unlikely to produce a protective immune response For people with an immune deficiency and a relevant limited immune response, additional vaccine doses in shorter intervals may be beneficial. Whether additional vaccine doses are needed is determined by the attending physician. https://www.bundesgesundheitsministerium.de/en/coronavirus/faq-covid-19-vaccination |
Well, whatever you call it, this is the analysis of the effects of the latest shot. The reason that the benefits are a tiny fraction of the benefits of the first shot because people have existing immunity, from prior exposure and/or prior vaccines. |
+1. The US just pushes it on everyone, of all ages, to "simpilfy" the message. And well, to make sure the billions of taxpayer dollars spent on this new vaccine doesn't go to waste (spoiler alert: it will). |
DP. You're certainly right that the myocarditis risk is higher from covid itself than from the vaccine, but that doesn't really demonstrate value given that the vaccine doesn't prevent covid. Honest question: is there reasonably good data showing that the myocarditis risk from covid is lower after being vaccinated? And, given that nearly all of us have had covid already, is the myocarditis risk from infection lower after being vaccinated versus having a prior infection? |
This might be the only post I've seen that I completely agree with. |
I just heard that COVID is the 4th leading cause of death in the U.S. |
When the CDC references post-vaccine myocarditis, they often note that cases are generally mild and resolve fully. However, it is interesting to look at one follow-up study of 16 youths with resolved acute post-vaccine myocarditis. Despite the resolution of their acute cases, eleven participants still had a small amount of heart scarring at their 3-8 month follow-up. https://pubmed.ncbi.nlm.nih.gov/35351530/ While the amount of scarring was small and the youths' cardiac function was normal, any amount of heart scarring in youth is undesirable as it could become a substrate for arrhythmia down the road that could be triggered by exercise. Continued follow-up study will be needed to see what the long-term effects (if any) are. |