Success after 6 or more embryo transfers?

[Anonymous]

Has anyone had a healthy baby with the 6th or more embryo transfer after not having success with the first 5? Would love a little ray of hope.

[Anonymous]

Sorry, I know how tough it is. I had success after 2 tries but I also did PGD so my embryos were tested. Did you do PGD to make sure that embryos were "normal." I do know of someone who had success on her 5th try when she finally tested embryos and only implanted healthy embryos. She now has two little ones. Second I would ask if you have confidence in your IVF doctor. I did the first rounds in DC and then went to Boston IVF. I know there are several good docs in DC area though too. Best of luck!

[Anonymous]

Anonymous wrote:Sorry, I know how tough it is. I had success after 2 tries but I also did PGD so my embryos were tested. Did you do PGD to make sure that embryos were "normal." I do know of someone who had success on her 5th try when she finally tested embryos and only implanted healthy embryos. She now has two little ones. Second I would ask if you have confidence in your IVF doctor. I did the first rounds in DC and then went to Boston IVF. I know there are several good docs in DC area though too. Best of luck!

This is good advice and it's awesome that you only needed 2 tries. We have only had 0-2 blastocysts per round for rounds 1-4 so we just went ahead with the transfer since we had nothing to lose. But with our 5th round we had 8 day 5 blastocysts. We transferred 3 and froze 5. I was so sure this was the round that would work that I didn't even think to get the remaining ones tested, but now I wish I had. Lesson learned! I never thought I'd be in this position but I really think it will work eventually. - OP

[Anonymous]

I know someone, and that child has a very very rare genetic condition.

[Anonymous]

Me! Transferred a total of 8 untested embryos with only negative cycles and miscarriages. Switched clinics and the first retrieval produced 6 PGS normal embryos. The first embryo transferred is nursing in my arms as I type this.

[Anonymous]

Anonymous wrote:Me! Transferred a total of 8 untested embryos with only negative cycles and miscarriages. Switched clinics and the first retrieval produced 6 PGS normal embryos. The first embryo transferred is nursing in my arms as I type this.

Smart move and congrats! Do you mind sharing which clinic/doctor you left and which clinic/doctor you switched to?

[Anonymous]

I know 2 women who were successful after 5 cycles. I think cycle 6 and 8 respectively. One had a single (but transfered I think 5 embryos that cycle) the other twins. All three kids have autism.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Sorry, I know how tough it is. I had success after 2 tries but I also did PGD so my embryos were tested. Did you do PGD to make sure that embryos were "normal." I do know of someone who had success on her 5th try when she finally tested embryos and only implanted healthy embryos. She now has two little ones. Second I would ask if you have confidence in your IVF doctor. I did the first rounds in DC and then went to Boston IVF. I know there are several good docs in DC area though too. Best of luck!

This is good advice and it's awesome that you only needed 2 tries. We have only had 0-2 blastocysts per round for rounds 1-4 so we just went ahead with the transfer since we had nothing to lose. But with our 5th round we had 8 day 5 blastocysts. We transferred 3 and froze 5. I was so sure this was the round that would work that I didn't even think to get the remaining ones tested, but now I wish I had. Lesson learned! I never thought I'd be in this position but I really think it will work eventually. - OP

You can defrost and test. The research shows that it doesn’t really affect your chances of success if the blast survives the initial thaw. After 5 BFNs, I would really try to narrow down the variables at play before transferring more. I’d also look into ERA testing and testing for NK cells to see if there is something in the uterine environment that is causing the issues.

[Anonymous]

My advice is to stop before you run out of funds. Give yourself the option of donor eggs/sperm/embryo or traditional adoption.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Sorry, I know how tough it is. I had success after 2 tries but I also did PGD so my embryos were tested. Did you do PGD to make sure that embryos were "normal." I do know of someone who had success on her 5th try when she finally tested embryos and only implanted healthy embryos. She now has two little ones. Second I would ask if you have confidence in your IVF doctor. I did the first rounds in DC and then went to Boston IVF. I know there are several good docs in DC area though too. Best of luck!

This is good advice and it's awesome that you only needed 2 tries. We have only had 0-2 blastocysts per round for rounds 1-4 so we just went ahead with the transfer since we had nothing to lose. But with our 5th round we had 8 day 5 blastocysts. We transferred 3 and froze 5. I was so sure this was the round that would work that I didn't even think to get the remaining ones tested, but now I wish I had. Lesson learned! I never thought I'd be in this position but I really think it will work eventually. - OP

You can defrost and test. The research shows that it doesn’t really affect your chances of success if the blast survives the initial thaw. After 5 BFNs, I would really try to narrow down the variables at play before transferring more. I’d also look into ERA testing and testing for NK cells to see if there is something in the uterine environment that is causing the issues.

I really appreciate this and I wish I had been more aware of importance of testing given my history and age (just turned 41). The thought of having a baby with a genetic abnormality is a lot to handle, especially if it's preventable. DH and I are frantically researching thaw/test/refreeze now so thanks again.

[Anonymous]

Anonymous wrote:My advice is to stop before you run out of funds. Give yourself the option of donor eggs/sperm/embryo or traditional adoption.

Thanks. I'm not quite ready to give up yet. I'm in a rare situation where my insurance covers most of the cost, which is the only reason I could do the 5 that we've already done.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Me! Transferred a total of 8 untested embryos with only negative cycles and miscarriages. Switched clinics and the first retrieval produced 6 PGS normal embryos. The first embryo transferred is nursing in my arms as I type this.

Smart move and congrats! Do you mind sharing which clinic/doctor you left and which clinic/doctor you switched to?

Sure, and thanks! I saw Dr. M at CCRM NOVA.

[Anonymous]

Anonymous wrote:

Anonymous wrote:My advice is to stop before you run out of funds. Give yourself the option of donor eggs/sperm/embryo or traditional adoption.

Thanks. I'm not quite ready to give up yet. I'm in a rare situation where my insurance covers most of the cost, which is the only reason I could do the 5 that we've already done.

I’m the poster you are responding to. We did the thaw and test on our last blast. What we were told is that the risk is really in the thawing process and if the blasts were frozen with recent technology, the risk of damage is low. Essentially, if the blast does not thaw successfully, it would not have been suitable for transfer anyway. Good luck!

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:My advice is to stop before you run out of funds. Give yourself the option of donor eggs/sperm/embryo or traditional adoption.

Thanks. I'm not quite ready to give up yet. I'm in a rare situation where my insurance covers most of the cost, which is the only reason I could do the 5 that we've already done.

I’m the poster you are responding to. We did the thaw and test on our last blast. What we were told is that the risk is really in the thawing process and if the blasts were frozen with recent technology, the risk of damage is low. Essentially, if the blast does not thaw successfully, it would not have been suitable for transfer anyway. Good luck!

Sorry, I meant I’m the 16:22 poster.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Me! Transferred a total of 8 untested embryos with only negative cycles and miscarriages. Switched clinics and the first retrieval produced 6 PGS normal embryos. The first embryo transferred is nursing in my arms as I type this.

Smart move and congrats! Do you mind sharing which clinic/doctor you left and which clinic/doctor you switched to?

Sure, and thanks! I saw Dr. M at CCRM NOVA.

What protocols did you try and what protocol were you on when you got your 6 normals?