Actually, any weight loss causes you to lose a lot of muscle if you aren't making a point of doing heavy lifting. It doesn't matter whether the weight loss is through a GLP, dieting, or cardio. If you aren't lifting and eating enough protein, you'll lose a lot of both fat and muscle. |
Regarding cost, it will be so much cheaper in a couple of years when the patents expire. |
Totally false. If the drug targeted muscle no one would take it. When you lose weight you lose some muscle! And so many people on the drugs are working out more than they ever did. |
| I have been on GLP-1s for about 1.5 years and have lost around 20 pounds. The lighter doses of semaglutide did not do much for me, I had some reflux/sulphur burbs - but no other effects and I ate normally. I dropped 10 pounds on the higher dose of semaglutide over a few months. Then I could not get the higher does of semaglutide and switched to tirzepatide. That seems to have worked a little better for me - I have lost another ten pounds in the past four months. I am 50 and was fairly sedentary for the last 10 years with young kids. I am now post-menapausal and have a family history of obesity. When I travel I don't take the shots - so I have had a few weeks of the year off-meds, which probably contributes to lower success, but only somewhat I think. I have returned to doing Pilates and yoga several times a week since January, and am feeling more comfortable in my body - which I attribute to the weight loss and all of my clothes fitting (during Covid I stopped wearing "hard pants" and am back into my pre-kids jeans). That said, I will probably always be a size 12 - because I am just not seeing big weight loss and the drugs do not effect me the way they do other people (honestly, I am like this with a lot of drugs, pregnancy - my body just tolerates change). My diet is fairly healthy and I am eating less since taking GLPs because of the reflux. |
Mid-50s here. I’ve been on Zepbound for about 7 months and went from 230 to 195, mostly on the 7.5 dose. BMI dropped from 32.5 to 27, and body fat from 34% to 24%. Recently I’ve been spacing doses out to about every 10 days without any noticeable increase in hunger. Other changes: I now lift heavy 4–5x per week and take creatine daily (both new). My body scans show no muscle loss so far. I don’t track calories anymore but consistently get 8,000+ steps/day. Still drink vodka seltzers most nights. One unexpected benefit: a driving-related anxiety (bridges/highway trucks) that started during COVID has resolved. GI-wise, things are much more normal/consistent now compared to pre-Zepbound. I do have to stay on top of hydration and fiber (Metamucil). |
| I have lost 50lbs and get an InBody scan monthly to track trends. The one month that I wasn't lifting as much as I had been in previous months (due to travel, mostly) was the only month that I lost muscle mass. If people are exercising/lifting weights/eating enough protein, they shouldn't lose much muscle mass. |
NP. The cost has gone way down. I've been on a GLP for 16 months now and it's been totally life changing. After years of binging and starving and hating my body, I am now my dream weight without any effort, any feeling deprived, no starving. I just take 1 mg/week which costs me $299 for 60 weeks! That's right - a 60mg vial is $299. That is 50 cents per week. There is no need to feel the way you do about your friend - you, too, can be effortlessly thin. And you won't be tired and without energy if you take the right dose. That's different for everyone. I felt no energy the first few weeks I was on it- turns out, the starting dose was strong enough for me to almost completely lose my appetite, and so I was only eating around 700 calories/day. Of course I had no energy! Now on 1 mg/week I'm eating about 1800 calories/day and I am totally satisfied. Before the GLP, I could easily eat 3000 calories/day and still be hungry. My mission when I first started this was to lose the 15 pounds I'd been unsuccessfully trying to shed, and then stop. But I now have no problem with taking this forever, because it's just so freeing to no longer obsess about food, to no longer argue with myself about whether I'm going to finish all my meal, about whether I'm going to order dessert, about whether I'm going to power through going to bed hungry. Now, I eat everything I want in whatever quantity I want - the difference is, this med has changed my brain/stomach into wanting much less. It is a miracle and I never want to go back to the way I used to be. |
Hello, I was you! Always slim but it was torture to stay that way. Always walking around with a headache because I was hungry, always totaling up my calories in my head and feeling depressed when I was out of calories and had to go to bed hungry. Spent three decades living like this, but it was worth it to me to remain thin. I went to a med spa initially for my GLP. I wore a heavy coat, big sneakers, and on my application, wrote down that I was 3 inches shorter than I actually am. They weighed me, but I could tell they really couldn't care less whether I medically qualified - I got the feeling that if you have a pulse, you're a candidate for GLPs. After she wrote my prescription, I did ask the nurse if there was a cut off for qualification, and she said you have to be above 19 BMI. I was about 21 BMI when I started, now I am 19. I switched to an online pharmacy and I do lie about my weight on there in order to qualify. I take a microdose now and it's been totally life changing. I truly mourn all the years I felt starved and deprived and hating myself when I would fall off the wagon and eat something bad...all those years I spent counting calories, obsessively weighing myself. Ugh. That's all a thing of the past on the GLP. |
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I know people on here say GLP1s are for lazy people, but I'm more active than ever on one. In fact, I've been running regularly and getting faster and faster. I now love how I look and feel, eat very well too (I never ate poorly though).
If I had told my younger self that I'd one day be thin, feel great, love my body, not feel guilty about food ever and run 5ks willingly and regularly and at a good pace (and getting better!) I'd not have believed it for a second. |
This. Your forever will likely be longer if you take the glp. |
All the pro body builders who lift heavy and eat their 2g/lb protein still lose muscle during cut phase. |
NP here. My best friend is a doctor and has gone from obese (not sure of size but 18 sounds right) to probably a 4. It’s crazy. It’s also changed her personality but that’s another post. She has struggled with addiction in the past so was never the cruciferous vegetable-eating stereotype of an md. She had a horrible lifestyle. Still, I never would have believed the transformation. At least she is open about the medication with her patients. |
Because of where they're starting. But you're not a pro body builder and neither is the average person starting a GLP, so they can lose weight without losing muscle mass. |
How do you get this price and what is the med? Price has been a deterrent as well as a nightmare that there will one day be a shortage or stoppage of supply and everyone will balloon again! |
NP. I got that price last weekend for tirz as part of a first time introductory special, it's not really the going rate. But when you frame it this way, I am so happy I ordered because it really be more cost effective and healthier to do this vs spending money on food and being overweight. |