How bad is the rebound in terms of weight when you get off the weight-loss shots?

[Anonymous]

Stay on it, smallest dosage. People get rid of many medications thanks to the weight loss. It’s a metabolic hormone, if your body needs it why stop?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Op - I think I do have pretty decent habits - I’ve been on noom for awhile and track my eating pretty religiously and it’s not hard for me to stay at the bottom range of my calorie requirements and rarely exceed them.

I dont have a sweet tooth and am not much interested in desserts, I rarely drink, I don’t drink soda, eat fast food only occasionally, etc My problem has always been portion size and not going for seconds.

13 years ago, I had a bit of an issue with my heart and I very successfully lost 20-30lbs… and when I stopped being vigilant it crept back up, and since the pandemic I haven’t been able to make a dent. I’m more vigilant than I was 12 years ago, and like I said I struggle to lose 5-7 and last time I would lose 5-7 over the course of 7-8 weeks, have a few weeks of plateau and then go on to lose another 5, plateau, etc… this time the plateau is brief and is followed by an increase and I wind up back at square one.

I’m convinced my body chemistry has just changed as I’ve aged. I am fairly active - I do believe there is a difference between being fat and being unhealthy - I ride a bike to work several days a week, I hike, I never get less than 11k steps a day, etc and aside from slightly high blood pressure my heart is healthy - no cholesterol, no sign of diabetes etc My parents and grandparents were extremely long lived… But my ankles and knees hurt, I have apnea and as active as I am, my weight is definitely keeping me from being more active - I don’t want to be walking with a cane by the time I’m 55.

I feel like I could be healthier if I lost the weight, but I worry about the cost, shortages and the sense of being tied to something. I actually sleep like a baby with my cpap but that obligation to always have it and feel like I can’t travel or camp or visit friends or go overseas without it drives me crazy. The shot would probably allow me to ditch the cpap (my doctor has pretty confidently said losing 40 pounds would take care of the apnea symptoms) but it just sucks to think I’d be replacing it with another obligation.

It would also just be so demoralizing to lose the weight, feel great and then get slammed with a rapid increase. Especially if the reason I have to stop is beyond my control (shortages, cost, rfk jr)

I’m a guy and I also wonder if there’s a difference between men and women.

Have you tried strength training? You have the same reservations that I do about taking a drug for weight loss. I'm not saying it's bad for everyone, but I am trying diet cleanup and strength training first. Having a solid muscle mass foundation will supposedly help one lost weight, but more importantly it will definitely help you as you age.

Yup and I enjoy it. Core too. My concern with the training is that I’m actually building mass and upping my calorie requirements which makes it harder to figure out the right balance for weight loss. So I try to stick to body weight training instead of lifting, and try to improve my vo2max. And I think I’m a very muscular person who has coated himself in fat - I’m quite strong, and I think I have to be to drag around all this weight doing the stuff I want to do. I guess my goal is to be lighter and smaller, so I can be as active as I want - my knees really can’t deal with any more weight, even if it’s more muscle.

I don't understand what you're saying. If you weight train and lose weight, you have a higher chance of losing fat and retaining muscle. If you have bad knees, then you probably lack muscle around your quads and hamstrings. And if you don't weight train and lose what little muscle you have in your legs, then your knees don't stand a chance to all the cardio you're doing.

[Anonymous]

I started Mounjaro in Nov 2022 and stayed on 9 months or so and lost 30 lbs. I gained 5 back over the course of 18 months-- it was mostly water weight. I have just gone back on recently to lose my final 25 lbs hopefully. I don't like the way I feel on it so intend the meds to be temporary. My doctor is okay with me going off and on.

[Anonymous]

Is the regain from the medication itself, or the return to old food habits?

[Anonymous]

Anonymous wrote:

Anonymous wrote:I'm 44 and my body has just shut down on weight loss. I can spend weeks carefully counting calories and I'll slowly, slowly, slowly drop weight... but after about six pounds, the trend reverses itself. If I'm ever not extremely vigilant, it comes back in a hurry.

I've read a lot about how being overweight for an extended period of time will program your body to try and maintain that weight, and the older you are the more your body will resist weight loss, and I feel like the poster child for that.

The injections seem appealing, but I dont' want to lose 40-50 pounds and then have it all come back or increase. Also, being on an injection for the rest of my life just doesn't seem realistic.

Not so much.

The thing is once you gain a fat cell, you never lose it without surgery.

You can shrink a fat cell, but not get rid of it, so it is always there ready to swell up again.

I never knew this. Conversely, do you gain fat cells when you gain weight, or do the ones you already have just expand? If it’s the latter, then this statement seems nbd. If it’s the former, then holy h-ll, how do people who have gained weight ever really slim back down for good?
- NP

[Anonymous]

What's considered a small dose for maintenance?

[Anonymous]

Anonymous wrote:What's considered a small dose for maintenance?

I’d like to know too. Wonder if that is what people call “micro dosing”?

[Anonymous]

Anonymous wrote:Is the regain from the medication itself, or the return to old food habits?

Hungers cues are off when you age. I eat very healthy but I feel much more hunger so I gained on a healthy diet.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I started at age 60 when I gained a ton after being put on an SSRI. All I can say is this: The shots work, you lose weight slowly and effortlessly, and I’ll never look back. Go to a reputable weight clinic (my obgyn maintains one in her office) so you have real support and a long-term plan. Don’t wait! It’s truly a miracle drug.

An obgyn is not a reputable weight clinic.

This. So ridiculous.

[Anonymous]

Just need to point out, when people lose weight through WW, Jenny Craig, Nutrasystem, Atkins, whatever, they usually gain it back as well (anyone remember the TV show "the biggest loser"?)

That people regain the weight after going off the drugs shouldn't be a surprise to anyone, as it's what happens. I will say, the drugs are making the weight come off much easier

[Anonymous]

Anonymous wrote:Just need to point out, when people lose weight through WW, Jenny Craig, Nutrasystem, Atkins, whatever, they usually gain it back as well (anyone remember the TV show "the biggest loser"?)

That people regain the weight after going off the drugs shouldn't be a surprise to anyone, as it's what happens. I will say, the drugs are making the weight come off much easier

Yes, people who use trainers and eat body builder meals also gain back when they stop.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I'm 44 and my body has just shut down on weight loss. I can spend weeks carefully counting calories and I'll slowly, slowly, slowly drop weight... but after about six pounds, the trend reverses itself. If I'm ever not extremely vigilant, it comes back in a hurry.

I've read a lot about how being overweight for an extended period of time will program your body to try and maintain that weight, and the older you are the more your body will resist weight loss, and I feel like the poster child for that.

The injections seem appealing, but I dont' want to lose 40-50 pounds and then have it all come back or increase. Also, being on an injection for the rest of my life just doesn't seem realistic.

Not so much.

The thing is once you gain a fat cell, you never lose it without surgery.

You can shrink a fat cell, but not get rid of it, so it is always there ready to swell up again.

I never knew this. Conversely, do you gain fat cells when you gain weight, or do the ones you already have just expand? If it’s the latter, then this statement seems nbd. If it’s the former, then holy h-ll, how do people who have gained weight ever really slim back down for good?
- NP

Both, existing ones swell back up and excess intake beyond that encourages new fat cell production.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I'm 44 and my body has just shut down on weight loss. I can spend weeks carefully counting calories and I'll slowly, slowly, slowly drop weight... but after about six pounds, the trend reverses itself. If I'm ever not extremely vigilant, it comes back in a hurry.

I've read a lot about how being overweight for an extended period of time will program your body to try and maintain that weight, and the older you are the more your body will resist weight loss, and I feel like the poster child for that.

The injections seem appealing, but I dont' want to lose 40-50 pounds and then have it all come back or increase. Also, being on an injection for the rest of my life just doesn't seem realistic.

Not so much.

The thing is once you gain a fat cell, you never lose it without surgery.

You can shrink a fat cell, but not get rid of it, so it is always there ready to swell up again.

I never knew this. Conversely, do you gain fat cells when you gain weight, or do the ones you already have just expand? If it’s the latter, then this statement seems nbd. If it’s the former, then holy h-ll, how do people who have gained weight ever really slim back down for good?
- NP

Forgot to answer this one. They never get back completely to zero point. The fat cells are still there. Shrink them as much as possible, and you might look close to when before gaining those extra 5 lbs, but never as good. The people who look the most fit later in life, were always fit and never "let themselves go" at any point.

Liposuction will remove fat cells obviously, but there is also scarring and other risks and health or cosmetic issues associated with lipo, especially over large areas of the body.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Just need to point out, when people lose weight through WW, Jenny Craig, Nutrasystem, Atkins, whatever, they usually gain it back as well (anyone remember the TV show "the biggest loser"?)

That people regain the weight after going off the drugs shouldn't be a surprise to anyone, as it's what happens. I will say, the drugs are making the weight come off much easier

Yes, people who use trainers and eat body builder meals also gain back when they stop.

It’s 2025. Do people think they can stop eating/moving in the ways that made them lose weight and not regain weight?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I'm 44 and my body has just shut down on weight loss. I can spend weeks carefully counting calories and I'll slowly, slowly, slowly drop weight... but after about six pounds, the trend reverses itself. If I'm ever not extremely vigilant, it comes back in a hurry.

I've read a lot about how being overweight for an extended period of time will program your body to try and maintain that weight, and the older you are the more your body will resist weight loss, and I feel like the poster child for that.

The injections seem appealing, but I dont' want to lose 40-50 pounds and then have it all come back or increase. Also, being on an injection for the rest of my life just doesn't seem realistic.

Not so much.

The thing is once you gain a fat cell, you never lose it without surgery.

You can shrink a fat cell, but not get rid of it, so it is always there ready to swell up again.

I never knew this. Conversely, do you gain fat cells when you gain weight, or do the ones you already have just expand? If it’s the latter, then this statement seems nbd. If it’s the former, then holy h-ll, how do people who have gained weight ever really slim back down for good?
- NP

Forgot to answer this one. They never get back completely to zero point. The fat cells are still there. Shrink them as much as possible, and you might look close to when before gaining those extra 5 lbs, but never as good. The people who look the most fit later in life, were always fit and never "let themselves go" at any point.

Liposuction will remove fat cells obviously, but there is also scarring and other risks and health or cosmetic issues associated with lipo, especially over large areas of the body.

Thank you for answering my questions.

That is is depressing, I wish doctors would emphasize this when the scale starts to creep up.