It’s not my opinion. There is not a single study that shows anything, but rapid weight gain after going off the drug. It’s doesn’t reset your metabolism, it does not permanently curb your hunger. Once you go off you are back that the same place waging an uphill battle. It’s a lifetime drug if you want to stay a healthy weight and nobody know what decades of this stuff might mean. It’s not to say that will deter me from taking it. However people need to understand this won’t do a reset as calibrate claims. |
Correct. It doesn’t reset your metabolism. People with obesity continue to lose weight if they remain on semaglutide 2.4 mg after an initial 20 weeks of treatment, but gradually regain it if they switch to placebo, show the STEP 4 findings. The trial participants lost an average 10.6% of their starting bodyweight during the 20-week run-in period. After randomization, this trend continued in those who continued to take semaglutide, who lost an average 7.9% of bodyweight between weeks 20 and 68, whereas those who switched to placebo regained an average of 6.9%. This gave a 14.8 percentage point difference between the groups, which was statistically significant, report Domenica Rubino (Washington Center for Weight Management and Research, Arlington, Virginia, USA) and study co-authors. Over the whole trial from start of the run-in to week 68, people taking semaglutide lost an average of 17.4% of their starting bodyweight, whereas those who switched to placebo lost just 5.0%. |
I can't do Calibrate because I have federal insurance. I am from the US but live overseas and can likely buy the meds myself for much less than in the US. Same for bloodwork.
Any suggestions for something similar? |
Lots of people buy it OTC in other countries. In the FB group favorite countries are Mexico, Turkey, and Portugal. |
Thanks. I'd like to do it not just on my own, though. Calibrate won't even take you as self-pay. |
I think you are actually proving the PP's point - if you continue along this path (2 ice cream sandwiches!!), you will in fact rapidly gain back weight. Especially if your body is used to a lower calorie diet. |
NP. Would you stop with the moralistic and fake horror? Jesus, ignorant people like you are why the obesity epidemic is so bad. The fact is that PP has a biologically and metabolically different body than people who have never been obese. Her body and brain will drive her to eat in a way that normal weight people do not experience. That is what this drug changes: the biological signals driving obese people to eat. And that doesn’t change with weight loss, unfortunately. Weight loss doesn’t make an obese person metabolically the same as someone who is the exact same weight but who never was obese. Their bodies are completely different, on many levels. This should be regarded as a lifelong or very extended drug. Personally, I am convinced there is a state of pre-pre-diabetes that isn’t detected by A1C but that is common among obese people, and I think these drugs essentially treat that. Off the drugs, regardless of actual weight, the body reverts to that insulin-seeking pre-pre-diabetic state. We know so very little about the physiology and metabolism of obesity, in part because people so desperately want to make a medical condition into a moral condition. |
I’m that poster eating two ice cream bars. Thank you so much for chiming in. I’m trying really hard not to go back to where I was, and I’m not going to continue on that path. I’m staying in the gym and I know I have to stop buying this stuff! I know better. Those are the cues I was talking about. When I was on the medication I didn’t even want these types of temptations. Sigh… |
Gently, listen to yourself. Read what you wrote. Does it make sense? Does it sound logical? You are trying to control something without medication that was fully controlled with medication. This is not an issue of your willpower. This is an extremely complex issue of metabolism and physiological drive. You need to move away from this moralistic framework, because it will fail. Put another way, if you could continue on the path of no weight gain without medication, don’t you think you would have done it before Wegovy? |
According to the website it's $135/month or $1600/year. Can you pay for it out-of-pocket? |
Any way to get on this medicine if you do not have an overweight BMI? |
![]() Take your eating disorder elsewhere. |
Why are you so mean? I would never think to say this to someone. |
You already said something much, much meaner with your question. My God. Get some awareness. |
Stop being a jerk, this is a diabetes drug. Yes, I did. I gained some weight but not enough to make me overweight. My weight gain was from long term prednisone use, which destroyed my metabolism and made me prediabetic. I went back to my regular adult weight. I also did IF and keto with it and plan to stay on both indefinitely. My max dose was 1 mg and I was on ozempic. It won't turn you into a supermodel or get you to your HS weight, ar least not in my experience. |