It's from how they grow in the lab. Worst case scenario is total implantation failure with ICSI. That means you have a retrieval, then no embryos at all. Then if they fertilize, but don't divide properly or have a lot of fragmentation or arrest/die before the embryos make blast, then that's a sign of bad quality too. Or they can make blast and fail to implant or result in chemicals/miscarriages, or make blast and all come back abnormal. An ugly, poorly graded blast can still be normal and result in a healthy baby, so I'd call that ugly, but not bad. Bad means you get eggs, but can't get embryos that can make a baby. Total implantation failure could be a fluke, but twice and it probably means your eggs are just bad and donor eggs are your only option. Multiple cycles of not making blasts also means your eggs are probably just bad, though it's possible you could get EXTREMELY lucky like the PP above. Depending on insurance coverage and finances, most responsible RE's will say that 3 cycles is enough to know if your own eggs are going to work. You hear about people having success on their 5th cycle, but those are single digit odds and most people don't have the money or emotional bandwidth to keep putting your body through IVF cycles without any real chance of success. |
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I had my first at 40, tried for #2 at 41 1/2-42 yo, was told not going to happen (but was also told that with my first who I ended up conceiving naturally)... fast forward and I have been pregnant twice in the last year at 43 but both ended in miscarriage... am trying again now at 44... hugs to you OP
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| My heart goes out to eveyone here. I'm right there with you - 41 and have many rounds of IVF and losses behind me. I recommend the book It Starts with the Egg. I had a grand total of 1 blast from my first 3 rounds of IVF but got 9 blasts in my 4th and 5th combined after following the diet and supplements recs for 2 months prior to starting round 4. I still don't have a baby but I do believe this increased my odds. I also didn't test any of the 13 total embryos I've had transferred but am only transferring normal PGS embryos going forward to reduce the risk of more MCs. All of our stories are different but you are not alone in the struggle, OP. No need to explore other options until you feel it's time. Wishing you the very best and sending you a virtual hug. |
| Op any update? |
| OP here - DH was laid off so we lost coverage - I got a new job with surprise coverage (yay) but am now investigating changing clinics. We are trying naturally in the interim because why not and I’ve been keto for a month and focusing on losing weight (the lockdown 20 is real). Everyone is now pregnant around me, including a few w their third so I’m focusing on meditation and coping. |
Good luck, OP! We had a spontaneous pregnancy while switching clinics. Ours sadly ended in a MC, but I'm hoping for the best for you. Our old clinic said they see it happen all the time when women change things up and decide to switch. It's certainly worth a try. I also like Circle and Bloom's meditation for IVF as well. |