Alzheimer’s fraudulent data

Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

Start publicizing the known causes of chronic diseases, and start educating doctors and the public on how to AVOID making ourselves sick. But hell, there’s no profit in that. Get the cheap crap out of our food supply. Europeans don’t allow toxic additives in their food. Why do we? Profits over Health.

And yes, let school children grow some food outside. They’ll be more excited to eat it when they helped grow it. Promote CSAs and neighbored community gardening. Let’s get back to true healthy eating, garden to table.


Funny, I didn't know there was an established link between what you eat and Alzheimers.

I also have a child with a genetic disease and find the just eat healthy comments unhelpful, at times offensive.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

Start publicizing the known causes of chronic diseases, and start educating doctors and the public on how to AVOID making ourselves sick. But hell, there’s no profit in that. Get the cheap crap out of our food supply. Europeans don’t allow toxic additives in their food. Why do we? Profits over Health.

And yes, let school children grow some food outside. They’ll be more excited to eat it when they helped grow it. Promote CSAs and neighbored community gardening. Let’s get back to true healthy eating, garden to table.


Funny, I didn't know there was an established link between what you eat and Alzheimers.

I also have a child with a genetic disease and find the just eat healthy comments unhelpful, at times offensive.


Yeah, it's offensive. I don't know anyone who was more obsessed with healthy eating than my MIL, who now has severe Alzheimer's. Whatever it was, it wasn't diet.
Anonymous
Anonymous wrote:Unfortunate, but I'm not surprised. I saw a quote yesterday that's fitting -"A patient cured is a customer lost".


I know many people in healthcare and many people who work in pharma, and I don't know a single person who thinks that way. Can you imagine going into cancer research and devoting your life to it but all the time secretly hoping you don't succeed so people will continue to be sick? Or becoming a pediatrician and hoping sick kids stay sick so their parents will keep bringing them in?

It doesn't make sense, because it doesn't happen.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

Start publicizing the known causes of chronic diseases, and start educating doctors and the public on how to AVOID making ourselves sick. But hell, there’s no profit in that. Get the cheap crap out of our food supply. Europeans don’t allow toxic additives in their food. Why do we? Profits over Health.

And yes, let school children grow some food outside. They’ll be more excited to eat it when they helped grow it. Promote CSAs and neighbored community gardening. Let’s get back to true healthy eating, garden to table.


Funny, I didn't know there was an established link between what you eat and Alzheimers.

I also have a child with a genetic disease and find the just eat healthy comments unhelpful, at times offensive.


There are multiple factors that increase the risk of AD. There is research linking unhealthy diet and lack of exercise to an increased risk. Head injury too. And of course there are also multiple risk genes, some of which greatly increase the risk. Just because one person’s AD was likely caused by genetics doesn’t mean other cases aren’t due to lifestyle. It’s a complicated disease.
Anonymous
Anonymous wrote:Unfortunate, but I'm not surprised. I saw a quote yesterday that's fitting -"A patient cured is a customer lost".




“First do no harm” is long gone.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

Start publicizing the known causes of chronic diseases, and start educating doctors and the public on how to AVOID making ourselves sick. But hell, there’s no profit in that. Get the cheap crap out of our food supply. Europeans don’t allow toxic additives in their food. Why do we? Profits over Health.

And yes, let school children grow some food outside. They’ll be more excited to eat it when they helped grow it. Promote CSAs and neighbored community gardening. Let’s get back to true healthy eating, garden to table.


Funny, I didn't know there was an established link between what you eat and Alzheimers.

I also have a child with a genetic disease and find the just eat healthy comments unhelpful, at times offensive.


When someone uses the word "true" to describe something, you can safely ignore them. Any exceptions will be discarded as not true. No true Scotsman...
Anonymous
Anonymous wrote:
Anonymous wrote:Unfortunate, but I'm not surprised. I saw a quote yesterday that's fitting -"A patient cured is a customer lost".




“First do no harm” is long gone.


Do no harm makes surgery impossible. Is that the hill you want to literally die on?
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

Start publicizing the known causes of chronic diseases, and start educating doctors and the public on how to AVOID making ourselves sick. But hell, there’s no profit in that. Get the cheap crap out of our food supply. Europeans don’t allow toxic additives in their food. Why do we? Profits over Health.

And yes, let school children grow some food outside. They’ll be more excited to eat it when they helped grow it. Promote CSAs and neighbored community gardening. Let’s get back to true healthy eating, garden to table.


Funny, I didn't know there was an established link between what you eat and Alzheimers.

I also have a child with a genetic disease and find the just eat healthy comments unhelpful, at times offensive.


Yeah, it's offensive. I don't know anyone who was more obsessed with healthy eating than my MIL, who now has severe Alzheimer's. Whatever it was, it wasn't diet.


Yeah, but did she exercise? Just kidding! Both my mother and grandfather had dementia, and they both died at 75. I remember reading about a family where it went back many generations (everyone dead by 65 or something), but then all the sudden it skipped a generation. They were studying this woman to find out why. Those of us with strong genetic factors all hope we’re that lucky bastard.
Anonymous
Listen, anyone who understands how research is done in this country understands that it encourages falsifying data and publishing crap. All of these researchers have to hunt for grants and in order to save their jobs they must publish articles showing research results. It incentivizes poor practices. Of course there are many great researchers who care passionately about their causes but they have to make a living like everyone else. It’s a difficult business and there is way more data falsification than anyone wants to believe.
Anonymous
Anonymous wrote:Listen, anyone who understands how research is done in this country understands that it encourages falsifying data and publishing crap. All of these researchers have to hunt for grants and in order to save their jobs they must publish articles showing research results. It incentivizes poor practices. Of course there are many great researchers who care passionately about their causes but they have to make a living like everyone else. It’s a difficult business and there is way more data falsification than anyone wants to believe.


Yes. And this is one of the reasons it's frustrating to hear people say to sit down and trust the experts. Don't question the Science. Don't try to apply critical thought.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Having been to several medical conferences (not a doc) I've seen how Pharma companies play up to docs -- it's disgusting and docs don't seem to notice, perhaps because they feel they deserve such homage.
Anonymous
Anonymous wrote:
Anonymous wrote:Listen, anyone who understands how research is done in this country understands that it encourages falsifying data and publishing crap. All of these researchers have to hunt for grants and in order to save their jobs they must publish articles showing research results. It incentivizes poor practices. Of course there are many great researchers who care passionately about their causes but they have to make a living like everyone else. It’s a difficult business and there is way more data falsification than anyone wants to believe.


Yes. And this is one of the reasons it's frustrating to hear people say to sit down and trust the experts. Don't question the Science. Don't try to apply critical thought.


Keep in mind that the experts are not always scientists trying to keep their jobs, but can be MD's trying to pay off their med school loans.

Common sense is needed too.


Anonymous
This article does a great job of showing how even before this latest development, there were signs that too much emphasis was being placed on the amyloid hypothesis. https://www.statnews.com/2019/06/25/alzheimers-cabal-thwarted-progress-toward-cure/

RIP Sharon Bagley
Anonymous
Anonymous wrote:This article does a great job of showing how even before this latest development, there were signs that too much emphasis was being placed on the amyloid hypothesis. https://www.statnews.com/2019/06/25/alzheimers-cabal-thwarted-progress-toward-cure/

RIP Sharon Bagley


That’s a horrifying article. Thanks for sharing.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:can someone please summarize so we don't have to go to the links?


OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?


Having been to several medical conferences (not a doc) I've seen how Pharma companies play up to docs -- it's disgusting and docs don't seem to notice, perhaps because they feel they deserve such homage.

What a massive scam.
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