Alzheimer’s fraudulent data

[Anonymous]

Have any of you been following this story about fraudulent data in one of the original seminal Alzheimer’s papers?

https://www.dailykos.com/story/2022/7/22/2111914/-Two-decades-of-Alzheimer-s-research-may-be-based-on-deliberate-fraud-that-has-cost-millions-of-lives

If it’s true, that is terrible!

[Anonymous]

Anonymous wrote:Have any of you been following this story about fraudulent data in one of the original seminal Alzheimer’s papers?

https://www.dailykos.com/story/2022/7/22/2111914/-Two-decades-of-Alzheimer-s-research-may-be-based-on-deliberate-fraud-that-has-cost-millions-of-lives

If it’s true, that is terrible!

More than terrible- tragic. 16 years of wasted effort on research and drug development, mis-categorized deaths, and money down the drain. Thanks for posting OP. I know that science develops with new information, but this seems like a case of fraud.

[Anonymous]

OP here. I found the original Science article that discusses the images. This seems really bad.

https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease

[Anonymous]

can someone please summarize so we don't have to go to the links?

[Anonymous]

Not to distract from this important update, but I read down in the comments that Viagra or Cialis for both men and women are better at keeping blood moving through the brain/flushing than anything else. And that exercise, sleep, and healthy diet are paramount.

I'm glad that a Dr at Johns Hopkins didn't push my dad toward Aducanumab because he would have gone that direction, dad fit the profile. It is not as simple as a pill (it is an infusion), so we were glad to avoid that as well.

This same Dr said *exercise*.

Alz is in my family tree so I'm hopeful they keep looking for a cure.

[Anonymous]

Anonymous wrote:can someone please summarize so we don't have to go to the links?

OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

[Anonymous]

If you are interested in the issue of fraudulent/manipulated images in scientific papers, this is a great article:

https://www.nature.com/articles/d41586-020-01363-z

[Anonymous]

This isn’t news is it?
I thought this came out a while back.

[Anonymous]

Anonymous wrote:

Anonymous wrote:can someone please summarize so we don't have to go to the links?

OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?

[Anonymous]

Anonymous wrote:

Anonymous wrote:can someone please summarize so we don't have to go to the links?

OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

My mother and DH's father had Alzheimer’s. I'm disgusted.

I bet those rx companies also got money from the feds to create those drugs.

The conspiracy theorist side of me thinks they did it on purpose so that they could bilk millions of people and the government on drugs.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:can someone please summarize so we don't have to go to the links?

OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

My mother and DH's father had Alzheimer’s. I'm disgusted.

I bet those rx companies also got money from the feds to create those drugs.

The conspiracy theorist side of me thinks they did it on purpose so that they could bilk millions of people and the government on drugs.

There really needs to be an investigation to uncover exactly what’s going on - how much money they’ve received and from which sources, plus how it’s been used. There no objective oversight right now.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:can someone please summarize so we don't have to go to the links?

OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?

Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Have any of you been following this story about fraudulent data in one of the original seminal Alzheimer’s papers?

https://www.dailykos.com/story/2022/7/22/2111914/-Two-decades-of-Alzheimer-s-research-may-be-based-on-deliberate-fraud-that-has-cost-millions-of-lives

If it’s true, that is terrible!

More than terrible- tragic. 16 years of wasted effort on research and drug development, mis-categorized deaths, and money down the drain. Thanks for posting OP. I know that science develops with new information, but this seems like a case of fraud.

It is so upsetting. All that wasted time, effort and money. Alzheimer's is such a cruel disease.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:can someone please summarize so we don't have to go to the links?

OP here. It looks like one of the core early papers about Alzheimer’s that has guided billions of research money was fraudulent. People are speculating that’s why Alzheimer’s drug development has not been very successful.

Huge scandal if true.

Most of us have seen in recent years how common it is for pharmaceutical corporations to fund medical research. Why is this legal?

Big pharma isn't the culprit here. Pharma companies are rarely to never linked to this type of data falsification--they have too much at stake financially. This kind of falsification seems to happen most often among researchers in academia who need to publish to get grants, tenure, etc. It's a particular problem in China where researchers often have unrealistic, unattainable publishing quotas they must fulfill.

Also, pharma R&D is where a lot of new drugs come from. Without that, you have no new treatments and drugs.

Start publicizing the known causes of chronic diseases, and start educating doctors and the public on how to AVOID making ourselves sick. But hell, there’s no profit in that. Get the cheap crap out of our food supply. Europeans don’t allow toxic additives in their food. Why do we? Profits over Health.

And yes, let school children grow some food outside. They’ll be more excited to eat it when they helped grow it. Promote CSAs and neighbored community gardening. Let’s get back to true healthy eating, garden to table.

[Anonymous]

Unfortunate, but I'm not surprised. I saw a quote yesterday that's fitting -"A patient cured is a customer lost".