Do you think stimulants permanently affected your child?

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Anonymous wrote:Looks like there may be a higher risk of obesity with long term stimulant use....

https://newsatjama.jama.com/2014/03/17/long-term-stimulant-use-may-boost-obesity-in-children-with-adhd/

The problem with this kind of study is that the more severely effected kids are more likely to take medication. Is the obesity effect from the medication or due to poorer impulse control they would have had anyway?

Personally, I am more worried about neurological damage that could not be attributed to ADHD itself or an existing comorbidity.


This has been shown in rat brains but people aren't rats.


What has been shown? That rats taking doses equivalent to human therapeutic doses have observable neurological impairments?


For example: http://www.jneurosci.org/content/17/21/8491

The rats were given higher doses than equivalent therapeutical doses in humans, so this study is more about drug abuse than ADHD treatment.


These are low doses. https://www.ncbi.nlm.nih.gov/pubmed/14686913

Ok, but that's only a short term followup, and the changes appear to be positive.
"These data suggest that clinical doses of stimulant drugs may be acting as a trophic support at the glutamatergic synapses, thereby enhancing dopamine-glutamate interactions in the prefrontal cortex."
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