Penguinsix --- again

Anonymous
Did you find out any addional info re: the hives all the poeple in the other thread are reporting? I thought you said you looked into it, or were going to? Is there any way yo find out via VAERS or something if these reactions are related to a particular manufacturer?

Also, what is betapropiolactone in the Novartis one? Googling it makes it sound extremely scary!

Thanks...
Anonymous
Just FYI - my child broke out in hives this weekend - we have not done flu shots yet (we are waiting for our pediatrician to get more in) and she has not had any other vaccines in a few months. The pediatrician said it was caused by a mild virus, and not to worry about it.

We are on day 3 - they come and go, look horrible, disappear. Hives are weird but I've had them too (also several years since I have had any shots). They seem to have many causes, and the pediatrician said hives are very common in toddlers.
Anonymous
Who ever you are! I really learning a lot from you.
Thank you very much "Penguinsix"
Anonymous
penguinsix wrote:Hi

This is the search form for VAERS, though it is slightly complicated and easy to screw up (which is what I have done many times trying to do some more searches)

http://wonder.cdc.gov/vaers.html

What I have seen recently is that:

There have been 241 reports of Urticaria (of all sorts) for the H1N1 vaccine (I think they are currently through Novemeber 13)
There have been 357 reports for the seasonal flu vaccine in 2009. Over 3,072 over the history of the VAERS reporting system

However, if you search for "hives" in a more general sense you find:

2,325 for the H1N1 for 2009
4,804 for the seasonal flu vaccine in 2009

I think the difference might come because of doctors and medical professionals reporting "Urticaria" and regular people reporting "Hives". Some other interesting bits to remember include the fact that by and large, the people getting H1N1 shots at this time are youths, whereas the seasonal is being administered to the whole population across all age groups. (No, I don't know how many of either have been given but it would be interesting to compare). Would make me wonder if the higher numbers for the seasonal are based on more people getting the shots, or it affecting adults in a different way than youngsters. I don't have an answer to that one.

I guess I should also note that VAERS is a self-reported system so it's designed to give researchers a bit of an idea of what is occurring but it is not an exact science as to how much of something is or is not happening. For example, the one report about a person who turned into Wonder Woman or the Incredible Hulk should probably be ignored (some guys did that as a test of the system).

http://leftbrainrightbrain.co.uk/?p=342

I actually wanted to get a download of the whole database (which is available) but really haven't had the time to get into it (some serious database type stuff and I have a bunch of other database stuff on my plate that actually pays so I should be doing that). I'm not sure if you can break it down by manufacturer or not but suspect at some level you could.

As for betapropiolactone, I think you'll find more information if you search for it as two words: beta propiolactone or beta-propiolactone. I should warn you that most of the stuff you'll find is from "the sky is falling" crowd. In the H1N1 I believe it is what is actually used to kill the influenza virus, to "inactivate" it as they say. It is also used in rabies vaccines to inactivate the rabies and like many other ingredients, if you were to a bath in it probably wouldn't be the best thing to do. http://www.epa.gov/ttn/atw/hlthef/propiola.html

But like everything in medicine it is all about the dosage. Water can kill you if you drink too much of it (i.e. not drowning but by dilution of other nutrients). If you look at the amounts of beta-propilactone or any of other trace elements in the vaccine you'll find they are relatively miniscule. The vaccine guidelines from the FDA mentions that beta-propiolactone might be residually left over from the manufacturing process, so the amount in the final vaccine (if any) would be trace.

I did find an interesting observation here as it relates to the general proceess of using beta propiolactone in the manufacturing of HIV vaccines. I saw another site that mentioned it was the same process with influenza but I didn't really trust the site as it had a bunch of slight odd comments both pro and con:

http://www.biomanufacturing.org/pdf/bioprocess2005.pdf

Following inactivation, treated material was gradually heated over a period of 24 hours to 37 °C ± 0.2 °C within a pH range of 7.00 ± 0.5. The temperature was then maintained for an additional five hours (Table 1). This increase in temperature facilitates the complete hydrolysis of any remaining ßPL into an isomer of lactate and beta-propionic acid derivatives, both of which are innocuous compounds. Focusing on this requirement, validation of the use of ßPL for viral inactivation is a critical safety issue.


Apparently, though I am not a chemist, the process of heating the vaccine led to the hydrolysis of the ßPL (which is the weird way they refer to it in chemist lingo) and rendering it harmless. Again there may be a very very slight trace, but it is not of such a level that I'm concerned (but hey, that's me, you can judge for yourself). I would concur that a google search of that or any other "Toxin" as they are describe will lead to quite a few scare stories and panic inducing Fear, Uncertainty and Doubt. There are some scientists calling for some studies, but mainly relating to exposure of the vaccine manufacturer's employees (guess they are concerned about their colleagues) as they might inhale some of the material while making the vaccines.

But, for an interesting take on why you are reading about beta propilactone or Aluminum or <insert the random 'Toxins' of the week that the some screaming about> I would encourage you to read this interesting piece about the new tactics of some on vaccines:

http://www.theness.com/neurologicablog/?p=1054

The target they go after seems to change every week.

Good luck with your decisions.

fwiw my kids had no reaction other than a bit of crying after the needle. As I mentioned before a lollipop cured that. Will be getting the second shots in the next week or so.

Op here -- thank you SO MUCH! I value and appreciate your input so much. Thank you.
Anonymous
penguinsix wrote:As I've said in other posts, I am NOT a medical professional and you should take my comments with a grain of salt and skepticism that I expect you to apply to anything you read on the Internet. I try to provide links for your own further inquiry but when it comes to medical decisions for your kids please talk to your doctors and do some rational medical research about pros and cons of specific treatments. Google (can be) your friend provided you avoid the trap of confirmation bias (aka a closed mind) seeking rather to reinforce whatever belief you have rather than learning more about an issue.

As I've also said, I really don't care if your kids get a shot or not, but I would hope that when you make the decision you do so rationally and scientifically, without caving into emotional appeals to fear, uncertainty and doubt that are thrown up by some in this debate. It's really a shame this debate has turned more into an episode of Crossfire instead of something more informative and intellectually stimulating.

More here:

http://www.dcurbanmom.com/jforum/posts/list/78406.page
http://penguinsix.com/2009/11/12/the-war-on-science-and-rational-thought-time-to-join-the-fight/


I understand. They are well thought through and find pertinent links that I don't seem to have the time to find. So for that I thank you!
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