Chances at 42

[Anonymous]

What are the chances of getting pregnant at 42 with a Pgs tested embryo, frozen at 40?

[Anonymous]

My dr gave me pretty specific odds when I asked.

[Anonymous]

Should be the same as any PGS normal embryo. Most RE's say 60-70 percent chance of implantation.

(If you didn't have the PGS embryo, my answer would have been "slim.")

[Anonymous]

Have you had a successful pregnancy from that cycle? If so, I’d say the odds are in your favor.

[Anonymous]

My RE quoted me 80%

PGS tested embryo with good morphology.

Age was my only issue, so presumably the reason I didn't get pregnant before was aneuploidy.

[Anonymous]

Assuming you're a normal 42, very good. Age makes it hard to get a normal embryo, but once you have that, age isn't much of an issue. Good luck!

[Anonymous]

Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.

[Anonymous]

Anonymous wrote:What are the chances of getting pregnant at 42 with a Pgs tested embryo, frozen at 40?

I delivered two healthy babies from a single IVF cycle at 41.

[Anonymous]

Anonymous wrote:Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.

oh my, did your RE have ideas as to why?

[Anonymous]

Anonymous wrote:

Anonymous wrote:Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.

oh my, did your RE have ideas as to why?

No good answers. We moved on to DE.

[Anonymous]

Anonymous wrote:Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.

Op here - I am so sorry about this. I haven’t tried with mine yet. This is what’s confusing: they say that an euploid embryo has 60% implantation chance regardless of age, barring any anatomical issues.
REs always blame age for chromosome issues, but wouldn’t PGS eliminate that issue?
REs seem to have no problem with age when it comes to DE.
But if you have two PGS tested, normal embryos, one from an older woman, one from a younger why don’t the ones from older don’t take (in this equation the uterus is the same age for both)?

[Anonymous]

you will have a decent shot but nobody knows the odds though some will pretend they do
at the end of the day you will either be pregnant or not 99% odds won’t mean anything if you aren’t pregnant
PGS doesn’t test for everything - in average PGS tested embryo from a younger person is better than from an older person
There is a theory that older women reproductive system is more selective and will abort more embryos just to be safe - that explains why while mc rates are much higher for older women when the children are born there are really not that many differences between ages

[Anonymous]

Anonymous wrote:

Anonymous wrote:Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.

Op here - I am so sorry about this. I haven’t tried with mine yet. This is what’s confusing: they say that an euploid embryo has 60% implantation chance regardless of age, barring any anatomical issues.
REs always blame age for chromosome issues, but wouldn’t PGS eliminate that issue?
REs seem to have no problem with age when it comes to DE.
But if you have two PGS tested, normal embryos, one from an older woman, one from a younger why don’t the ones from older don’t take (in this equation the uterus is the same age for both)?

this is not true. PGS normal embryos have lower chances of implanted among older than among younger women. the difference is not huge but it exists. there are plenty of charts online you see for yourself.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.

Op here - I am so sorry about this. I haven’t tried with mine yet. This is what’s confusing: they say that an euploid embryo has 60% implantation chance regardless of age, barring any anatomical issues.
REs always blame age for chromosome issues, but wouldn’t PGS eliminate that issue?
REs seem to have no problem with age when it comes to DE.
But if you have two PGS tested, normal embryos, one from an older woman, one from a younger why don’t the ones from older don’t take (in this equation the uterus is the same age for both)?

PGS has limitations. It doesn't detect mosaicism only aneuplody. In layman's terms, it detects only if a chromosome is missing or there is an extra one. There are genetic abnormalities that have the correct number of chromosomes, but are still abnormalities. PGS can't catch that. In an older woman the frequency of genetic abnormalities in eggs is much higher than in a younger woman, statistically. Hope that answers your question.

Additionally, there are other reasons why implantation may not be happening. I have 3 transfers of PGD tested DE embryos and not even a chemical pregnancy. I am healthy, no anatomical abnormalities, no immune issues, textbook thyroid, etc., etc. Doctors can't find anything wrong, all they can say is keep trying. So while on average, globally, PGD tested FET may have a 60% chance of resulting in live births, it doesn't mean the outlook is like this for every single person.

[Anonymous]

I'm almost 42 and TTC as well OP. I got pregnant at 35 quickly and easily, had an easy pregnancy and natural delivery, and have a healthy 5 year old.

I've been TTC #2 for 4 years already. We already did IUIs and IVFs from age 38-40, none of them worked. Now have been trying on our own for the last 2 years, as I'm done with infertility treatments. I think my chances are slim to zero. Dr. said 1% chance for getting pregnant naturally when I was 39. However, he also said less than 10% chance for IVF.

I was diagnosed with unexplained secondary infertility (from 2 REs), mild DOR (from 2 REs) and immune issues from Dr. Abassi.

I have regular 28 day cycles and seem to ovulate every cycle. Other than low AMH the rest of my numbers are great and no issues with DH. Neither of us have any health issues.