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[quote=Anonymous][quote=Anonymous][quote=Anonymous]Have you had prior success from that cycle? We had 3 PGS normals frozen at age 39-40 but none took at 41-42.[/quote]

Op here - I am so sorry about this. I haven’t tried with mine yet. This is what’s confusing: they say that an euploid embryo has 60% implantation chance  regardless of age, barring any anatomical issues.
REs always blame age for chromosome issues, but wouldn’t PGS eliminate that issue?
REs seem to have no problem with age when it comes to DE.
But if you have two PGS tested, normal embryos, one from an older woman, one from a younger why don’t the ones from older don’t take (in this equation the uterus is the same age for both)?[/quote]

PGS has limitations. It doesn't detect mosaicism only aneuplody. In layman's terms, it detects only if a chromosome is missing or there is an extra one.  There are genetic abnormalities that have the correct number of chromosomes, but are still abnormalities. PGS can't catch that. In an older woman the frequency of genetic abnormalities in eggs is much higher than in a younger woman, statistically. Hope that answers your question.

Additionally, there are other reasons why implantation may not be happening.  I have 3 transfers of PGD tested DE embryos and not even a chemical pregnancy. I am healthy, no anatomical abnormalities, no immune issues, textbook thyroid, etc., etc.  Doctors can't find anything wrong, all they can say is keep trying.  So while on average, globally, PGD tested FET may have a 60% chance of resulting in live births, it doesn't mean the outlook is like this for every single person.[/quote]

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