Any over 35 moms elect for CVS/Amnio after negative NIPT results?

[Anonymous]

I delivered at 36, no impulse to do further testing after NIPT came back clear. TTC again (/still) at now 41, and probably would do a CVS this time because odds are different. Don't judge anybody for feeling one way or the other.

[Anonymous]

Anonymous wrote:To the poster who revived this thread -- I will also be 39 at the time of birth, had entirely unremarkable/non-concerning NIPT results, and had an amnio nonetheless. (We initially planned and tried to have a CVS, but due to placenta placement couldn't have the procedure and needed to wait until we could have the amnio.) Fortunately, the amnio results were also reassuring, but I would 100% do it again. For us, the risk of an issue with the baby was less tolerable than the risk of a miscarriage from the CVS or amnio. The NP we spoke with at our OB practice did gently try to talk us out of it. No one at Sibley MFM, where we had the failed CVS and the subsequent amnio, questioned our decision.

This is extremely helpful to know - thank you.

Did you make a separate appt w/ Sibley MFM or were you already under their care? did your OB office refer you? Right now only seeing my OB and am only 10 weeks so a few things need to happen for this question to be relevant, but I am preparing.

I am very happy you had reassuring results.

[Anonymous]

I felt very comfortable and grateful for the NIPT and the 12 week scan. I would have happily done an amnio if something had indicated it, but I saw no reason to take on a small risk for a very small risk, if that makes any sense. You can’t prevent all catastrophes.

[Anonymous]

To me, the main risk of CVS/Amnio isn’t miscarriage, it’s getting inconclusive results and then either 1) terminating what would otherwise have been a healthy baby or 2) going through your the rest of your pregnancy incredibly stressed about a genetic abnormality that turns about to be totally inconsequential. The likelihood of a Variant of Unknown Significance (VUS) is actually quite high so if you opt to do it, know that you may be opening a Pandora’s Box.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Skipped right to the CVS. It was fine.

Thanks. Just curious, why CVS and not amnio?

It can be done much sooner. If you want to TFMR it will be easier.

[Anonymous]

Anonymous wrote:

Anonymous wrote:To the poster who revived this thread -- I will also be 39 at the time of birth, had entirely unremarkable/non-concerning NIPT results, and had an amnio nonetheless. (We initially planned and tried to have a CVS, but due to placenta placement couldn't have the procedure and needed to wait until we could have the amnio.) Fortunately, the amnio results were also reassuring, but I would 100% do it again. For us, the risk of an issue with the baby was less tolerable than the risk of a miscarriage from the CVS or amnio. The NP we spoke with at our OB practice did gently try to talk us out of it. No one at Sibley MFM, where we had the failed CVS and the subsequent amnio, questioned our decision.

This is extremely helpful to know - thank you.

Did you make a separate appt w/ Sibley MFM or were you already under their care? did your OB office refer you? Right now only seeing my OB and am only 10 weeks so a few things need to happen for this question to be relevant, but I am preparing.

I am very happy you had reassuring results.

Our OB's office referred us to Sibley MFM. I'm not sure if we needed the referral, but it was provided to us. Good luck, whatever you decide!

[Anonymous]

Yes you can just ask for referral to Sibley mfm. For what it’s worth, they recommended against cvs/amnio for us based on nipt, ultrasound and genetic carrier history reports.

[Anonymous]

Anonymous wrote:I got my NIPT results last week and everything is negative, thankfully. But I know that is just a screening and not a diagnostic test. I am considering doing a CVS/amnio for more certain results, but of course I do not want to risk m/c (although I understand that risk is extremely low with an experienced MFM). I'm going to see what my MFM says next week at my NT scan (I will be exactly 12 weeks then). Just curious how other AMA moms made this decision. I will be 37 at EDD.

Not only did I have a CVS with all my pregnancies, I had one with a fully pgs tested one. I generally advise all my friends not to waste time on screening. Diagnostics only.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I'm the OP of this thread and I'm now 17 weeks along. my NT scan came back totally normal and both my MFM and OB recommended against CVS/amnio at this point, so I followed their rec. My MFM did say that if anything concerning comes up at the anatomy scan, we could revisit doing an amnio at that point.

Thanks for the update. Glad you went with what the OB and MFM said (which is what several of us were telling you).

NIPT/Nuchal are Screenings. They are in no way diagnostic. Had a friend under 35 have both and both looked good and gave birth to a baby with Down's syndrome.

But also they only screen for a couple of things. An amnio can catch much more. I don't understand why people are so afraid of amnios. The risk of a complication from it so absurdly low. And even lower with an extremely experienced doctor. The fear mongering over amnios really needs to stop. I had people tell me "the needle is so huge, it's so painful etc...). The needle is a regular size, the actual test lasts under a minute and the pain was extremely minimal (really not even pain-just weird/uncomfortable). And even with amnio and even with extended microarray you still can't test for EVERYTHING but I wanted to test for everything that I could.

I am reviving this thread bc it’s an issue I expect I may be grappling w/ in a few short weeks.

First of all, I am really worried abt my OB trying to ‘talk me out of’ an amnio. I am still waiting on my NIPT results, so all very premature right now (obvi if NIPT suggests something, I am sure my dr will recommend amnio). But assuming the NIPT suggest very low risk, I really want to have the confidence to demand I get the amnio. This is information I very much want and I agree that the discussions of the risks of the amnio are highly unscientific. People cite “Risks” but w/ no data, context or anything. Really don’t find the discussion of the risks compelling at all.

Second though, while i understand the NIPT is NOT diagnostic, why does my dr sheet on it say that it’s 99% accurate for Down syndrome? How could that be? Down syndrome is not the only thing I care about, so regardless of that, I want the amnio but I am curious given all the statements on this thread abt how the NIPT isn’t diagnostic. If it’s right 99% of the time abt presence of Down’s syndrome, that’s pretty meaningful. Again, does not change my view of amnio as I am not only interested in Down’s

I don’t understand. Why does your doctor get a vote in this? Just tell her or him you want to do it and that’s it.
Also, have a CVS, don’t wait for amnio.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I'm the OP of this thread and I'm now 17 weeks along. my NT scan came back totally normal and both my MFM and OB recommended against CVS/amnio at this point, so I followed their rec. My MFM did say that if anything concerning comes up at the anatomy scan, we could revisit doing an amnio at that point.

Thanks for the update. Glad you went with what the OB and MFM said (which is what several of us were telling you).

NIPT/Nuchal are Screenings. They are in no way diagnostic. Had a friend under 35 have both and both looked good and gave birth to a baby with Down's syndrome.

But also they only screen for a couple of things. An amnio can catch much more. I don't understand why people are so afraid of amnios. The risk of a complication from it so absurdly low. And even lower with an extremely experienced doctor. The fear mongering over amnios really needs to stop. I had people tell me "the needle is so huge, it's so painful etc...). The needle is a regular size, the actual test lasts under a minute and the pain was extremely minimal (really not even pain-just weird/uncomfortable). And even with amnio and even with extended microarray you still can't test for EVERYTHING but I wanted to test for everything that I could.

I am reviving this thread bc it’s an issue I expect I may be grappling w/ in a few short weeks.

First of all, I am really worried abt my OB trying to ‘talk me out of’ an amnio. I am still waiting on my NIPT results, so all very premature right now (obvi if NIPT suggests something, I am sure my dr will recommend amnio). But assuming the NIPT suggest very low risk, I really want to have the confidence to demand I get the amnio. This is information I very much want and I agree that the discussions of the risks of the amnio are highly unscientific. People cite “Risks” but w/ no data, context or anything. Really don’t find the discussion of the risks compelling at all.

Second though, while i understand the NIPT is NOT diagnostic, why does my dr sheet on it say that it’s 99% accurate for Down syndrome? How could that be? Down syndrome is not the only thing I care about, so regardless of that, I want the amnio but I am curious given all the statements on this thread abt how the NIPT isn’t diagnostic. If it’s right 99% of the time abt presence of Down’s syndrome, that’s pretty meaningful. Again, does not change my view of amnio as I am not only interested in Down’s

I don’t understand. Why does your doctor get a vote in this? Just tell her or him you want to do it and that’s it.
Also, have a CVS, don’t wait for amnio.

I understand it should be my decision, but as several others on the thread have suggested, some OBs do discourage it (when not suggested in view of other testing) and fine I will ignore my OB if she does that, but I like to work in harmony w my doctors when possible.