Ivf questions to ask

Anonymous
Anonymous wrote:Different perspective than I've seen represented here: while trying for a second child, starting at 39, we tested the 1 or 2 embryos we got in the first 3 cycles, which seemed like a giant waste of time. Then we transferred untested embryos. I did end up having a miscarriage after one of those transfers, which landed me in the ER, but I wouldn't make a different choice, evening knowing that outcome. PGT is not reliable, b/c of the small number of cells that are being tested. So you are potentially discarding a normal embryo. And the best lab is your body, that actually does the work to sort out normal and abnormal embryos (hence miscarriages). I'm sure someone will come at me for all of this, but even at CCRM, with their amazing lab, my doc was still supportive of this choice.



I agree with you, it is not reliable. What was your dr’s perspective at ccrm?
Anonymous
The team at CCRM really emphasizes the quality of their lab, saying that their procedures, embryologists, and equipment are best-in-class, increasing the accuracy of testing. Which I didn't disagree with, and if I ended all my retrieval cycles with tons of embryos, I'd have tested them. But I didn't, and since the guidance over 40 is to transfer 2-3 embryos at a time, it seemed like the better option. You can't get pregnant if you don't put any embryos in, so at least I was giving myself a chance.
Anonymous
Anonymous wrote:The team at CCRM really emphasizes the quality of their lab, saying that their procedures, embryologists, and equipment are best-in-class, increasing the accuracy of testing. Which I didn't disagree with, and if I ended all my retrieval cycles with tons of embryos, I'd have tested them. But I didn't, and since the guidance over 40 is to transfer 2-3 embryos at a time, it seemed like the better option. You can't get pregnant if you don't put any embryos in, so at least I was giving myself a chance.


Were you able to get pregnant with those 3 embryos?
Anonymous
Anonymous wrote:
Anonymous wrote:The team at CCRM really emphasizes the quality of their lab, saying that their procedures, embryologists, and equipment are best-in-class, increasing the accuracy of testing. Which I didn't disagree with, and if I ended all my retrieval cycles with tons of embryos, I'd have tested them. But I didn't, and since the guidance over 40 is to transfer 2-3 embryos at a time, it seemed like the better option. You can't get pregnant if you don't put any embryos in, so at least I was giving myself a chance.


Were you able to get pregnant with those 3 embryos?



We had a very long journey. All together, we tested 4 embryos (across 4 retrievals, one retrieval didn't have any embryos make it to day 6), and then stopped testing and transferred a total of 9 embryos across 4 different transfers (2--this resulted in a miscarriage, 3, 3, 1). Only one was considered poorly graded (the last transfer) and I think it was a BB. I consistently made 1-3 highly graded embryos every time (except once), nothing normal and nothing stuck. We ended up using DE, after really struggling with whether that was the right decision for us, and ultimately, it was. We had a single embryo, did one transfer and had a healthy, uneventful pregnancy at 42/43.
Anonymous
Anonymous wrote:The statistics of success with your own eggs at 42 are poor. Start asking questions about donor eggs. (I’m not trying to be unkind, just realistic.)

You shouldn’t just randomly mention donor eggs! It is a HUGE decision on a very complicated and complex topic and it isn’t a solution for many many people due to their beliefs and principles! OP is interested in Own Eggs, if she was interested in donor she would have written it !
Anonymous
It’s not random, it’s a statistically accurate suggestion. Hopefully she’s successful with her own eggs, but it makes no sense to pretend that it is not problematic at her age.
Anonymous
Not all clinics will transfer embryos that came back w bad results like mosaicism. Know what your clinic does before testing. They may refuse to transfer or you might have agreed to discard in the paperwork.
Anonymous
Sorry. Bad results that could be mosaicism.
Anonymous
Anonymous wrote:
Anonymous wrote:The statistics of success with your own eggs at 42 are poor. Start asking questions about donor eggs. (I’m not trying to be unkind, just realistic.)

You shouldn’t just randomly mention donor eggs! It is a HUGE decision on a very complicated and complex topic and it isn’t a solution for many many people due to their beliefs and principles! OP is interested in Own Eggs, if she was interested in donor she would have written it !


Exactly. Op here, im not interested in donor eggs. If not successful with own eggs we will move on. Also my REI said she would not mention donor eggs for me with my stats when we haven’t tried yet
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:The team at CCRM really emphasizes the quality of their lab, saying that their procedures, embryologists, and equipment are best-in-class, increasing the accuracy of testing. Which I didn't disagree with, and if I ended all my retrieval cycles with tons of embryos, I'd have tested them. But I didn't, and since the guidance over 40 is to transfer 2-3 embryos at a time, it seemed like the better option. You can't get pregnant if you don't put any embryos in, so at least I was giving myself a chance.


Were you able to get pregnant with those 3 embryos?



We had a very long journey. All together, we tested 4 embryos (across 4 retrievals, one retrieval didn't have any embryos make it to day 6), and then stopped testing and transferred a total of 9 embryos across 4 different transfers (2--this resulted in a miscarriage, 3, 3, 1). Only one was considered poorly graded (the last transfer) and I think it was a BB. I consistently made 1-3 highly graded embryos every time (except once), nothing normal and nothing stuck. We ended up using DE, after really struggling with whether that was the right decision for us, and ultimately, it was. We had a single embryo, did one transfer and had a healthy, uneventful pregnancy at 42/43.

Thank you for sharing and congrats on that pregnancy. These decisions are always hard but seems like you ultimately made the right decision for you and it all worked out
Anonymous
Anonymous wrote:Not all clinics will transfer embryos that came back w bad results like mosaicism. Know what your clinic does before testing. They may refuse to transfer or you might have agreed to discard in the paperwork.


My REI said if we had mosaics , she wouldn’t necessarily discard them, we would need to understand what’s potentially affected, all the risks, options etc and decide at that time
Anonymous
A class action lawsuit was filed last week against pgta testing companies. More info here : https://www.progress.org.uk/class-action-lawsuits-against-genetic-testing-companies-over-pgt-a/
Anonymous
Anonymous wrote:
Anonymous wrote:My re said it wasn’t even worth it without doing icsi.

Icsi is only recommended if there are sperm issues. My RE did not recommend it for us


I did IVF at 41 without ICSI (no sperm issues). We did do assisted hatching on blasts. We have 2 kids from our 2nd cycle - singletons with 2nd by FET.
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