Recurring early miscarriage

[Anonymous]

Anonymous wrote:PP my story parallels yours a bit. I just want to give OP different perspectives since she is still trying to decide the course of action she takes and time is of the essence for her.

I'm also 40 now and started TTC about 10 years ago and had multiple losses (8). I went through with immune testing and ended up having four IVIG infusions, humira, intralipids, lovenox, Neupogen after SG tried to tell me to do IVF or possibly donor eggs. After all that, my subsequent 3 pregnancies were all successful (8, 6 and 4 years old now). Not all of those treatments worked the first time around but we learned more with each set of testing and were able to find what worked for me. Each successful pregnancy had some degree of placental issues though which confirms my diagnosis of immune issues. Some cytokines like TNF-a can impact egg quality so I think it's worthwhile to at least have initial testing done there. If you have already been to see Dr. Sacks then it should be less challenging to see Dr. Abbasi about immune testing (assuming they are both still at CFA).

OP here. I have an appointment coming up and plan to ask about further immune testing. Thanks for your story ! It gives me hope!!

[Anonymous]

Anonymous wrote:PP my story parallels yours a bit. I just want to give OP different perspectives since she is still trying to decide the course of action she takes and time is of the essence for her.

I'm also 40 now and started TTC about 10 years ago and had multiple losses (8). I went through with immune testing and ended up having four IVIG infusions, humira, intralipids, lovenox, Neupogen after SG tried to tell me to do IVF or possibly donor eggs. After all that, my subsequent 3 pregnancies were all successful (8, 6 and 4 years old now). Not all of those treatments worked the first time around but we learned more with each set of testing and were able to find what worked for me. Each successful pregnancy had some degree of placental issues though which confirms my diagnosis of immune issues. Some cytokines like TNF-a can impact egg quality so I think it's worthwhile to at least have initial testing done there. If you have already been to see Dr. Sacks then it should be less challenging to see Dr. Abbasi about immune testing (assuming they are both still at CFA).

This sounds a bit like me. Can you explain what you mean by placental issues?

[Anonymous]

Anonymous wrote:

Anonymous wrote:PP my story parallels yours a bit. I just want to give OP different perspectives since she is still trying to decide the course of action she takes and time is of the essence for her.

I'm also 40 now and started TTC about 10 years ago and had multiple losses (8). I went through with immune testing and ended up having four IVIG infusions, humira, intralipids, lovenox, Neupogen after SG tried to tell me to do IVF or possibly donor eggs. After all that, my subsequent 3 pregnancies were all successful (8, 6 and 4 years old now). Not all of those treatments worked the first time around but we learned more with each set of testing and were able to find what worked for me. Each successful pregnancy had some degree of placental issues though which confirms my diagnosis of immune issues. Some cytokines like TNF-a can impact egg quality so I think it's worthwhile to at least have initial testing done there. If you have already been to see Dr. Sacks then it should be less challenging to see Dr. Abbasi about immune testing (assuming they are both still at CFA).

This sounds a bit like me. Can you explain what you mean by placental issues?

First pregnancy growth was good until just after 38w when the placenta was aging. DD was born 6 pounds 8 ounces at 39w and was technically small for her gestation (according to the ped). 2nd pregnancy I was diagnosed with IUGR at 29w and put on bedrest plus a high protein 10k calorie a day diet and increased my lovenox dose. I went back on immune treatments at that time and was able to get DD2 up to 6 pounds 8 ounces by the time she was born at 38w5d. We sent that placenta off for testing, but was not conclusive what was wrong with it. With DS I had something called CVP (circumvallate placenta) which I was told is very rare and can increase risk for IUGR and abruption. When my MFM found that she called my immune doctor while I was in the office and discussed how he wanted to treat it. Freaked me out for sure, but we made it through and DS was born 38w6d over 8 pounds. It's safe to say it did not impact his growth at all.

[Anonymous]

Anonymous wrote:Hello everyone

This is OP. Just wanted to share an update. Every test I have taken has come back normal. Very frustrating.

I am waiting to see what happens this cycle ( I can test in a week). Per the doctors instructions I have added Baby Aspirin to my daily vitamin intake ( Prenatal, Vitamin D, Coq-10).

Good luck to everyone who has no answers but keeps trying!

I was in same situation several years ago between my two kids - multiple miscarriages, no abnormalities. Added baby aspirin and then immediately went on progesterone inserts when I got pregnant with my son and it worked. Good luck OP!