How many DE cycles is realistic?

[Anonymous]

Just wondering what's realistic for how many DE cycles it may take for success with DE?

[Anonymous]

One to two max.

[Anonymous]

Took 1 but depends on where you go. Look at stats and you will see some clinics are much better than others.

[Anonymous]

Once you reach 3 or 4 transfers (not cycles, but transfers), you're theoretically close to 100% odds. I personally would try at least two cycles with different donors in case there's some as-yet-undetectable incompatibility between you & the donor or your partner & the donor.

[Anonymous]

It varies! For me, the first try worked but others I know are still trying. SG offers the six tries for one flat rate thing which seems to suggest they are pretty sure you will have success within 6 transfers. But there is always the unknown!

[Anonymous]

We did one cycle, but two transfers. (One egg retrieval - fresh transfer failed, frozen blasts resulted in kids.)

GOod luck OP.

[Anonymous]

Cycle 1: Donor's 1st donation= entire cycle sucked + BFN

Cycle 2: Repeat donor= BFP

[Anonymous]

18:54 again, technically every transfer is a new roll of the dice, but if you want to calculate cumulative odds of success, I believe it works like this (anyone out there who knows better feel free to correct my math!):

At SG, odds of clinical pregnancy for a single embryo transfer using DE VF are 60%.

So, say you have a fresh eSET, you have a 60% chance of pregnancy, with a 40% chance of a BFN.

If you did a second fresh cycle, you would calculate 60% times the 40% chance of a BFN (.60 x .40), which is 24%, and add that to the first cycle's 60%.

So for the two fresh cycles combined, your cumulative odds of success are 84%.

For a third fresh cycle, you'd calculate 60% of the remaining 16% chance of a BFN (.60 x .16), which is 9.6%, and add it to the 84%, so the cumulative odds of a clinical pregnancy over three cycles would be 93.6%.

For a fourth fresh cycle, you'd add 60% of the remaining 6.4% chance of a BFN (.60 x .064, or 3.84%), so now your cumulative odds are greater than 97%.

A fifth fresh cycle gets you close to 99%, while a 6th puts you over 99% (which is presumably why SG's money-back quarantee covers up to 6 cycles).

(Note that your cumulative odds NEVER reach 100% -- they get closer and closer to 100, but there's always a slim chance that an infinite number of cycles would still result in a BFN.)

[Anonymous]

Anonymous wrote:18:54 again, technically every transfer is a new roll of the dice, but if you want to calculate cumulative odds of success, I believe it works like this (anyone out there who knows better feel free to correct my math!):

At SG, odds of clinical pregnancy for a single embryo transfer using DE VF are 60%.

So, say you have a fresh eSET, you have a 60% chance of pregnancy, with a 40% chance of a BFN.

If you did a second fresh cycle, you would calculate 60% times the 40% chance of a BFN (.60 x .40), which is 24%, and add that to the first cycle's 60%.

So for the two fresh cycles combined, your cumulative odds of success are 84%.

For a third fresh cycle, you'd calculate 60% of the remaining 16% chance of a BFN (.60 x .16), which is 9.6%, and add it to the 84%, so the cumulative odds of a clinical pregnancy over three cycles would be 93.6%.

For a fourth fresh cycle, you'd add 60% of the remaining 6.4% chance of a BFN (.60 x .064, or 3.84%), so now your cumulative odds are greater than 97%.

A fifth fresh cycle gets you close to 99%, while a 6th puts you over 99% (which is presumably why SG's money-back quarantee covers up to 6 cycles).

(Note that your cumulative odds NEVER reach 100% -- they get closer and closer to 100, but there's always a slim chance that an infinite number of cycles would still result in a BFN.)

Love this explanation! I was always doing this math in my head when I was trying, though my odds were MUCH lower!

[Anonymous]

Anonymous wrote:18:54 again, technically every transfer is a new roll of the dice, but if you want to calculate cumulative odds of success, I believe it works like this (anyone out there who knows better feel free to correct my math!):

At SG, odds of clinical pregnancy for a single embryo transfer using DE VF are 60%.

So, say you have a fresh eSET, you have a 60% chance of pregnancy, with a 40% chance of a BFN.

If you did a second fresh cycle, you would calculate 60% times the 40% chance of a BFN (.60 x .40), which is 24%, and add that to the first cycle's 60%.

So for the two fresh cycles combined, your cumulative odds of success are 84%.

For a third fresh cycle, you'd calculate 60% of the remaining 16% chance of a BFN (.60 x .16), which is 9.6%, and add it to the 84%, so the cumulative odds of a clinical pregnancy over three cycles would be 93.6%.

For a fourth fresh cycle, you'd add 60% of the remaining 6.4% chance of a BFN (.60 x .064, or 3.84%), so now your cumulative odds are greater than 97%.

A fifth fresh cycle gets you close to 99%, while a 6th puts you over 99% (which is presumably why SG's money-back quarantee covers up to 6 cycles).

(Note that your cumulative odds NEVER reach 100% -- they get closer and closer to 100, but there's always a slim chance that an infinite number of cycles would still result in a BFN.)

This assumes that cycles are independent but they are not.

[Anonymous]

We've done 3: 2 abroad and 1 at SG. BFN for the two abroad / chemical (early miscarriage) at 6 weeks for the 1 at SG. All were CGH frozen embryos.

[Anonymous]

Anonymous wrote:We've done 3: 2 abroad and 1 at SG. BFN for the two abroad / chemical (early miscarriage) at 6 weeks for the 1 at SG. All were CGH frozen embryos.

All were CGH normal embryos?

[Anonymous]

Anonymous wrote:

Anonymous wrote:18:54 again, technically every transfer is a new roll of the dice, but if you want to calculate cumulative odds of success, I believe it works like this (anyone out there who knows better feel free to correct my math!):

At SG, odds of clinical pregnancy for a single embryo transfer using DE VF are 60%.

So, say you have a fresh eSET, you have a 60% chance of pregnancy, with a 40% chance of a BFN.

If you did a second fresh cycle, you would calculate 60% times the 40% chance of a BFN (.60 x .40), which is 24%, and add that to the first cycle's 60%.

So for the two fresh cycles combined, your cumulative odds of success are 84%.

For a third fresh cycle, you'd calculate 60% of the remaining 16% chance of a BFN (.60 x .16), which is 9.6%, and add it to the 84%, so the cumulative odds of a clinical pregnancy over three cycles would be 93.6%.

For a fourth fresh cycle, you'd add 60% of the remaining 6.4% chance of a BFN (.60 x .064, or 3.84%), so now your cumulative odds are greater than 97%.

A fifth fresh cycle gets you close to 99%, while a 6th puts you over 99% (which is presumably why SG's money-back quarantee covers up to 6 cycles).

(Note that your cumulative odds NEVER reach 100% -- they get closer and closer to 100, but there's always a slim chance that an infinite number of cycles would still result in a BFN.)

This assumes that cycles are independent but they are not.

Also assumes that recipient, egg donor, and the husband or sperm donor have no major underlying issues. I love the explanation, though - that's how it would work if everything worked reasonably well and all cycles were independent.

It worked first try for us.

[Anonymous]

Yes - all were CGH normals.

[Anonymous]

One DE cycle, resulted in ten embryos. Took three FETs though.