bad side effects with Lupron?

Anonymous
I am supposed to start Lupron soon for an IVF cycle. I have done some googling about it and have read some really scarey stuff. There's even a section on Erin Brokovich's website devoted to it . Has anyone had any experience with Lupron? What negative side effects did you have? Some of the stuff I've read is regarding intense depression, night sweats/night terrors, headaches, etc.
Anonymous
I think it really depends how long you take it. If only a week or two, you may not have much in the way of side effects. I did a 3 month course as a treatment for endometriosis and started having major hot flashes by 2-3 weeks in. Also struggled with some depression/moodiness.

On the plus side, the treatment did what it was supposed to and I was pregnant within a month of finishing treatment.
Anonymous
I had a horrible reaction to (a microdose of) Lupron. Seriously. Hot flashes, fogginess, and weird tingling feelings in my face. My RE took me off of it after two days. I used Cetrotide instead to suppress ovulation.

FWIW, though, my RE said that in his entire career he'd never seen anyone react to Lupron the way I did. To this day I don't know if it was just a coincidence or not, but I refuse to take it ever again.
Anonymous
op here: Under normal circumstances, I would NEVER take a drug with that many bad side effects to cure anything-- I would just deal with whatever illness I had. However, I just spoke with my RE's office and the nurse said this is the only prototcol-- that I must take Lupron for this cycle. Im honestly second guessing going through with the FET because this drug is scaring the pants off me.
Anonymous
I got headaches towards the end of taking Lupron, but when I added Estrogen back in they went away. Small price to pay for a possible BFP...
Anonymous
I've done Lupron twice (both times for just a week, microdoses). I didn't notice any side effects either time -- I slept restlessly a couple nights the second go-round, but not sure whether that was the Lupron or the extra chai lattes I drank.

The thing with side effects is it's often a crap shoot -- Lupron & Acctuane I took with barely a twinge, but I can't take Sudafed b/c my heart starts pounding a mile a minute.

You don't know how you're going to react until you take it.
Anonymous
OP I was on Lupron three or four times (it's all a little blurry now 3 years in the rear view mirror). I never had any significant side effects from it.
Anonymous
I have been on it a couple of times. The first time I didn't really have any side effects. The second time I had horrible, horrible headaches and was kind of moody. But nothing so severe that it was unbearable.
Anonymous
Anonymous wrote:op here: Under normal circumstances, I would NEVER take a drug with that many bad side effects to cure anything-- I would just deal with whatever illness I had. However, I just spoke with my RE's office and the nurse said this is the only prototcol-- that I must take Lupron for this cycle. Im honestly second guessing going through with the FET because this drug is scaring the pants off me.


Did they say why? There are other options for ovulation suppression, so I would question this. At a minimum, you have the right to understand why. I allowed myself to be put off with pat answers for a lot of my early IF treatments, and I really regret that now. I don't know if I would have asked to change things if I knew more, but I would have felt better about the process.

That said, I think the majority of people are fine using Lupron for fertility treatments. It's a short course, and there are options to keep dosing very minimal.
Anonymous
00:20, what e exactly is a microdose? How many units were you taking?


9:50, did you get a BFP? I assume you did a FET?

Anonymous
I was also wondering about lupron. I've heard about depression and messed up sex drive. Anyone experience that?
Anonymous
I was on Lupron for 2 weeks for an FET cycle. I did not experience depression but I put on some weight and my butts and thighs bulged out in all possible directions!
Anonymous
I am the 9:06 PP again. Forgot to mention about microdose lupron in a fresh IVF cycle. I used to cry for no reason. I am not sure if lupron did that or continuous IVF failures.
Anonymous
9:06, thanks for input. How much was your dosage?
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