How many donor egg transfers until you had success or called it quits?

[Anonymous]

Your husband needs to stop being a baby and get the fragmentation test done. Are you using a proven donor? My SG RE recommended that we use one, for frozen shared risk. We got 2 blasts out of 7 eggs. The first transfer didn’t work but the next one did.

[Anonymous]

One and done! (thankfully quick because I was 48 when implanted... easy pregnancy too)

[Anonymous]

OP here - we did use a proven donor and we did the 1:2 donor egg program so another couple received 1/2 of the eggs. Found out today in a follow-up appointment that the other couple is pregnant with the same donor egg lot. So it seems to be an issue with me, the sperm or just really bad luck. Since I don’t have time to run more tests on me and postpone the FET for 2+ months (we’re moving to Austria in early July) my doctor recommended we throw everything at this last transfer and do Lupron (in case I have hidden endometriosis), antibiotics, blood thinner, and steroids. If this last embryo doesn’t take then we can do more testing, including a dna fragmentation test on the sperm in case we decide to give it another go using a fertility clinic in the Czech Republic. Austria doesn’t allow donor eggs.

Doing the Lupron injections will delay the FET by a month (and per the doctor it’ll make me feel like I’m going through menopause which doesn’t sound fun) so I have to decide whether to do the Lupron or just the blood thinner, antibiotics and steroids (which won’t delay the FET). Thanks for the replies so far and would also love to hear if this protocol has worked for anyone after FET failures. Or if anyone had hidden endometriosis despite no prior indications. Thanks!

[Anonymous]

Anonymous wrote:We purchased a frozen lot (8 eggs) with a guarantee of two high quality blast. We got exactly two. First transfer ended in an early MC and I'm 28 weeks with the second. I encourage you to transfer the lower quality after you do dna testing and an immune profile, if you haven't already. Most good doctors and geneticists will readily tell you that grading is a tool that's helpful, but often not accurate. It's not uncommon for the lower grades to end in healthy babies. Good luck! I'm sorry it's been such a long road for you, it's rough.

This is so true. My second child is from my own frozen eggs, and was a 4CC blast. Some clinics wouldn't even keep blasts that poorly graded, so I'm very grateful that mine did and that they urged me to give it a shot.

[Anonymous]

Anonymous wrote:OP here - we did use a proven donor and we did the 1:2 donor egg program so another couple received 1/2 of the eggs. Found out today in a follow-up appointment that the other couple is pregnant with the same donor egg lot. So it seems to be an issue with me, the sperm or just really bad luck. Since I don’t have time to run more tests on me and postpone the FET for 2+ months (we’re moving to Austria in early July) my doctor recommended we throw everything at this last transfer and do Lupron (in case I have hidden endometriosis), antibiotics, blood thinner, and steroids. If this last embryo doesn’t take then we can do more testing, including a dna fragmentation test on the sperm in case we decide to give it another go using a fertility clinic in the Czech Republic. Austria doesn’t allow donor eggs.

Doing the Lupron injections will delay the FET by a month (and per the doctor it’ll make me feel like I’m going through menopause which doesn’t sound fun) so I have to decide whether to do the Lupron or just the blood thinner, antibiotics and steroids (which won’t delay the FET). Thanks for the replies so far and would also love to hear if this protocol has worked for anyone after FET failures. Or if anyone had hidden endometriosis despite no prior indications. Thanks!

OP I am in a similar situation. Have done 2 DE transfers, neither stuck. I have one DE blast left. I wish I would have PGS tested them.

My DH has had the frag test and he has high fragmentation. Well, what’s the solution? Use donor sperm - which we really don’t want to do. Trying to improve his frag level could take a year or more. Time we don’t have.

Definitely take the Lupron. I know 3 people who have had success with DE despite endometriosis or adenomyosis. The Lupron seemed to be the key. My doctor won’t just give me Lupron. He wants me to test for endometriosis. Yet another delay in a miserable slog of delays and heartache.

[Anonymous]

Anonymous wrote:

OP I am in a similar situation. Have done 2 DE transfers, neither stuck. I have one DE blast left. I wish I would have PGS tested them.

My DH has had the frag test and he has high fragmentation. Well, what’s the solution? Use donor sperm - which we really don’t want to do. Trying to improve his frag level could take a year or more. Time we don’t have.

Definitely take the Lupron. I know 3 people who have had success with DE despite endometriosis or adenomyosis. The Lupron seemed to be the key. My doctor won’t just give me Lupron. He wants me to test for endometriosis. Yet another delay in a miserable slog of delays and heartache.

I read this and thought what the hell about already using donor eggs but not donor sperm. He's OK with you not being the biological mother, but he must be the biological father? I think it comes down to whether you want to eventually have children and worthwhile having that odds of success talk with your RE. I don't think it's fair for the woman to go through repeated treatments with donor eggs when testing shows sperm issues, but the man is completely inflexible about donor sperm.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

OP I am in a similar situation. Have done 2 DE transfers, neither stuck. I have one DE blast left. I wish I would have PGS tested them.

My DH has had the frag test and he has high fragmentation. Well, what’s the solution? Use donor sperm - which we really don’t want to do. Trying to improve his frag level could take a year or more. Time we don’t have.

Definitely take the Lupron. I know 3 people who have had success with DE despite endometriosis or adenomyosis. The Lupron seemed to be the key. My doctor won’t just give me Lupron. He wants me to test for endometriosis. Yet another delay in a miserable slog of delays and heartache.

I read this and thought what the hell about already using donor eggs but not donor sperm. He's OK with you not being the biological mother, but he must be the biological father? I think it comes down to whether you want to eventually have children and worthwhile having that odds of success talk with your RE. I don't think it's fair for the woman to go through repeated treatments with donor eggs when testing shows sperm issues, but the man is completely inflexible about donor sperm.

My DH and I both agree we don’t want to use donor sperm. We have an older child and hope that they will at least be a half bio-sibling with the new baby. That’s why.

[Anonymous]

Anonymous wrote:

Anonymous wrote:We purchased a frozen lot (8 eggs) with a guarantee of two high quality blast. We got exactly two. First transfer ended in an early MC and I'm 28 weeks with the second. I encourage you to transfer the lower quality after you do dna testing and an immune profile, if you haven't already. Most good doctors and geneticists will readily tell you that grading is a tool that's helpful, but often not accurate. It's not uncommon for the lower grades to end in healthy babies. Good luck! I'm sorry it's been such a long road for you, it's rough.

This is so true. My second child is from my own frozen eggs, and was a 4CC blast. Some clinics wouldn't even keep blasts that poorly graded, so I'm very grateful that mine did and that they urged me to give it a shot.

My only live birth was from a day five 2BB. It was the last sad ragged little embryo I had. I have transferred 5AAs only to miscarry. My little 2BB stuck around and is my only child.

He’s still a low-key, mellow kind of guy, btw. 😉

[Anonymous]

On the third try. The grading is meaningless without PGD. I had all tested and then out of the normals, Dr transferred the ones with best morphology. Third one stuck luckily for me.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

OP I am in a similar situation. Have done 2 DE transfers, neither stuck. I have one DE blast left. I wish I would have PGS tested them.

My DH has had the frag test and he has high fragmentation. Well, what’s the solution? Use donor sperm - which we really don’t want to do. Trying to improve his frag level could take a year or more. Time we don’t have.

Definitely take the Lupron. I know 3 people who have had success with DE despite endometriosis or adenomyosis. The Lupron seemed to be the key. My doctor won’t just give me Lupron. He wants me to test for endometriosis. Yet another delay in a miserable slog of delays and heartache.

I read this and thought what the hell about already using donor eggs but not donor sperm. He's OK with you not being the biological mother, but he must be the biological father? I think it comes down to whether you want to eventually have children and worthwhile having that odds of success talk with your RE. I don't think it's fair for the woman to go through repeated treatments with donor eggs when testing shows sperm issues, but the man is completely inflexible about donor sperm.

My DH and I both agree we don’t want to use donor sperm. We have an older child and hope that they will at least be a half bio-sibling with the new baby. That’s why.

+1

I also would draw the line at double donor. I want my kid to be biologically related to *someone* in the family, or we might as well just adopt. Or not have kids. I know people who did double donor (or donor embryo), and it works for them. But it's not for us.