Do PGS or not?

[Anonymous]

Anonymous wrote:This is an interesting thread for me as I noticed that PGS testing is getting to be a norm now. Two years ago at age 35, I did a fresh cycle, and my doctor did not even bring up PGS testing and I didn't even know what it was. I conceived my daughter successfully, and have 6 frozen embryos. This time around for FET, I asked him if I should do it and he acknowledged that almost everyone is doing it, but he didn't see a reason for me to do it. I didn't, but I always wonder if I should.

I am similar. I did fresh IVF in 2011, and they didnt even mention it. When I went to do FET in 2014, we thawed my frozen embryos and PGD tested them. Now I am doing another fresh cycle, and it's basically part of the protocol - for example CCRM doesn't even do IVF without it now.

[Anonymous]

A fairly prominent RE I spoke with alluded to another well known clinic boosting its SART data by doing embryo banking then PGS testing all. If you have the time and the money to go that way, it probably wouldn't hurt. As I only produced 5 eggs and three made it to blast, he suggested, at my age, to transfer all. Currently BFP with a singleton.

[Anonymous]

Anonymous wrote:A fairly prominent RE I spoke with alluded to another well known clinic boosting its SART data by doing embryo banking then PGS testing all. If you have the time and the money to go that way, it probably wouldn't hurt. As I only produced 5 eggs and three made it to blast, he suggested, at my age, to transfer all. Currently BFP with a singleton.

wait, you transferred 3 blasts at one time?

[Anonymous]

Not the PP but that is the recommendation for older women
https://www.asrm.org/uploadedFiles/ASRM_Content/News_and_Publications/Practice_Guidelines/Guidelines_and_Minimum_Standards/Guidelines_on_number_of_embryos.pdf

[Anonymous]

With a pretty heavy immune protocol, I'd do the PGS so if it doesn't work you can make tweaks to the immune protocol more directly.

I'm on a similar immune protocol and pregnant from TI. I have all the worries that the pregnancy will be lost for genetic reasons and I'll have gone through all these shots and drugs for nothing. If I could eliminate that worry from my list, I would. I am 36.

[Anonymous]

Anonymous wrote:With a pretty heavy immune protocol, I'd do the PGS so if it doesn't work you can make tweaks to the immune protocol more directly.

I'm on a similar immune protocol and pregnant from TI. I have all the worries that the pregnancy will be lost for genetic reasons and I'll have gone through all these shots and drugs for nothing. If I could eliminate that worry from my list, I would. I am 36.

You could have eliminated it by doing IVF, but you chose to do smth less invasive - TI. Further, PGS does not guard against miscarrying a normal embryo, unfortunately.

[Anonymous]

Update:

I've decided to let the embryos grow to day 5. If it looks like we have a lot that will make it , we will PGS and freeze.

If we don't have a lot that looks like they will make it (2-3 or less) I'm going to fresh transfer.

I'll prepare for the transfer just in case.

[Anonymous]

Anonymous wrote:Update:

I've decided to let the embryos grow to day 5. If it looks like we have a lot that will make it , we will PGS and freeze.

If we don't have a lot that looks like they will make it (2-3 or less) I'm going to fresh transfer.

I'll prepare for the transfer just in case.

Since you are getting two attempts counted against you anyway, why not fresh transfer a pair on day 5 and send anything else to PGS testing at the same time?