OP: Total cholesterol 188, HDL 71, LDL 112. I have high LipA which is 100% genetic as you likely know. The CT coronary calcium score was 14. My cardiologist initially did not suggest a statin but changed her mind when I got the calcium score. I run 3 - 4x/week, eat mostly vegetarian, almost no fried food (rarely eat out), and eat very little sugar. I'm not sure there's much more I can do diet and exercise-wise. |
I am that poster and thanks for mentioning this! I had wondered if dramatic weight loss might bring it down. My BMI is 27. I won’t see my PCP again until next year but have an appointment coming up with a cardiologist. Will ask them about it. Thanks again! |
This is a recent article in a preeminent medical journal that compares statins to hrt in women for prevention of heart disease. https://pubmed.ncbi.nlm.nih.gov/35594469/ |
| ^ oh and NP not the one you were responding to. Not a medical professional |
| With elevated lp(a) you want to keep LDL as low as you can. 10 mg is a very low dose, you will probably not have side effects. But if you do you can cut the pill and try 5 or even 2.5. |
Take along a prior authorization form for them to fill out. Even without weight loss, it’s Rx for cholesterol control. But the bmi will help get it approved. |
Thanks. I am OP, not the Wegovy poster FYI. I'm very thin, with a family history of breast cancer, so neither GLPs nor HRT are a good solution for me. Hopefully the 10mg won't cause side effects. |
| I am a 58 year old female and have been taking 20mg Crestor daily for 4 years. No side effects for me. |
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Many people have no issues. And they definitely work at reducing cardiovascular issues. I switched to a statin from niacin bc studies of niacin didn't show same benefit even though it lowers cholesterol. I haven't had issues with statins.
Muscle soreness can be a side effect. If you do have that, it would typically show up in a couple weeks and you shouldn't continue statins if you have that side effect (its a sign of potentially significant problems). Talk to a doc, of course, but you can often test to see if its the statins if it's not clear, by stopping and restarting to see if there is a clear connection. My father an aunt both have that side effect. There is another class of drugs (PCSK9 inhibitors) that work very well, too, but they're signifiantly more expensive (i.e., insurance won't cover it unless statins really don't work) and are currently only offered as injectibles. I think an oral version is on its way to market. |
If OP already has a positive calcium score, LDL needs to be much lower than 112. It should probably be around 70. Recent research on HDL shows it's not necessarily so protective with increased LDL levels (or lp(a). If she didn't have a positive calcium score then yes, 112 may be ok to monitor and try to get lower with diet and exercise. |
| OP, I started 5 mg of Crestor and got my LDL down from 100 to 75 -- and started eating a bit less restrictively too. No side effects. |
+1 and I think with elevated Lp(a) they want ldl below 70. |
| I'm on 80 MG. I don't think I have any side effects. I have brain fog but I always thought that was just getting old/menopause. |
| If you are pre-diabetic or close to, statins can push you into full diabetes. It's documented and it happened to my mother. |
My mom and husband experienced memory issues after starting statins. These are not friendly medications. It’s better to implement major lifestyle improvements than to take them. Husband also experienced big problems with his temperament during his time on statin, anger and depression |