FRAT testing?

[Anonymous]

Has anyone pursued this for their child? My DS6 has ADHD and a severe language disorder and possibly also ASD. If you are in the DC area, can you share the name of a provider who helped. Thanks in advance!

[Anonymous]

Go to fratnow.com and order the test. Bring the sheet to your family doctor for them to sign.
You should also email your doctor the studies behind it.

[Anonymous]

Anonymous wrote:Go to fratnow.com and order the test. Bring the sheet to your family doctor for them to sign.
You should also email your doctor the studies behind it.

Is it expensive?

[Anonymous]

Anonymous wrote:

Anonymous wrote:Go to fratnow.com and order the test. Bring the sheet to your family doctor for them to sign.
You should also email your doctor the studies behind it.

Is it expensive?

Its around 400 dollars. You also have to see if your doctors office will do the blood draw. If not you will have to find an independent draw through a nurse or phlebotomist.

[Anonymous]

DP - I would like to get this done but our ped does not do blood draws. Will just fill out a form you take to Quest or Labcorp depending on your insurance. How do you find an independent phlebotomist

[Anonymous]

Anonymous wrote:DP - I would like to get this done but our ped does not do blood draws. Will just fill out a form you take to Quest or Labcorp depending on your insurance. How do you find an independent phlebotomist

You should check if either of those do independent blood draws.

If not, Google for independent blood draw or mobile phlebotomist or ask your doctors office for a recommendation

[Anonymous]

The test was a few hundred dollars and we have not tried to submit it to insurance yet. But the medication is covered and we have had such positive effects that it was worth it. Especially given the thousands we put into therapies and co-pays at places that did nothing to help over the years.

[Anonymous]

Is the test definitive?

[Anonymous]

Anonymous wrote:The test was a few hundred dollars and we have not tried to submit it to insurance yet. But the medication is covered and we have had such positive effects that it was worth it. Especially given the thousands we put into therapies and co-pays at places that did nothing to help over the years.

NP here. Can you tell us what benefits you’ve seen? I have a 17 year old daughter (ASD/ADHD) who cannot tolerate psych meds and we too have spent thousands trying to help her with depression, anxiety and emotional dysregulation. Several reputable medical professionals have suggested folate malabsorption.

[Anonymous]

Anonymous wrote:

Anonymous wrote:The test was a few hundred dollars and we have not tried to submit it to insurance yet. But the medication is covered and we have had such positive effects that it was worth it. Especially given the thousands we put into therapies and co-pays at places that did nothing to help over the years.

NP here. Can you tell us what benefits you’ve seen? I have a 17 year old daughter (ASD/ADHD) who cannot tolerate psych meds and we too have spent thousands trying to help her with depression, anxiety and emotional dysregulation. Several reputable medical professionals have suggested folate malabsorption.

I have posted previously about my son who was put on a very high dose of Sertraline beginning in elementary school. His anxiety was debilitating. We later found that he had low iron and his hemoglobin was on the very low side of normal. After giving iron supplements, we were finally able to (slowly) take him off Sertraline for good. That was maybe 3 years ago and he continued to do well.

Recently we had the FRAT test and he turned out to be positive for the folate blocking antibodies, too. Since beginning the leucovorin, have seen subtle improvements in his social engagement, mood and conversation.

I will warn you that they warned us - one of the ways you know leucovorin is working is that you will see stronger emotions at first. This means both positive and negative emotions. You are supposed to start with a very low does and go slowly in increasing the dose.

Also you should test for iron anemia full panel, methylmalonic acid and b12 and homocysteine and you should also do a genetic test for mthfr mutations as there are some that can lead to folate problems. Many many people have mthfr mutations, but there are 2 very specific ones that actually cause problems.

[Anonymous]

Anonymous wrote:Is the test definitive?

Only a lumbar puncture is definitive for the amout of folate in fhe spinal fluid.
The frat test is definitive for the number and type of antibodies.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:The test was a few hundred dollars and we have not tried to submit it to insurance yet. But the medication is covered and we have had such positive effects that it was worth it. Especially given the thousands we put into therapies and co-pays at places that did nothing to help over the years.

NP here. Can you tell us what benefits you’ve seen? I have a 17 year old daughter (ASD/ADHD) who cannot tolerate psych meds and we too have spent thousands trying to help her with depression, anxiety and emotional dysregulation. Several reputable medical professionals have suggested folate malabsorption.

I have posted previously about my son who was put on a very high dose of Sertraline beginning in elementary school. His anxiety was debilitating. We later found that he had low iron and his hemoglobin was on the very low side of normal. After giving iron supplements, we were finally able to (slowly) take him off Sertraline for good. That was maybe 3 years ago and he continued to do well.

Recently we had the FRAT test and he turned out to be positive for the folate blocking antibodies, too. Since beginning the leucovorin, have seen subtle improvements in his social engagement, mood and conversation.

I will warn you that they warned us - one of the ways you know leucovorin is working is that you will see stronger emotions at first. This means both positive and negative emotions. You are supposed to start with a very low does and go slowly in increasing the dose.

Also you should test for iron anemia full panel, methylmalonic acid and b12 and homocysteine and you should also do a genetic test for mthfr mutations as there are some that can lead to folate problems. Many many people have mthfr mutations, but there are 2 very specific ones that actually cause problems.

Who did this testing for you and told you want to take? Mine does have a MTHFR mutation that showed up in Genesight testing

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:The test was a few hundred dollars and we have not tried to submit it to insurance yet. But the medication is covered and we have had such positive effects that it was worth it. Especially given the thousands we put into therapies and co-pays at places that did nothing to help over the years.

NP here. Can you tell us what benefits you’ve seen? I have a 17 year old daughter (ASD/ADHD) who cannot tolerate psych meds and we too have spent thousands trying to help her with depression, anxiety and emotional dysregulation. Several reputable medical professionals have suggested folate malabsorption.

I have posted previously about my son who was put on a very high dose of Sertraline beginning in elementary school. His anxiety was debilitating. We later found that he had low iron and his hemoglobin was on the very low side of normal. After giving iron supplements, we were finally able to (slowly) take him off Sertraline for good. That was maybe 3 years ago and he continued to do well.

Recently we had the FRAT test and he turned out to be positive for the folate blocking antibodies, too. Since beginning the leucovorin, have seen subtle improvements in his social engagement, mood and conversation.

I will warn you that they warned us - one of the ways you know leucovorin is working is that you will see stronger emotions at first. This means both positive and negative emotions. You are supposed to start with a very low does and go slowly in increasing the dose.

Also you should test for iron anemia full panel, methylmalonic acid and b12 and homocysteine and you should also do a genetic test for mthfr mutations as there are some that can lead to folate problems. Many many people have mthfr mutations, but there are 2 very specific ones that actually cause problems.

Who did this testing for you and told you want to take? Mine does have a MTHFR mutation that showed up in Genesight testing

Again, it doesn't matter if they have a mthfr mutation. You can have mthfr mutations and not have any problems. What matters is the specific mutations that you have. Take the results of your genesis test and upload them into chatgpt. Tell it to read the results for any possible folate deficiency. It will probably tell you if you need to be concerned or not. If you have specific mutations that do effect folate levels you take methylated folate . Ask the Ai to tell you how much you need based on bodyweight etc.

[Anonymous]

Our ped said he wouldn't do it because there is not enough evidence to support the rest or the treatment. Can anyone recommend a specific provider who might let us run this down?

[Anonymous]

Anonymous wrote:Our ped said he wouldn't do it because there is not enough evidence to support the rest or the treatment. Can anyone recommend a specific provider who might let us run this down?

She wouldn't sign off on the frat test?