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[quote=Anonymous][quote=Anonymous][quote=Anonymous]The test was a few hundred dollars and we have not tried to submit it to insurance yet. But the medication is covered and we have had such positive effects that it was worth it. Especially given the thousands we put into therapies and co-pays at places that did nothing to help over the years.[/quote]

NP here. Can you tell us what benefits you’ve seen? I have a 17 year old daughter (ASD/ADHD) who cannot tolerate psych meds and we too have spent thousands trying to help her with depression, anxiety and emotional dysregulation. Several reputable medical professionals have suggested folate malabsorption.[/quote]

I have posted previously about my son who was put on a very high dose of Sertraline beginning in elementary school. His anxiety was debilitating. We later found that he had low iron and his hemoglobin was on the very low side of normal. After giving iron supplements,  we were finally able to (slowly) take him off Sertraline for good. That was maybe 3 years ago and he continued to do well.

Recently we had the FRAT test and he turned out to be positive for the folate blocking antibodies,  too. Since beginning the leucovorin,  have seen subtle improvements in his social engagement,  mood and conversation.

I will warn you that they warned us - one of the ways you know leucovorin is working is that you will see stronger emotions at first. This means both positive and negative emotions. You are supposed to start with a very low does and go slowly in increasing the dose.

Also you should test for iron anemia full panel, methylmalonic acid and b12 and homocysteine and you should also do a genetic test for mthfr mutations as there are some that can lead to folate problems.  Many many people have mthfr mutations, but there are 2 very specific ones that actually cause problems.

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