MTHFR gene and mental illness
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Anonymous
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A sibling has bipolar disorder and has had periods of psychosis that require hospitalization.
Her counselor recently encouraged her to take a genetic test for the MTHFR variant. Apparently people with this variant are more prone to psychiatric disorders, including bipolar and periods of psychosis. My sister just got her results and has double helix mutation. They now want her on a pretty high dose of supplements to counteract it and believe it will immensely help her. I found one article via Journal below, where this research is validated. Wanted to see if anyone else has heard of it or had experience with doing high-dose supplements to make up for this variant and having a positive impact on mental health? It's interesting. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433753/ |
Anonymous
| really? I am MTFHR positive, which we found as part of standard fertility testing. I can't remember the variation, it's the lesser severe |
Anonymous
| Sorry, I have nothing useful to add but my imagination came up with a different long form for MTHFR than I’m sure what it really stands for, and it gave me a chuckle. |
Anonymous
| Any practitioner treating a genetic or mental disorder with nutritional supplements is a whacko. That’s not standard of care in any field of medicine. |
Anonymous
You do realize what MTHFR does to the body? |
Anonymous
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Your citation is to a study regarding the prevalence of the gene mutation in populations with mental illness. I don't see anything in there about supplements that would somehow "counteract it." What supplements and who recommended them and why?
I have bipolar disorder and am also working on a book about treatment for mental illness and I have no idea what you are talking about. Sounds very scammy -- as many treatments involving "supplements are -- but I'm ready to read what you have to write about it. |
Anonymous
Not PP, but I "realize what MTHFR does to the body" and I'm not sure how "what MTHFR does to the body" validates the use of supplements to treat serious mental illness. |
Anonymous
Why is it so hard for people to consider that there are things that the body needs that don't come from a pharmaceutical company? |
Anonymous
lol same here! Whoever got that acronym to stick within the scientific community has a pretty twisted sense of humor. And yes I know it’s an acronym for a specific gene sequence. This should be the name of a kind of cancer. As in “I got that MTHFR cancer!!” |
Anonymous
This is false. Studies have shown an association between MTHFR and vitamin B12 deficiency. |
Anonymous
That proves literally nothing. Studies have shown a relationship between being on DCUM and being a know it all. So??????? |
Anonymous
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OP here. My sibling has been on medicine for 15 years. 100 percent compliant. Her psychiatrist is recommending these supplements in addition to the normal meds they are on.
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Anonymous
| What supplements are they recommending? |
Anonymous
| I never heard of this connection. I heard it was related to blood clots. |
Anonymous
| Just curious at to why your sister has frequent psychotic episodes that require hospitalization if she is 100% compliant on her meds? |