Looking at all the posts from people frustrated by their weight, I wanted to share my experience with Mounjaro, the lastest in a series of medications initially developed to treat type 2 diabetes (earlier meds include Ozempic and Wegovy).
I am 53 and, as of the beginning of July, I was overweight. Not obese– I didn't look "fat"– but at 5' 2" and just over 150lbs, the curves were gone, my waist was thicker, and I was generally pretty miserable about how I looked. My diet was already healthy and I already got plenty of exercise, so although I was unhappy, I figured it was just normal aging and I had to accept it. Then I had bloodwork done and discovered I was prediabetic– only just, but prediabetic– and my blood pressure was also high. My doctor suggested Mounjaro, which is used off-label for weight loss, pre-diabetes, and high BP. To my surprise, my insurance (Carefirst) covered it completely, so I thought it was worth a try. 3 months later, I am thirty pounds lighter, my HbA1c levels are normal, and BP is normal. I have not been this slender for at least two decades. It's almost unbelievable. I have had to buy new clothes. Mounjaro is taken as a weekly self-administered injection. Normally they start you at 2.5 mg for a month, then go up in 2.5mg increments each month. I went from 2.5 in July to 5mg in August. In September I went to 7.5 for a week, but the side effects got a lot worse, and i went back to 2.5mg (on which I continued to lose weight!) Basically, Mounjaro reduces your appetite and, when you eat, makes you feel full faster. It also does various things to your insulin and glycemic response, but what you notice is just... you're not very hungry most of the time. The thought of big, fatty meals makes you feel yucky, and when you eat, even if it's something you like, you're full after just a small portion. Most common negative side effects: nausea, dry mouth, constipation. Everyone is different, but for me, side effects were minimal at 2.5 (very mild nausea just once, minor dry mouth), noticeable at 5 (somewhat more nausea, dry mouth got annoying, and had to take colace), and really unpleasant at 7.5. (All of the above, but more). Now I am back at 2.5 and the side effects are minimal again. These meds are new, so no one really knows if they will eventually cause a sort of "metabolic reset" and you can go off them and stay healthy and slim, or if you inevitably revert back when off them. Best guess is that people may need to consider them lifetime drugs, just like blood pressure meds. However: I plan to start alternating weeks with the 2.5mg, one week on, one week off, because I am at a point where I don't want to lose more weight. I just want to stay where I am, which is now right smack in the middle of "normal" on the BMI charts. Anyway: these meds are not for everyone. Some people can't tolerate the side effects, and some have medical conditions or take other meds incompatible with these. And they are new, so although they appear to be quite safe so far, there are only a few years of data. (Of course, being overweight, prediabetic and hypertensive also carries serious health risks). But I wanted to share this for those of you who feel completely stuck. This medication works. It really feels almost like magic, and it is transforming how doctors think of obesity. So: google the studies on it; consult your doctor; join one of the Mounjaro facebook groups to get more stories from others. It might be something that will work for you. Best wishes, everyone, and happy to answer any questions if I can. |
No such thing as Miracle weight loss. Is this the one associated with thyroid Illness? At any rate way too fast to lose weight |
PP, maybe do some actual research before responding? |
Mounjaro is one of the new semaglutide drugs, along with Ozempic and Wegovy and Saxenda that have been a game changer. For those that have struggled for years to lose weight, this drug has been a “miracle.” It’s not a magic bullet, but it does really work for so many. |
Thanks for your post! My Dr mentioned this in passing but I had forgotten the name of the drug. Off to Google now! |
I’m on the 15mg dose, it doesn’t work nearly as good for me as Wegovy but it definitely cuts the food noise in my head. This medication seems to just cut cravings completely. Like for everything. I haven’t had any side affects at all. I lost over 100lbs on Wegovy. As someone who has struggled with their weight for many years, I just hate to hear about all the folks who want to take it just to lose 10lbs, or those with a BMI of 26 and below on it. But I know I have ignore that noise as well. |
^Side effects |
Why do you hate to hear about a less overweight pre-diabetic taking it? Weird hang up. |
I feel the same. My goal weight is higher than OP's starting weight! I've been on Ozempic since mid-July, am the same height as the OP (5'2") but 40 lbs heavier at 195 lbs. I've lost no weight. It hasn't been "magic" for me and hasn't made me feel any different at all. It's all very frustrating. |
I’m talking about the women, men, and very young looking girls specifically, all over TikTok taking Mournjaro to lose 10lbs to control their appetite, treating this medication like it’s nothing. Not reading up on it, ending up in the ER because they skipped doses trying to get to the highest dose for appetite suppression. They are getting it from telehealth providers by straight up lying about their stats. The medication was not studied on that demographic for WEIGHT LOSS. If and when that demographic starts to report adverse effects, it may cause issue for ELI LILY to get FDA approval for Mournjaro for weight loss. Folks, including me are taking this medication off label for weight loss, what you’re describing would be people taking it for it’s FDA approved use, which I could completely understand. I am very hopeful about this medication, will probably need to take it or something like it for life. I need it to stay on the market and not be ruined by vanity users. Eli Lily has already changed the requirements of the coupon because they are suspecting abuse and have concerns about FDA approval. They are trying to get it fast tracked now. |
Thanks for your post! I am in almost exactly the same situation -- 53, overweight (not obese), pre-diabetic (but just barely), plus high-ish bad cholestorel. I'm working on my diet and reassessing in a couple of months, but it will be good to have this information in my back pocket when I go back to the doctor. |
Unfortunately I think abuse is a forgone conclusion for these meds. But obesity is a serious enough problem that I think they’ll stay accessible to those who truly need them. I’m surprised OP was allowed to take them being barely overweight actually. I admit that I’d be curious to try meds to lose 15 lbs but I know that’s not the purpose. And I would not want to be on them for life, and who knows what the rebound would be. But I am very happy they exist for people with obesity who need them! |
Very similar stats. I am 52, 5’2. I had been holding steady at 173, but then gained up to 178. Since starting on Mournjaro, I really haven’t lost a lot of weight but it definitely helps me maintain what I lost on Wegovy, so I’m not totally frustrated. My goal weight is 160. When I can get to 160 and maintain for 6 months, going to have my extra skin removed, which would probably be an additional 6-8lbs. |
This is OP. I definitely do not think anyone should use this medication to go from a healthy weight to 10 pounds lighter. The medication has side effects that can be quite unpleasant for some who take it, and a lot of long-term unknowns. It’s not something anyone should just mess around with.
For people who are obese, have type two diabetes, or are overweight and have one or more accompanying weight-related health problems (such as Pre-diabetes or hypertension), I think it’s a different story. In those cases it’s an issue of comparative risks: The medication carries risks, but so do the underlying health conditions, and only each individual and their doctor can decide whether the risks of the medication outweigh the risks of the existing health problems, or not. For me, now that I am back at a healthy weight and i’ve gotten the blood sugar and blood pressure under control, My plan is to stay at the lowest possible dose, and experiment with skipping weeks. I am not looking to get super thin, just to stay healthy. But I won’t lie, I am thrilled by the weight loss, And this family of medication does appear to be a game changer for the treatment of both diabetes and other obesity and weight related health issues. |
But what happens when you stop taking it? Let us know. |