How worried to be about birth defects with advanced maternal age?

[Anonymous]

Anonymous wrote:

Anonymous wrote:Be concerned and monitor closely don't listen to the people on here they think they can defy science

this isn't defying science - the women of yesteryear who had 12+ children were all having children past 35. you have no idea WHAT you are talking about.

It is important to address the issue of misinformation and emphasize the potential dangers associated with women having children past the age of 35. Here is a strong refutation, supported by statistics, to discourage the spread of misinformation:

It is imperative to stop spreading misinformation and instead rely on scientific evidence and expert advice when discussing matters of reproductive health. Dismissing the risks associated with advanced maternal age is not only irresponsible but also potentially harmful. Allow me to provide you with compelling statistics that highlight the dangers of women having children past the age of 35:

1. Increased risk of chromosomal abnormalities: Scientific research consistently shows that the risk of chromosomal abnormalities, such as Down syndrome, significantly increases with maternal age. According to the American College of Obstetricians and Gynecologists (ACOG), the risk of Down syndrome at age 35 is about 1 in 200, while at age 40, it becomes approximately 1 in 100, and by age 45, it rises to about 1 in 30. These statistics clearly demonstrate the substantial escalation in risk as women age.

2. Higher risk of pregnancy complications: Advanced maternal age is associated with a higher likelihood of experiencing various pregnancy complications. According to a study published in the Journal of Obstetrics and Gynaecology Canada, women aged 35 and older have an increased risk of gestational diabetes, preeclampsia, placenta previa, and premature birth. These complications can pose serious health risks to both the mother and the baby.

3. Decreased fertility and increased miscarriage risk: Women in their late 30s and beyond experience a decline in fertility. The ACOG reports that after the age of 35, a woman's chances of getting pregnant each month decrease significantly. Additionally, the risk of miscarriage also rises with advancing maternal age. According to a study published in the journal Fertility and Sterility, women aged 35-39 have a 20% chance of miscarriage, which increases to 35% for women aged 40-44.

4. Increased likelihood of pregnancy interventions: Advanced maternal age often necessitates additional medical interventions during pregnancy. Women over 35 are more likely to require assisted reproductive technologies, such as in vitro fertilization (IVF), to achieve pregnancy. These interventions can be physically and emotionally taxing, as well as financially burdensome.

By spreading misinformation, you are disregarding the well-established scientific knowledge and putting women and their potential children at risk. It is crucial to prioritize evidence-based information and encourage individuals to consult healthcare professionals who can provide accurate guidance based on each person's unique circumstances.

I implore you to stop spreading dangerous misinformation and instead advocate for responsible and informed discussions that prioritize the health and well-being of women and their children. Science offers us invaluable insights that should guide our decisions and actions for the betterment of society as a whole.

[Anonymous]

Well, on the other side of things, I have a child with significant SN and I had DC when I was only 26. We went on to have a few more children after DC and my last at 37 and DC is our only child with SN. I have friends who have 3 children all with SN. There's no way to know beforehand, you get what you get.

[Anonymous]

Every time you have a baby it’s a gamble. I’m on my fourth and am now 37. You truly never know what can happen.

[Anonymous]

I had mine at 35 and 38. You do the blood test at 8-10 weeks and then the scan at 11-13 and it gives you an idea. You can’t screen for autism which is a big deal imo. Sounds like a third isn’t for you.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Be concerned and monitor closely don't listen to the people on here they think they can defy science

this isn't defying science - the women of yesteryear who had 12+ children were all having children past 35. you have no idea WHAT you are talking about.

It is important to address the issue of misinformation and emphasize the potential dangers associated with women having children past the age of 35. Here is a strong refutation, supported by statistics, to discourage the spread of misinformation:

It is imperative to stop spreading misinformation and instead rely on scientific evidence and expert advice when discussing matters of reproductive health. Dismissing the risks associated with advanced maternal age is not only irresponsible but also potentially harmful. Allow me to provide you with compelling statistics that highlight the dangers of women having children past the age of 35:

1. Increased risk of chromosomal abnormalities: Scientific research consistently shows that the risk of chromosomal abnormalities, such as Down syndrome, significantly increases with maternal age. According to the American College of Obstetricians and Gynecologists (ACOG), the risk of Down syndrome at age 35 is about 1 in 200, while at age 40, it becomes approximately 1 in 100, and by age 45, it rises to about 1 in 30. These statistics clearly demonstrate the substantial escalation in risk as women age.

2. Higher risk of pregnancy complications: Advanced maternal age is associated with a higher likelihood of experiencing various pregnancy complications. According to a study published in the Journal of Obstetrics and Gynaecology Canada, women aged 35 and older have an increased risk of gestational diabetes, preeclampsia, placenta previa, and premature birth. These complications can pose serious health risks to both the mother and the baby.

3. Decreased fertility and increased miscarriage risk: Women in their late 30s and beyond experience a decline in fertility. The ACOG reports that after the age of 35, a woman's chances of getting pregnant each month decrease significantly. Additionally, the risk of miscarriage also rises with advancing maternal age. According to a study published in the journal Fertility and Sterility, women aged 35-39 have a 20% chance of miscarriage, which increases to 35% for women aged 40-44.

4. Increased likelihood of pregnancy interventions: Advanced maternal age often necessitates additional medical interventions during pregnancy. Women over 35 are more likely to require assisted reproductive technologies, such as in vitro fertilization (IVF), to achieve pregnancy. These interventions can be physically and emotionally taxing, as well as financially burdensome.

By spreading misinformation, you are disregarding the well-established scientific knowledge and putting women and their potential children at risk. It is crucial to prioritize evidence-based information and encourage individuals to consult healthcare professionals who can provide accurate guidance based on each person's unique circumstances.

I implore you to stop spreading dangerous misinformation and instead advocate for responsible and informed discussions that prioritize the health and well-being of women and their children. Science offers us invaluable insights that should guide our decisions and actions for the betterment of society as a whole.

nothing you said contradicts or adds insight to what i said.

every woman descends from a female ancestor who had 12+ kids. having a kid at 35+ is extremely NORMAL and you are not contributing anything anyone doesn't know to this conversation.

[Anonymous]

ChatGPT is great for a lot of things but not really persuasive essays

My advice would be, look up statistics on the things you most worry about, and then you and your husband can evaluate the level of risk and your respective tolerance for risk. Maybe consult with your OB or a genetic counselor. On the one hand, risks are elevated. On the other hand, most people will not experience those outcomes. It's a very personal decision and hopefully both of you will end up on the same page.

[Anonymous]

Anonymous wrote:I have two beautiful children that I had at ages 31 and 33. I am 35 now and my husband and I are arguing over whether to have a third. I desperately want one more, but he leans no (with the door still open enough to give me hope), and one of his reasons is that he's so worried about the risk of a baby with something wrong with it (chromosomal, special needs, birth defect etc). He says it's a prospect he can't even bear, especially because of how unfair that would be to the older two.

I would like to give him data or reassurance, but I can't deny that the fear seeps into me, too, not to mention how guilty I'd feel if something did happen after he was so open about his fear.

Can anyone share resources for this, or know off-hand what the general risks would be? By the time this baby would be born we would be 36 (almost 37) and 37 (DH). We have no family history of health issues. We did genetic testing and are clear. We have two healthy, full term, normal weight babies with healthy noneventful pregnancies.

Thank you!

Just avoid alcohol. Even small amounts can cause issues.

[Anonymous]

Talk to your OB/GYN about genetic risks. Ask questions until you have your questions answered. Do not take DCUM as if it were a set of medical experts.

[Anonymous]

Anonymous wrote:… avoid alcohol. Even small amounts can cause issues.

Avoiding any alcohol is excellent advice for anyone pregnant. Even if DC comes out and seems normal, one will never know how much better the DC might have been if not exposed to fetal alcohol. Fetal alcohol syndrome can cause obvious severe issues or can cause milder non-obvious impairments.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Be concerned and monitor closely don't listen to the people on here they think they can defy science

this isn't defying science - the women of yesteryear who had 12+ children were all having children past 35. you have no idea WHAT you are talking about.

It is important to address the issue of misinformation and emphasize the potential dangers associated with women having children past the age of 35. Here is a strong refutation, supported by statistics, to discourage the spread of misinformation:

It is imperative to stop spreading misinformation and instead rely on scientific evidence and expert advice when discussing matters of reproductive health. Dismissing the risks associated with advanced maternal age is not only irresponsible but also potentially harmful. Allow me to provide you with compelling statistics that highlight the dangers of women having children past the age of 35:

1. Increased risk of chromosomal abnormalities: Scientific research consistently shows that the risk of chromosomal abnormalities, such as Down syndrome, significantly increases with maternal age. According to the American College of Obstetricians and Gynecologists (ACOG), the risk of Down syndrome at age 35 is about 1 in 200, while at age 40, it becomes approximately 1 in 100, and by age 45, it rises to about 1 in 30. These statistics clearly demonstrate the substantial escalation in risk as women age.

2. Higher risk of pregnancy complications: Advanced maternal age is associated with a higher likelihood of experiencing various pregnancy complications. According to a study published in the Journal of Obstetrics and Gynaecology Canada, women aged 35 and older have an increased risk of gestational diabetes, preeclampsia, placenta previa, and premature birth. These complications can pose serious health risks to both the mother and the baby.

3. Decreased fertility and increased miscarriage risk: Women in their late 30s and beyond experience a decline in fertility. The ACOG reports that after the age of 35, a woman's chances of getting pregnant each month decrease significantly. Additionally, the risk of miscarriage also rises with advancing maternal age. According to a study published in the journal Fertility and Sterility, women aged 35-39 have a 20% chance of miscarriage, which increases to 35% for women aged 40-44.

4. Increased likelihood of pregnancy interventions: Advanced maternal age often necessitates additional medical interventions during pregnancy. Women over 35 are more likely to require assisted reproductive technologies, such as in vitro fertilization (IVF), to achieve pregnancy. These interventions can be physically and emotionally taxing, as well as financially burdensome.

By spreading misinformation, you are disregarding the well-established scientific knowledge and putting women and their potential children at risk. It is crucial to prioritize evidence-based information and encourage individuals to consult healthcare professionals who can provide accurate guidance based on each person's unique circumstances.

I implore you to stop spreading dangerous misinformation and instead advocate for responsible and informed discussions that prioritize the health and well-being of women and their children. Science offers us invaluable insights that should guide our decisions and actions for the betterment of society as a whole.

nothing you said contradicts or adds insight to what i said.

every woman descends from a female ancestor who had 12+ kids. having a kid at 35+ is extremely NORMAL and you are not contributing anything anyone doesn't know to this conversation.

A 1 in 200 chance of Down syndrome is a 99.5 percent chance of no down syndrome. Most babies born at 35 will still be perfectly healthy, in line with anecdotes.

[Anonymous]

I would talk with your husband (and yourself via a therapist, confidant, or pastor) about how you feel about termination for medical reasons at both early and later stages. Testing is extremely accurate now such that you would know pretty early about almost all chromosomal issues. That said you kid could be colicky, have adhd, odd, or any other personality issues that will obviously affect your family dynamic and older children. Or they could be the light of everyone and bring everyone closer together. But If your dh is worried and hesitant I would be reluctant to add a third.

I had a surprise pregnancy at 45. My dh was thrilled and did not want me to tfmr but I was prepared to consider that depending on the issue. My kids have become more independent and were always close to eachother and their dad so that has worked out while I am in baby mode and have had to detach from them more. But both parents have to be all in obviously.

[Anonymous]

As someone who has a younger sibling with significant disabilities that were not accurately predicted in womb (my mom was 35), it is devastating for the family. My parents have sacrificed a lot; they never can go anywhere on their own, their life fully revolves around taking care of my sibling, and sibling will live with them lifelong. Once they pass, I know I will have sibling move in with me. If you’re concerned about the risk at all — and the risk does increase the older you are — I would not do it. If you ended up with a child that had significant needs, that will be very hard on your marriage, your life, and your other kids. Of course there are many people who ended up with healthy and happy kids post 35, but the question is not whether it’s possible, it’s whether you’re willing to risk it.

[Anonymous]

Anonymous wrote:

Anonymous wrote:My SIL had BOTH her kids after 35 (38 and 43) and both came out with zero defects or delays. The two people I know whose babies had Downs were under 35 when their kids were born.

While it is commendable that your SIL had healthy children after the age of 35, it is important to note that individual anecdotes cannot be used to make generalizations or dismiss the potential risks associated with advanced maternal age. Here are some statistics and information to refute the statement and highlight the dangers of spreading misinformation:

1. Increased risk of chromosomal abnormalities: Advanced maternal age, typically defined as 35 years and older, is associated with a higher risk of chromosomal abnormalities in babies. For example, the risk of Down syndrome significantly increases with maternal age. According to the Centers for Disease Control and Prevention (CDC), the risk of having a baby with Down syndrome at age 35 is about 1 in 350, while at age 40, it increases to about 1 in 100, and by age 45, it becomes approximately 1 in 30.

2. Risk of other genetic disorders: Advanced maternal age also increases the risk of other genetic disorders, such as trisomy 18 and trisomy 13. These conditions can lead to severe developmental delays, intellectual disabilities, and various physical abnormalities.

3. Health complications for the mother: Pregnancy after the age of 35 carries higher risks for the mother as well. Women of advanced maternal age have an increased likelihood of developing gestational diabetes, high blood pressure, and other pregnancy-related complications. These conditions can have long-term health consequences for both the mother and the baby.

4. Statistical evidence: While anecdotes can be compelling, it is crucial to rely on broader statistical evidence to assess risks accurately. Large-scale studies and data analysis consistently demonstrate an association between advanced maternal age and an increased likelihood of chromosomal abnormalities and other pregnancy complications.

5. Consultation with healthcare professionals: When it comes to matters of pregnancy and reproductive health, it is always advisable to consult with healthcare professionals who can provide evidence-based information tailored to individual circumstances. They can assess personal risk factors, provide appropriate prenatal testing options, and offer guidance based on the most up-to-date medical knowledge.

It is essential to stop spreading dangerous information that downplays the potential risks associated with advanced maternal age. By relying on accurate statistics and seeking reliable medical advice, individuals can make informed decisions about their reproductive health and better understand the potential challenges they may face.

Wow you know OPs chance of having a baby with Down Syndrome is 1 in 400. Also, do you know people with Down Syndrome generally live fairly "normal" lives until they get early on set Alzheimers in their 50s, so perhaps this concern for siblings is over blown. The fear mongering of Down Syndrome and the selfishness of people who will not have supposedly perfect kids is astonishing. You know you all have a 1 in 34 chance of having a child with Autism today - can we screen to kill all of these kids too asap?

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:My SIL had BOTH her kids after 35 (38 and 43) and both came out with zero defects or delays. The two people I know whose babies had Downs were under 35 when their kids were born.

While it is commendable that your SIL had healthy children after the age of 35, it is important to note that individual anecdotes cannot be used to make generalizations or dismiss the potential risks associated with advanced maternal age. Here are some statistics and information to refute the statement and highlight the dangers of spreading misinformation:

1. Increased risk of chromosomal abnormalities: Advanced maternal age, typically defined as 35 years and older, is associated with a higher risk of chromosomal abnormalities in babies. For example, the risk of Down syndrome significantly increases with maternal age. According to the Centers for Disease Control and Prevention (CDC), the risk of having a baby with Down syndrome at age 35 is about 1 in 350, while at age 40, it increases to about 1 in 100, and by age 45, it becomes approximately 1 in 30.

2. Risk of other genetic disorders: Advanced maternal age also increases the risk of other genetic disorders, such as trisomy 18 and trisomy 13. These conditions can lead to severe developmental delays, intellectual disabilities, and various physical abnormalities.

3. Health complications for the mother: Pregnancy after the age of 35 carries higher risks for the mother as well. Women of advanced maternal age have an increased likelihood of developing gestational diabetes, high blood pressure, and other pregnancy-related complications. These conditions can have long-term health consequences for both the mother and the baby.

4. Statistical evidence: While anecdotes can be compelling, it is crucial to rely on broader statistical evidence to assess risks accurately. Large-scale studies and data analysis consistently demonstrate an association between advanced maternal age and an increased likelihood of chromosomal abnormalities and other pregnancy complications.

5. Consultation with healthcare professionals: When it comes to matters of pregnancy and reproductive health, it is always advisable to consult with healthcare professionals who can provide evidence-based information tailored to individual circumstances. They can assess personal risk factors, provide appropriate prenatal testing options, and offer guidance based on the most up-to-date medical knowledge.

It is essential to stop spreading dangerous information that downplays the potential risks associated with advanced maternal age. By relying on accurate statistics and seeking reliable medical advice, individuals can make informed decisions about their reproductive health and better understand the potential challenges they may face.

Wow you know OPs chance of having a baby with Down Syndrome is 1 in 400. Also, do you know people with Down Syndrome generally live fairly "normal" lives until they get early on set Alzheimers in their 50s, so perhaps this concern for siblings is over blown. The fear mongering of Down Syndrome and the selfishness of people who will not have supposedly perfect kids is astonishing. You know you all have a 1 in 34 chance of having a child with Autism today - can we screen to kill all of these kids too asap?

Tell you what - you pay for all the medical interventions and treatments a Downs child I could have will need and then we can talk.

[Anonymous]

I’m not willing to risk it.