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[quote=Anonymous]Hi OP, I've been on tirzepatide for a year now. I had a lot to lose, and I have lost it. I don't know yet whether I'll be on it for life or not, but I might be. I do expect to be titrating it and/or spacing it out during the next year - while I figure out what maintenance will look like for me.

Over the course of this year I have spaced out or titrated my shots several times. Sometimes because I was travelling and couldn't manage the refrigeration aspect. Sometimes because it was the holidays and I wanted less appetite suppression. Occasionally it was accidental because I just forgot that it was "shot day". In the beginning  (the first couple of weeks) I had to make sure I was eating enough and that was a bizarre life adjustment!

It is important to make sure you're taking in enough calories to give you energy, not trick your body into thinking you're starting (you don't want to trigger any metabolic weirdness) and maintain your health.

I think there is zero harm in waiting a day, two, or three before your next shot. If you had side effects from the medication when you started you might not want to wait beyond a few days, just so you don't have to start over w/ adjusting to it.

You are on essentially the starting dose, which for many isn't even effective. You are lucky! You could reduce that dose to 1.5 perhaps and see if that allows back a bit more appetite. While you don't need to do this long term to get where you want to be, you do want to be taking calories in - zero food intake isn't a good idea.

So yes - I'd wait a few days. Try to make sure you're eating (protein for starters. Protein shakes, prosciutto and cheese, a nice steak, etc...) Then see how it goes. You'll figure it out in the long run.[/quote]

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