Reply to is RKFJr's "Tylenol(TM) causes autism" just a shakedown for extortion money from the company?

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Reply to "is RKFJr's "Tylenol(TM) causes autism" just a shakedown for extortion money from the company? "

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I don’t know why all of you are getting worked up over this. You’re free to ingest as much Tylenol as you wish while pregnant. 
It’s still legal.[/quote]

At what point do these recommendations affect what insurance companies will cover or doctors' liability for compliant or non-compliant advice?[/quote]

lol DCUM freaking out that Tylenol won’t be covered by insurance. Chefs kiss. [/quote]

It's not about insurance coverage. It's about misleading information -- deliberately wrong information.

Tylenol is safe in pregnancy. The other options OTC are not, especially past the 30 week time. And untreated fever in pregnancy really IS connected to autism.[/quote]

And what will end up happening after this is women leaving fever untreated or thinking "I heard Tylenol is bad, I will take Ibuprofen instead." 
[/quote]

The risk is premature closure of the PDA [i]in utero[/i], leading to fetal death.

[b]Tylenol is safe in pregnancy.[/b][/quote]

How do you know?[/quote]

Because a giant study of 2.5 million children which controlled for genetic and familial factors found that any correlation with autism disappeared once those confounding factors were controlled for. In other words, the correlation found in some studies is related to confounds - genetics of who is more likely to take tylenol due to other predisposing factors. [/quote]

That’d be a totally satisfactory response if there weren’t studies pointing in the other direction, but there are. Why don’t you credit those?[/quote]

DP. Because they are lower quality research. The way health care studies are compared is using the GRADE tool. Cite your favorite of any of those threads, and we can compare the GRADE score in detail.

[quote][b]Introduction to the GRADE tool for rating certainty in evidence and recommendations[/b]
https://www.sciencedirect.com/science/article/pii/S2213398423002713

The GRADE (Grading of Recommendations Assessment, Development, and Evaluation) tool is a systematic approach used to assess the certainty of evidence and strength of recommendations in healthcare guidelines. It emphasizes the importance of considering the strengths and weaknesses of the evidence, as well as values, preferences, and practical considerations when making healthcare decisions. The GRADE methodology aims to enhance transparency, consistency, and rigor in evaluating evidence and informing clinical decision-making. GRADE uses a structured approach to assign a rating of high, moderate, low, or very low certainty to the evidence. Factors affecting certainty—study design, risk of bias, inconsistency, indirectness, imprecision, and publication bias—are considered in rating the certainty or confidence in evidence. [/quote][/quote]

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