Reply to Telling My Kids About Their IVF Story??

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Op get a life and stop trolling.  Do share the “scientific method” available to assess the IQ of a fetus.  [/quote]
There are companies that run polygenic scores for IQ on embryo DNA data. A few people have already done this and I’m one of these people. This practice is not common yet, but will likely become more common over time. This is a serious question and I’m asking for answers on what age it’s appropriate to tell the kids about it. [/quote]

Oh really? Name them and cite the evidence behind them.  And then go out and find something productive to do with your life other than trolling.[/quote]
NP. This seems to be latest bandwagon for the wealthy:
https://www.nytimes.com/interactive/2025/04/01/opinion/ivf-gene-selection-fertility.html?unlocked_article_code=1.FU8.Pn-E.gU7a6PzjK1_k&smid=url-share[/quote]

Did you actually read the article you posted? No one is claiming to screen embryos for IQ.  One company has said they are looking at genetic factors that could cause intellectual disabilities but that’s not the same thing, and that is just what they’re claiming to do. there’s no evidence in the form of peer reviewed scientific research for any of this.  [/quote]
Where did I say there was? I thought it was obvious that this is bunk.[/quote]

There is a decent amount of research about polygenic scores. They have done studies to validate the selection methods using sibling pairs from biobank data. For sibling pairs where one has a disease and another does not, they can identify which sibling is affected by the disease more often than random chance. The odd of correctly identifying the sibling (out of a pair) for polygenic diseases using only genetic data ranges from 1.5/1  to 2/1 for most of these diseases. So it is a weighted coin flip, that is not guaranteed to work (at the individual) but it is better than picking randomly.  The gains from selection increase with the number of embryos.

https://www.nature.com/articles/s41598-020-69927-7/tables/1
Dl o
https://pubmed.ncbi.nlm.nih.gov/34635206/
https://www.nature.com/articles/s41598-020-69927-7

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