Reply to GLP1 Celebrity anorexia - are we going to see deaths?

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]There are a number of people in my neighborhood and my office who started ozempic/mounjaro/etc. within the last few years. Here’s what I’ve observed:

The ones who were very overweight and older (50+) are now skeletal and saggy. It’s jarring to see someone lose 100+ pounds. I’ve observed others asking “what’s wrong” or if they have cancer, etc.

The ones who were not very overweight and were just a bit pudgy/flabby got skinny and tighter. They look healthy and just don’t eat much anymore.

I’ve observed most obsessing about their weight and complaining how they just can’t eat much anymore. They seem to struggle to eat half a sandwich.

Every time I go to the GYN the practice asks if I want a consult for a GLP1. I’m 5’9” and hover between 175-180. I’m a size 12/14. I gained 30 pounds when perimenopause started. While I’m tempted to take the magic shot, [b]I can’t get past the feeling that it’s damaging to one’s health. [/b][/quote]

There's been research, study and testing on these drugs going back as far as the '80's. Trials mandated by the FDA to assess cardiovascular risk showed that the drugs actually have a protective effect against cardiovascular disease.

I'm not saying you should consider using a GLP 1 or not, but through science we already know that a healthy BMI reduces disease risk factors and that these drugs have a positive effect on cardiovascular health. Things like muscle loss can be counteracted with weight lifting, which is recommended for women as part of a healthy lifestyle anyway.[/quote]

These studies haven’t been done in people without diabetes. What I think we will see is a good deal of osteoporosis, malnutrition and possibly some unexpected outcome regarding pancreatic function in those populations. I don’t have faith in a lot of people to have the discipline necessary to eat that much less and make sure their nutritional needs are being properly met. I hope I’m wrong but I’ve lived long enough and seen enough “miracles” be adopted quickly only to see lots of poor, unexpected and often deadly outcomes. 
[/quote]

Are people with diabetes not susceptible to osteoporosis and malnutrition (which seems like an absurd claim)?[/quote]

No one "claimed" that.

And the dosing is different -- any first year med or pharmacy student can tell you that the only difference between medicine and poison is dose. [/quote]

The PP claimed exactly that - “  What I think we will see is a good deal of osteoporosis, malnutrition…”

As far as the dose - nice quip, but do you have any evidence that short term higher doses of these medications are poison? Or just vibes?[/quote]

I wrote that post and I didn’t claim anything. I presented suppositions. If you don’t know the difference between a claim and a supposition that’s on you. Why is any  comment other than “This is the best drug ever!” received by you as a personal attack? [/quote]

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