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Reply to "is RKFJr's "Tylenol(TM) causes autism" just a shakedown for extortion money from the company? "
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[quote=Anonymous]Trump said "run from Tylenol, fight it, don't let them give it to you," presumably to pregnant women. Maybe everyone. You know what my OB-Gyn colleagues are talking about? Pregnant women have pain. Sometimes, a lot of pain. There's no reason not to take Tylenol, but some of them are going to remember this erroneous "Tylenol causes autism" thing and reach for an NSAID like aspirin or ibuprofen, which really IS dangerous in pregnancy. There's a decent risk of ductal closure in the fetus when NSAIDs are taken after 30 weeks gestation. That will cause [i]in utero[/i] death in a matter of hours. By the time they notice no fetal movement and someone figures it out, it's too late. That's not going to happen every time, but ibuprofen is one medication neonatologists can give newborns when they need to close a persistent PDA (patent ductus arteriosus). So. That will be great. [quote][b]Ibuprofen lysine (NeoProfen) for the treatment of patent ductus arteriosus[/b] https://pmc.ncbi.nlm.nih.gov/articles/PMC1769541/ For years, indomethacin has been the drug of choice for the treatment of PDA in the USA. Undesirable adverse effects prompted researchers to seek alternative agents. In April 2006, the US Food and Drug Administration approved the use of ibuprofen lysine (NeoProfen) for closure of clinically significant PDA in premature neonates. Ibuprofen's mechanism of action for closure of PDA is believed to be through the inhibition of prostaglandins. Clinical studies have shown ibuprofen to be as effective as indomethacin with fewer adverse effects.[/quote][/quote]
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