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Infertility Support and Discussion
Reply to "Would you do a FET with only fair embryos?"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]The trouble is that you might end up having a child with one of those fair to poor embryos. And that child might have significant mental/physical/emotional challenges. If your desire to have a child is greater than your fear of raising a severely disabled one, then go ahead. Because it's not just the idea that it won't take that you have to consider, it's the fact that perhaps the reason they are poor embryos is because they won't make very great persons. The clinic won't tell you this because obviously any baby is a good baby for them - but for you, it's potentially the next sixty years of your life caring for someone who doesn't function well. [/quote] No. There is no correlation between embryo quality and whether or not that embryo is genetically normal. Of my 7 "excellent" day 5 blasts, only 3 of them were PGS normal. Likewise, I know quite a few people with lower quality embryos that resulted in successful pregnancies.[/quote] There is absolutely correlation between embryo grades and PGS normal embryos. Here is a nice table from Fertility and Sterility. https://www.fertstert.org/article/S0015-0282(15)01380-1/pdf Of course, individual lower graded embryos can be PGS normal and perfect AA embryo can be abnormal. But broadly, higher graded embryos are more likely to be PGS normal. [/quote] this is not the relevant question. Of course there is a correlation between the grade and normality - that’s why hey do the grading. However the question is if poor looking and great looking embryos made it to a live baby is a poor grades one more likely to have a genetic defect. The answer to that is no.[/quote]
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