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[quote=Anonymous][quote=Anonymous]She currently takes abilify, Zoloft, guanfacine, and trazadone. [/quote]

OP I'm so sorry to hear this, what you're going through is incredibly difficult and there's no easy fix. Have been there to some extent with our daughter. 
You may have already done this and her doctor may have accounted for, but if not recommend checking for drug-drug interactions.
Webmd has a tool you can use:
https://www.webmd.com/interaction-checker/default.htm

Drugs: Aripiprazole/Abilify, Sertraline/Zoloft, Guanfacine, Trazodone
9 Interactions Found

SERIOUS
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed.

[b]Sertraline + Trazodone[/b]
Sertraline and Trazodone both increase causing a dangerous abnormal heart rhythm.
Sertraline and Trazodone both increase affecting serotonin levels in the blood. Too much serotonin is a potentially life-threatening situation. Severe signs and symptoms include high blood pressure and increased heart rate that lead to shock.

[b]Trazodone + Guanfacine[/b]
Trazodone decreases effects of Guanfacine by Other mechanism.

[b]Aripiprazole + Trazodone[/b]
Aripiprazole and Trazodone both increase causing a dangerous abnormal heart rhythm.

MONITOR CLOSELY
Significant interaction possible (monitoring by your doctor required).

Guanfacine + Aripiprazole
Guanfacine , Aripiprazole Mechanism: additive drug effects.
Additional Information: Caution, blood pressure may drop and chances of delerium may increase.

Sertraline + Aripiprazole
Sertraline will increase the level or effect of Aripiprazole by altering drug metabolism.
Sertraline and Aripiprazole both increase causing a dangerous abnormal heart rhythm.

Sertraline + Guanfacine
Sertraline will increase the level or effect of Guanfacine by altering drug metabolism.
Additional Information: Blood levels of guanfacine may increase. The dose of extended release guanfacine should be reduced by half.

Aripiprazole + Trazodone
Aripiprazole and Trazodone both increase sedation and drowsiness.

DISCLAIMER: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider.

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