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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Hemophilia, in one famous case.[/quote] Umm, no. You only need 1 copy of the bad gene to have the problem if you are male. In inbreeding, a single mutation is then passed to one chromosome of multiple relatives and eventually some of their descendents end up with two copies of the same recessive gene which causes the problem. Hemophilia came from Queen Victoria and the big problem was that she had 12 children and they married royalty throughout Europe, spreading this gene. [/quote] And who kept marrying each other, thereby increasing the occurrences.[/quote] Actually, no. The PP is right. The problem was that she had 12 children and they married royalty throughout Europe, spreading this gene. This is not a cousin-marriage issue. https://en.wikipedia.org/wiki/Haemophilia_in_European_royalty[/quote]
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