Anonymous
Post 04/15/2016 07:36     Subject: If 1st cousins keep mating generation after generation ...

Anonymous wrote:
Anonymous wrote:
Anonymous wrote:Hemophilia, in one famous case.


Umm, no. You only need 1 copy of the bad gene to have the problem if you are male. In inbreeding, a single mutation is then passed to one chromosome of multiple relatives and eventually some of their descendents end up with two copies of the same recessive gene which causes the problem.

Hemophilia came from Queen Victoria and the big problem was that she had 12 children and they married royalty throughout Europe, spreading this gene.


And who kept marrying each other, thereby increasing the occurrences.


Actually, no. The PP is right. The problem was that she had 12 children and they married royalty throughout Europe, spreading this gene. This is not a cousin-marriage issue.

https://en.wikipedia.org/wiki/Haemophilia_in_European_royalty
Anonymous
Post 04/15/2016 07:33     Subject: If 1st cousins keep mating generation after generation ...

Anonymous wrote:
Anonymous wrote:Hemophilia, in one famous case.


Umm, no. You only need 1 copy of the bad gene to have the problem if you are male. In inbreeding, a single mutation is then passed to one chromosome of multiple relatives and eventually some of their descendents end up with two copies of the same recessive gene which causes the problem.

Hemophilia came from Queen Victoria and the big problem was that she had 12 children and they married royalty throughout Europe, spreading this gene.



And who kept marrying each other, thereby increasing the occurrences.
Anonymous
Post 04/15/2016 07:30     Subject: If 1st cousins keep mating generation after generation ...

Look up the pharaohs of Egypt. Lots of inbreeding there.
Anonymous
Post 04/15/2016 07:26     Subject: If 1st cousins keep mating generation after generation ...

Anonymous wrote:
Anonymous wrote:Any recessive genetic disorders in that family start cropping up.


This.

Which is why marrying a first cousin is illegal in many countries.



It is illegal in some countries. Whereas in other countries, it's a common custom.
Anonymous
Post 04/14/2016 23:06     Subject: If 1st cousins keep mating generation after generation ...

Not OP- This happened twice in a great uncle's line of the family. Those descendants are all very nice but are definitely "slow"
Anonymous
Post 04/14/2016 23:00     Subject: If 1st cousins keep mating generation after generation ...

Anonymous
Post 04/14/2016 22:57     Subject: If 1st cousins keep mating generation after generation ...

Their skin can turn blue.
Anonymous
Post 04/14/2016 22:52     Subject: If 1st cousins keep mating generation after generation ...

Anonymous wrote:Any recessive genetic disorders in that family start cropping up.


This.

Which is why marrying a first cousin is illegal in many countries.

Anonymous
Post 04/14/2016 22:50     Subject: If 1st cousins keep mating generation after generation ...

Anonymous wrote:Hemophilia, in one famous case.


Umm, no. You only need 1 copy of the bad gene to have the problem if you are male. In inbreeding, a single mutation is then passed to one chromosome of multiple relatives and eventually some of their descendents end up with two copies of the same recessive gene which causes the problem.

Hemophilia came from Queen Victoria and the big problem was that she had 12 children and they married royalty throughout Europe, spreading this gene.
Anonymous
Post 04/14/2016 22:43     Subject: If 1st cousins keep mating generation after generation ...

Hemophilia, in one famous case.
Anonymous
Post 04/14/2016 22:42     Subject: If 1st cousins keep mating generation after generation ...

Habsburg jaw. Ugh.
Anonymous
Post 04/14/2016 22:38     Subject: If 1st cousins keep mating generation after generation ...

I'm a bit afraid to ask, but why do you want to know?
Anonymous
Post 04/14/2016 22:23     Subject: If 1st cousins keep mating generation after generation ...

Any recessive genetic disorders in that family start cropping up.
Anonymous
Post 04/14/2016 22:23     Subject: If 1st cousins keep mating generation after generation ...

Oh my.
Anonymous
Post 04/14/2016 22:22     Subject: If 1st cousins keep mating generation after generation ...

Any medical professionals out there? What is the effect on offspring, if first cousins keep producing children, generation after generation. Does this do something to their brain?