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Expectant and Postpartum Moms
Reply to "Maternit21"
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[quote=afield]Here's some more info based on my own experience, as partner to an expectant mom. Our MFM did the screening with blood and NT and the weighted T21 probability was like 1:2400. And we have twins aboard, so its really significantly lower than that, even. Analysts continue to simply "double" risk when twins are present, but it is more complicated than that. Its more like only 18% higher when properly weighted (Cuckle, J Med Screen 1998;5:3–4). I asked about Maternit21, and was told that such cell-free DNA tests are good, and work even with twins, but have a higher rate of false positive than the 1:2400 we are dealing with now. So it is more likely that the test itself would yield a false positive than either child actually have the situation which is being screened for. I was told they don't recommend it, and it would be a waste of money (by my insurance complany) but would be covered. But the statistical argument had me sold already on avoiding it. [/quote]
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