Reply to Donor Cycle Failure - doctor recommends moving on to surrogate but that seems premature?

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[quote=Anonymous][quote=Anonymous]Why won’t they do a DNA fragmentation test? My doctor at SG ordered one after 2 failed FETs.[/quote]

OP here - glad to hear other doctors recommend the test.  Both my SGF doctor and the urologist my husband went to said the test wasn’t useful because the studies didn’t show it to be a good predictor - i.e., there’s no proof that sperm with high fragmentation affects the embryo quality.  I have read recent studies (in 2020-2021) that disagree with that though. Before moving on to donor eggs I was a CCRM and my doctor there had suggested doing another OE cycle using 50% donor sperm to see if sperm could be the issue.  I ended up deciding to move on to donor egg so we didn’t try that and moved back to SGF so that we could do the shared risk.  We asked my SGF doctor if it would be worthwhile to try donor embryo and his opinion was that it would not be because it’s a uterus issue (although there’s no physical indication of any uterus or lining issues).[/quote]

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