Reply to Would you do a CVS with a PGS-tested embryo?

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[quote=Anonymous][quote=Anonymous][quote=Anonymous]All diagnostic test have a risk of MC. Are you willing to take that risk?

I know someone in a group I'm in that had a PGS tested embryo so forgo any blood tests (only the nuchal screening) and it turned out to have one of the Trisonomies. Terminated (or it died in utero, I can't remember) in the early 20's weeks. [/quote]

So how did she end up with a Trisomy? Was PGS wrong?[/quote]

I'm not the PP, but PGS doesn't catch everything.  I had a triploid, which is a third copy of every chromosome, so 69XX.  I was told that PGS would not have picked this up because it looks for balance.  When you have a trisomy on an individual chromosome, there is an imbalance that can be detected, but when every chromosome has an extra, it is not out of balance as a whole.  That pregnancy went to 11 weeks, and that mutation can go into the second trimester, as well.

What is the current miscarriage risk for CVS?  When exactly is it done?  Is it more or less risk than amnio?[/quote]

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